Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9045401

    Methods for treating or ameliorating a melanoma and killing melanoma cells

    The Regents of the University of California · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9044398

    Abuse-deterrent pharmaceutical compositions of opiods and other drugs

    Collegium Pharmaceutical, Inc. · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9045416

    WNT protein signalling inhibitors

    The Board of Regents of the University of Texas System · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9044514

    Lipid-peptide-polymer conjugates and nanoparticles thereof

    The Regents of the University of California · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9044509

    Inhibition of HIV infection through chemoprophylaxis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9044498

    Lyophilized viral formulations

    ONCOLYTICS BIOTECH INC. · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9044483

    Cell death inhibition by macrophage migration inhibitory factor and a binding substance thereto

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9044482

    Use of aminoindane compounds in treating overactive bladder and interstitial cystitis

    Asana BioSciences, LLC · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9044470

    Iminosugars and methods of treating viral diseases

    United Therapeutics Corporation · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9044451

    Use of delta tocopherol for the treatment of lysosomal storage disorders

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9044444

    Method for improving skin appearance and reducing hair loss

    China Medical University · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9044423

    Alcoholic compositions having a lowered risk of acetaldehydemia

    Deuteria Beverages, LLC · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9044420

    Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses

    IMMUNE DESIGN CORP. · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9044419

    Vaccine compositions compromising βs-crystallin for inducing immune responses against components of drusen

    Northwestern University · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9044392

    Nylon-3 co-polymers and synthetic lung surfactant compositions containing same

    Northwestern University · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9044381

    Method for delivering drugs to the brain

    Board of Regents of the University of Nebraska by and behalf of the University of Nebraska Medical Center · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9044473

    Delivery of therapeutic compounds to the brain and other tissues

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9045476

    Inhibition of quorum sensing-mediated processes in bacteria

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9045496

    N-substituted oxazinopteridines and oxazinopteridinones

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9044391

    Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery

    The Board of Regents of the University of Texas System · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9044442

    Peptidomimetic compounds as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9044454

    Regulation of microvasculature occlusion

    Northwestern University · Granted Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9050263

    Pharmaceutical compositions for the treatment of Helicobacter pylori

    RedHill Biopharma Ltd. · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9051271

    Substituted pyridine derivatives useful in the treatment of cancer

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9051379

    Sp1 polypeptides, modified Sp1 polypeptides and uses thereof

    Fulcrum SP Ltd. · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9050298

    Method of treating ischemia/reperfusion injuries to a heart with netrin-1

    The Regents of the University of California · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9051270

    Pyridone amides as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9050302

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9051567

    Methods for increasing efficacy of lipid formulated siRNA

    Tekmira Pharmaceuticals Corporation · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9051570

    UNA oligomers for therapeutics

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9051550

    Cellular seeding and co-culture of a three dimensional fibroblast construct

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9051319

    Inhibitors of influenza viruses replication

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9051342

    Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation related diseases

    PTC THERAPEUTICS, INC. · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9051324

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9051312

    Methods of treating dyskinesia and related disorders

    Melior Discovery, Inc. · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9051303

    Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-YL)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan-2-YL)-1H-indol-5-YL)-cyclopropanecarboxamide

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9050376

    Conjugates of synthetic TLR agonists and uses therefor

    The Regents of the University of California · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9050378

    N2S2 chelate-targeting ligand conjugates

    The Board of Regents of the University of Texas System · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9051249

    Benzylamine derivatives as inhibitors of plasma kallikrein

    KalVista Pharmaceuticals Limited · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9050372

    High molecular weight derivatives of vitamin K-dependent polypeptides

    Regents of the University of Minnesota · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9050343

    Combination of pimavanserin and risperidone for the treatment of psychosis

    ACADIA Pharmaceuticals Inc. · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9050299

    Administration of growth factors for the treatment of CNS disorders

    The Regents of the University of California · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9050285

    Recombinant bacterium capable of eliciting an immune response against Streptococcus pneumoniae

    The United States of America National Institutes of Health (NH), U.S. Dept. of Health and Human Services (DHHS) · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9050300

    Surgical applications for BMP binding protein

    THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9050311

    Compounds and methods for delivery of prostacyclin analogs

    United Therapeutics Corporation · Granted Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 04 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 2015158906

    Method of Purifying Therapeutic Proteins

    CSL LTD [AU] · Granted Thu Jun 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 06 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9057069

    Compositions and methods for inhibiting expression of Eg5 gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jun 16 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 11 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9057104

    Antipsychotic treatment based on DRD2 or ANKK1 SNP genotype

    VANDA PHARMACEUTICALS INC. · Granted Tue Jun 16 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 11 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.