Wednesday, July 8, 2026

Drug profile · INN

theophylline

theophylline (NUELIN) is a phosphodiesterase 4 inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 2
Pipeline programs 4
News articles 0
Drug details — theophylline
US status
approved
Class
Route
INJECTION
Patents
2
Programs
4
Data quality
0.89

Quick answer

theophylline (NUELIN) is a phosphodiesterase 4 inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN theophylline
Brand NUELIN
Mechanism Phosphodiesterase 4 inhibitor
Target Adenosine receptor
Route INJECTION
Formulation TABLET, EXTENDED RELEASE

Mechanism of action

Phosphodiesterase 4 inhibitor

Primary target: Adenosine receptor

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. CRT with triple site ventricular stimulation Phase 3 · Rhythm Pharmaceuticals Netherlands · Heart Failure
  2. CRT Approved · Rhythm Pharmaceuticals Netherlands · Heart Failure
  3. CRT + AOP Approved · Rhythm Pharmaceuticals Netherlands · Heart Failure
  4. theophylline Approved · Takeda · Healthy

Related & competitor drugs

  1. adenosine Adenosine receptor agonist
  2. aminophylline Adenosine receptor antagonist
  3. caffeine citrate Nervous system (N06)
  4. caffeine Nervous system (N06)
  5. istradefylline Nervous system (N04)
  6. oxtriphylline Phosphodiesterase 3 inhibitor
  1. US 9107912

    Methods for concomitant treatment of theophylline and febuxostat

    Expires Mon Aug 13 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8372872

    Methods for concomitant treatment of theophylline and febuxostat

    Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is theophylline?

theophylline (NUELIN) is a phosphodiesterase 4 inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for theophylline?

NUELIN is a marketed brand name for theophylline. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of theophylline?

theophylline has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.