Wednesday, July 8, 2026

Drug profile · INN

caffeine

caffeine (PEYONA (PREVIOUSLY NYMUSA)) is a adenosine receptor antagonist. Route of administration: rectal. Current US regulatory status: approved.

FDA: approved EMA: approved Nervous system (N06) N06BC01
US status approved
Patents linked 0
Pipeline programs 11
News articles 0
Drug details — caffeine
US status
approved
Class
Nervous system (N06)
Route
RECTAL
Patents
0
Programs
11
Data quality
0.84

Quick answer

caffeine (PEYONA (PREVIOUSLY NYMUSA)) is a adenosine receptor antagonist. Route of administration: rectal. Current US regulatory status: approved.

Key facts

INN caffeine
Brand PEYONA (PREVIOUSLY NYMUSA)
Mechanism Adenosine receptor antagonist
Target Adenosine receptor
Therapeutic class Nervous system (N06)
Route RECTAL
Formulation SUPPOSITORY
ATC code N06BC01

Mechanism of action

Adenosine receptor antagonist

Primary target: Adenosine receptor

Approval history

Authority Status Date
FDA approved
EMA approved

Pipeline programs

  1. Caffeine 150 MG Phase 2 · BRIGHT MINDS BIOSCIENCES · Cocaine Dependence
  2. Caffeine citrate Phase 2 · BRIGHT MINDS BIOSCIENCES · Retinopathy of Prematurity
  3. 0352-2190 Phase 1 · Boehringer Ingelheim · 1. Patients with compensated liver cirrhosis due to any unde
  4. 1404-0008 Phase 1 · Boehringer Ingelheim · Overweight, Obesity
  5. Alcohol + Caffeine Beverage Phase 1 · BRIGHT MINDS BIOSCIENCES · Alcohol or Other Drugs Effects
  6. Evaluation of bioequivalence of two products... Phase 1 · Anaxis Pharma · No therapeutic indication in the current trial with healthy
  7. Individualized caffeine cessation instructions Phase 1 · BRIGHT MINDS BIOSCIENCES · Self-identified Problematic Caffeine Use
  8. LE 5101 Phase 1 · Pharming Technologies · Activated Phosphoinositide 3-Kinase Delta Syndrome

Related & competitor drugs

  1. adenosine Adenosine receptor agonist
  2. aminophylline Adenosine receptor antagonist
  3. aripiprazole Nervous system (N05)
  4. brexpiprazole Nervous system (N05)
  5. brivaracetam Nervous system (N03)
  6. bupivacaine Nervous system (N01)

Frequently asked questions

What is caffeine?

caffeine (PEYONA (PREVIOUSLY NYMUSA)) is a adenosine receptor antagonist. Route of administration: rectal. Current US regulatory status: approved.

What is the brand name for caffeine?

PEYONA (PREVIOUSLY NYMUSA) is a marketed brand name for caffeine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of caffeine?

caffeine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.