Wednesday, July 8, 2026

Drug profile · INN

istradefylline

istradefylline (NOURYANT) is a adenosine a2a receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: refused PMDA: approved Nervous system (N04) N04
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — istradefylline
US status
approved
Class
Nervous system (N04)
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

istradefylline (NOURYANT) is a adenosine a2a receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN istradefylline
Brand NOURYANT
Mechanism Adenosine A2a receptor antagonist
Target Adenosine receptor A2a
Therapeutic class Nervous system (N04)
Route ORAL
Formulation TABLET
ATC code N04

Mechanism of action

Adenosine A2a receptor antagonist

Primary target: Adenosine receptor A2a

Approval history

Authority Status Date
FDA approved
EMA refused
PMDA approved

Related & competitor drugs

  1. aripiprazole Nervous system (N05)
  2. brexpiprazole Nervous system (N05)
  3. brivaracetam Nervous system (N03)
  4. bupivacaine Nervous system (N01)
  5. buprenorphine Nervous system (N07)
  6. caffeine citrate Nervous system (N06)

Frequently asked questions

What is istradefylline?

istradefylline (NOURYANT) is a adenosine a2a receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for istradefylline?

NOURYANT is a marketed brand name for istradefylline. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of istradefylline?

istradefylline has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.