Wednesday, July 8, 2026

Drug profile · INN

isosorbide mononitrate

isosorbide mononitrate (APO-ISOSORBIDE MONONITRATE) is a soluble guanylate cyclase activator. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 2
Pipeline programs 1
News articles 0
Drug details — isosorbide mononitrate
US status
approved
Class
Route
ORAL
Patents
2
Programs
1
Data quality
0.89

Quick answer

isosorbide mononitrate (APO-ISOSORBIDE MONONITRATE) is a soluble guanylate cyclase activator. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN isosorbide mononitrate
Brand APO-ISOSORBIDE MONONITRATE
Mechanism Soluble guanylate cyclase activator
Target Soluble guanylate cyclase
Route ORAL
Formulation TABLET

Mechanism of action

Soluble guanylate cyclase activator

Primary target: Soluble guanylate cyclase

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. Isosorbide Mononitrate Phase 2 · United Therapeutics Europe · Kidney Injury

Related & competitor drugs

  1. isosorbide dinitrate Soluble guanylate cyclase activator
  2. nitroglycerin Soluble guanylate cyclase activator
  3. riociguat Cardiovascular system (C02)
  4. sodium nitroprusside Soluble guanylate cyclase activator
  5. nitric oxide Respiratory system (R07)
  6. vericiguat Cardiovascular system (C01)
  1. AR 131518

    COMPUESTO DE 4-AMINOPIPERIDINA, NANOPARTÍCULAS LIPÍDICAS DEL MISMO Y COMPOSICIÓN FARMACÉUTICA QUE CONTIENE EL MISMO

    Expires Tue Mar 21 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. BR PI0614453

    método de redução de cululite indesejada em áreas seletivas de um organismo e mistura fotossensibilizante

    Expires Mon Dec 06 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is isosorbide mononitrate?

isosorbide mononitrate (APO-ISOSORBIDE MONONITRATE) is a soluble guanylate cyclase activator. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for isosorbide mononitrate?

APO-ISOSORBIDE MONONITRATE is a marketed brand name for isosorbide mononitrate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of isosorbide mononitrate?

isosorbide mononitrate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.