Wednesday, July 8, 2026

Drug profile · INN

vericiguat

vericiguat (VERQUVO) is a soluble guanylate cyclase activator. Associated with Bayer Australia Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved NMPA: clinical trials Cardiovascular system (C01) C01
US status approved
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — vericiguat
US status
approved
Class
Cardiovascular system (C01)
Route
ORAL
Patents
0
Programs
3
Data quality
0.84

Quick answer

vericiguat (VERQUVO) is a soluble guanylate cyclase activator. Associated with Bayer Australia Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN vericiguat
Brand VERQUVO
Mechanism Soluble guanylate cyclase activator
Target Soluble guanylate cyclase
Therapeutic class Cardiovascular system (C01)
Route ORAL
Formulation TABLET
ATC code C01

Mechanism of action

Soluble guanylate cyclase activator

Primary target: Soluble guanylate cyclase

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved
NMPA clinical trials

Pipeline programs

  1. MK-1242-043 Phase 3 · MSD Merck Sharp · Heart Failure due to Systemic Left Ventricular Systolic Dysf
  2. Vericiguat Phase 3 · Merck KGaA, Darmstadt · Chronic Heart Failure With Reduced Ejection Fraction
  3. 22342 Phase 1 · Bayer · Heart failure in children

Related & competitor drugs

  1. alirocumab Cardiovascular system (C10)
  2. aliskiren Cardiovascular system (C09)
  3. azilsartan medoxomil Cardiovascular system (C09)
  4. bempedoic acid Cardiovascular system (C10)
  5. bosentan Cardiovascular system (C02)
  6. dofetilide Cardiovascular system (C01)

Frequently asked questions

What is vericiguat?

vericiguat (VERQUVO) is a soluble guanylate cyclase activator. Associated with Bayer Australia Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for vericiguat?

VERQUVO is a marketed brand name for vericiguat. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of vericiguat?

vericiguat has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.