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Intelligence · Clinical pipeline

Phase III Pipeline Programs

Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Programs 5,427
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 5,427 phase iii pharmaceutical pipeline programs from ClinicalTrials.gov. Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Top sponsors

Pipeline programs

Page 59 of 114

  1. Lixivaptan

    Centessa Pharmaceuticals plc

    Polycystic Kidney Disease, Adult

    phase 3 small molecule terminated

    2 trials

  2. Lixivaptan

    Centessa Pharmaceuticals plc

    Autosomal Dominant Polycystic Kidney

    phase 3 small molecule terminated

    1 trial

  3. Loargys 5 mg/ml solution for injection/infusion

    Immedica Pharma AB

    Arginase 1 deficiency (ARG1-D)

    phase 3 small molecule active

    1 trial

  4. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 3 small molecule completed

    3 trials

  5. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Withdrawal

    phase 3 small molecule completed

    1 trial

  6. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Opiate Addiction

    phase 3 small molecule completed

    1 trial

  7. Lofexidine HCl

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Dependence

    phase 3 small molecule completed

    1 trial

  8. Loncastuximab Tesirine

    ADC Therapeutics SA

    Relapsed Diffuse Large B-Cell Lymphoma

    phase 3 small molecule active

    1 trial

  9. Loperamide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Diarrhea-predominant Irritable Bowel Syndrome

    phase 3 small molecule completed

    1 trial

  10. Loperamide

    Chengdu University of Traditional Chinese Medicine

    Diarrhea-predominant Irritable Bowel Syndrome

    phase 3 small molecule completed

    1 trial

  11. Losartan

    BRIGHT MINDS BIOSCIENCES INC.

    Glomerulonephritis, IGA

    phase 3 small molecule completed

    1 trial

  12. Losmapimod

    Fulcrum Therapeutics

    Facioscapulohumeral Muscular Dystrophy (FSHD)

    phase 3 small molecule terminated

    2 trials

  13. Losmapimod oral tablet

    Fulcrum Therapeutics

    COVID-19

    phase 3 small molecule terminated

    1 trial

  14. Low-dose complex B-vitamins

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hyperhomocysteinemia

    phase 3 other completed

    1 trial

  15. Low-dose rtPA

    Takeda

    Ischemic Stroke

    phase 3 small molecule completed

    1 trial

  16. Lu AA21004

    Takeda

    Major Depressive Disorder

    phase 3 small molecule completed

    1 trial

  17. Lu AF35700

    H. Lundbeck A/S

    Treatment-resistant Schizophrenia

    phase 3 small molecule terminated

    1 trial

  18. Lubiprostone

    Takeda

    Constipation - Functional

    phase 3 small molecule completed

    1 trial

  19. Lubiprostone

    Takeda

    Irritable Bowel Syndrome With Constipation

    phase 3 small molecule completed

    1 trial

  20. Lucerastat

    Lacuna Pharma Pty Ltd

    Fabry disease

    phase 3 small molecule active

    1 trial

  21. Lucinactant

    WINDTREE THERAPEUTICS INC /DE/

    Meconium Aspiration

    phase 3 small molecule terminated

    1 trial

  22. Lumacaftor

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 3 small molecule completed

    6 trials

  23. Lumacaftor Plus Ivacaftor Combination

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

    phase 3 small molecule completed

    1 trial

  24. Lumacaftor Plus Ivacaftor Combination

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis, Homozygous or Heterozygous for the F508del-CFTR Mutation

    phase 3 small molecule completed

    1 trial

  25. Lumasiran

    Alnylam Netherlands B.V.

    Primary Hyperoxaluria Type 1

    phase 3 small molecule completed

    1 trial

  26. Lumasiran

    Alnylam Netherlands B.V.

    Primary Hyperoxaluria

    phase 3 small molecule completed

    1 trial

  27. Lurasidone

    Sumitomo Pharma (Suzhou) Co.,

    Bipolar I Depression

    phase 3 small molecule completed

    1 trial

  28. Lutikizumab

    AbbVie

    Hidradenitis Suppurativa

    phase 3 small molecule active

    1 trial

  29. Lutikizumab, Placebo of Lutikizumab

    AbbVie Deutschland GmbH & Co. KG

    Hidradenitis Suppurativa

    phase 3 small molecule active

    1 trial

  30. Luveltamab tazevibulin

    SUTRO BIOPHARMA, INC.

    Ovarian Cancer

    phase 3 small molecule terminated

    1 trial

  31. Lynparza film-coated tablets for Recurrent ovarian cancer

    Fondazione Telethon ETS

    Recurrent ovarian cancer

    phase 3 small molecule active

    1 trial

  32. M-14867-33

    Almirall, S.A.

    Actinic Keratosis on the Face or Scalp

    phase 3 small molecule active

    1 trial

  33. M-17923-34

    Almirall, S.A.

    Atopic Dermatitis

    phase 3 small molecule active

    1 trial

  34. M-27501-30

    Almirall, S.A.

    Nummular Dermatitis

    phase 3 small molecule active

    1 trial

  35. M10-870

    AbbVie Deutschland GmbH & Co. KG

    Ulcerative Colitis

    phase 3 small molecule active

    1 trial

  36. M1095-HS-301

    MoonLake Immunotherapeutics

    hidradenitis suppurativa (HS)

    phase 3 small molecule active

    1 trial

  37. M1095-HS-302

    MoonLake Immunotherapeutics

    hidradenitis suppurativa (HS)

    phase 3 small molecule active

    1 trial

  38. M1095-PSA-301

    MoonLake Immunotherapeutics

    Psoriatic arthritis

    phase 3 small molecule active

    1 trial

  39. M1095-PSA-302

    MoonLake Immunotherapeutics

    psoriatic arthritis

    phase 3 small molecule active

    1 trial

  40. M13-494

    AbbVie Deutschland GmbH & Co. KG

    R/R Multiple Myeloma

    phase 3 small molecule active

    1 trial

  41. M14-533

    AbbVie Deutschland GmbH & Co. KG

    Ulcerative Colitis

    phase 3 small molecule active

    1 trial

  42. M14-671

    AbbVie Deutschland GmbH & Co. KG

    Crohn's Disease (CD)

    phase 3 small molecule active

    1 trial

  43. M14-682

    AbbVie Deutschland GmbH & Co. KG

    juvenile idiopathic arthritis

    phase 3 small molecule active

    1 trial

  44. M15-656

    AbbVie Deutschland GmbH & Co. KG

    Acute Myeloid Leukemia

    phase 3 small molecule active

    1 trial

  45. M15-954

    AbbVie Deutschland GmbH & Co. KG

    Higher-Risk Myelodysplastic Syndrome

    phase 3 small molecule active

    1 trial

  46. M15-998

    AbbVie Deutschland GmbH & Co. KG

    Psoriatic Arthritis

    phase 3 small molecule active

    1 trial

  47. M16-000

    AbbVie Deutschland GmbH & Co. KG

    Crohn's Disease

    phase 3 small molecule active

    1 trial

  48. M16-011

    AbbVie Deutschland GmbH & Co. KG

    Psoriatic Arthritis

    phase 3 small molecule active

    1 trial

Frequently asked questions

How many Phase III pipeline programs are in the directory?

5,427 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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