Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase III Pipeline Programs

Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Programs 5,427
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 5,427 phase iii pharmaceutical pipeline programs from ClinicalTrials.gov. Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Top sponsors

Pipeline programs

Page 12 of 114

  1. ARGX-117-2402

    argenx

    Chronic inflammatory demyelinating polyneuropathy (CIDP)

    phase 3 small molecule active

    1 trial

  2. ARN-509-003

    Lacuna Pharma Pty Ltd

    Castration-Resistant Prostate Cancer

    phase 3 small molecule active

    1 trial

  3. ARO-APOC3 PFS

    Arrowhead Pharmaceuticals Ireland Limited

    Hypertriglyceridemia (HTG)

    phase 3 small molecule active

    1 trial

  4. ARO-APOC3 PFS, Plozasiran Injection Placebo

    Arrowhead Pharmaceuticals Ireland Limited

    Hypertriglyceridemia

    phase 3 small molecule active

    1 trial

  5. ARO-APOC3 PFS, Plozasiran Injection Placebo

    Arrowhead Pharmaceuticals Ireland Limited

    Severe hypertriglyceridemia (SHTG)

    phase 3 small molecule active

    1 trial

  6. AROAPOC3-3001

    Arrowhead Pharmaceuticals Ireland Limited

    Familial Chylomicronemia Syndrome (FCS)

    phase 3 small molecule active

    1 trial

  7. ARQ-151 0.3% cream

    Arcutis Biotherapeutics

    Chronic Plaque Psoriasis

    phase 3 small molecule completed

    1 trial

  8. ARQ-151 Cream 0.15% or ARQ-151 Cream 0.05%

    Arcutis Biotherapeutics

    Atopic Dermatitis Eczema

    phase 3 small molecule completed

    1 trial

  9. ASC09F+Oseltamivir

    Tongji Hospital

    2019-nCoV Pneumonia

    phase 3 small molecule active

    1 trial

  10. ASCIMINIB HYDROCHLORIDE, ASCIMINIB

    Novartis Pharmaceuticals

    Chronic Myelogenous Leukemia in chronic phase (CML-CP)

    phase 3 small molecule active

    1 trial

  11. ASCs (Cx401, company code)

    Takeda

    Anal Fistula

    phase 3 small molecule completed

    1 trial

  12. ASND0035

    Ascendis Pharma Bone Diseases A/S

    Chronic hypoparathyroidism

    phase 3 small molecule active

    1 trial

  13. ASND0047

    Ascendis Pharma Endocrinology Division A/S

    Turner Syndrome (TS), idiopathic short stature (ISS), short stature homeobox containing gene deficiency (SHOX-D), small for gestational age (SGA)

    phase 3 small molecule active

    1 trial

  14. ASP8825

    Astellas Pharma Inc

    Restless Legs Syndrome

    phase 3 small molecule completed

    1 trial

  15. AST-120and pentoxyphylline (PTX)

    Hospital Authority, Hong Kong

    Acute Kidney Injury

    phase 3 small molecule active

    1 trial

  16. ASTX030-01

    Taiho Pharma Netherlands B.V.

    Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML)

    phase 3 small molecule active

    1 trial

  17. AT-01B-008

    Atea Pharmaceuticals

    Chronic Hepatitis C Virus (HCV) Infection

    phase 3 small molecule active

    1 trial

  18. AT132

    Astellas Pharma GmbH

    X-linked Myotubular Myopathy (XLMTM)

    phase 3 small molecule active

    1 trial

  19. AT148006

    Wuhan Createrna Science and Technology Co., Ltd

    Patients with HER2-overexpressing advanced or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma that has progressed on or after a prior HER2-directed agent and fluoropyrimidine- or platinum-containing chemotherapy (2nd-line or 3rd-line)

    phase 3 small molecule active

    1 trial

  20. AT2221

    AMICUS THERAPEUTICS PTY LTD

    Pompe Disease (Late-onset)

    phase 3 small molecule completed

    1 trial

  21. AT2221, ATB200

    AMICUS THERAPEUTICS PTY LTD

    Adult Subjects With Late Onset Pompe Disease (LOPD)

    phase 3 small molecule active

    1 trial

  22. ATLG

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hematopoietic Stem Cell Transplantation

    phase 3 small molecule active

    1 trial

  23. ATM-AVI

    Pfizer

    Complicated Intra-abdominal Infection

    phase 3 small molecule completed

    1 trial

  24. ATM-AVI

    Pfizer

    Serious Bacterial Infection

    phase 3 other terminated

    1 trial

  25. ATN-106

    Lacuna Pharma Pty Ltd

    Congenital antithrombin deficiency

    phase 3 small molecule active

    1 trial

  26. ATN-108

    Lacuna Pharma Pty Ltd

    Acquired Antithrombin Deficiency (Heparin Resistance)

    phase 3 small molecule active

    1 trial

  27. ATV

    Bristol-Myers Squibb

    HIV Infections

    phase 3 small molecule completed

    1 trial

  28. AU-011-301

    Aura Biosciences

    Primary Indeterminate Lesions or Small Choroidal Melanoma

    phase 3 small molecule active

    1 trial

  29. AUTOP 2

    ISTA Pharma Limited

    Bacterial vaginosis, High risk preterm birth pregnancy, Vaginal flora abnormalities

    phase 3 small molecule active

    1 trial

  30. AV-299-23-301

    Lacuna Pharma Pty Ltd

    Head and Neck Squamous Cell Carcinoma (HNSCC)

    phase 3 small molecule active

    1 trial

  31. AV-951-20-304

    Lacuna Pharma Pty Ltd

    Renal cell carcinoma

    phase 3 small molecule active

    1 trial

  32. AV001

    Lacuna Pharma Pty Ltd

    Post-surgical neuropathic pain

    phase 3 small molecule active

    1 trial

  33. AVP-786 matching placebo, AVP-786

    Otsuka Beijing Research Institute

    Agitation in Patients With Dementia of the Alzheimer's Type

    phase 3 small molecule active

    1 trial

  34. AXS-02

    Axsome Therapeutics

    Osteoarthritis, Knee

    phase 3 small molecule active

    1 trial

  35. AXS-02 (oral zoledronate)

    Axsome Therapeutics

    Complex Regional Pain Syndrome

    phase 3 small molecule active

    1 trial

  36. AXS-05

    Axsome Therapeutics

    Agitation in Patients With Dementia of the Alzheimer's Type

    phase 3 small molecule completed

    3 trials

  37. AXS-05

    Axsome Therapeutics

    Treatment Resistant Major Depressive Disorder

    phase 3 small molecule completed

    1 trial

  38. AXS-05

    Axsome Therapeutics

    Depression

    phase 3 small molecule completed

    1 trial

  39. AXS-05 (dextromethorphan and bupropion) oral tablets

    Axsome Therapeutics

    Major Depressive Disorder

    phase 3 small molecule completed

    1 trial

  40. AXS-05 (dextromethorphan-bupropion)

    Axsome Therapeutics

    Agitation in Patients With Dementia of the Alzheimer's Type

    phase 3 small molecule completed

    2 trials

  41. AXS-07

    Axsome Therapeutics

    Migraine

    phase 3 small molecule completed

    1 trial

  42. AXS-07 (MoSEIC meloxicam and rizatriptan)

    Axsome Therapeutics

    Migraine

    phase 3 small molecule completed

    2 trials

  43. AXS-07 (meloxicam-rizatriptan)

    Axsome Therapeutics

    Migraine

    phase 3 small molecule completed

    1 trial

  44. AXS-12 (Reboxetine)

    Axsome Therapeutics

    Narcolepsy

    phase 3 small molecule completed

    3 trials

  45. AXS-14 (Esreboxetine)

    Axsome Therapeutics

    Fibromyalgia

    phase 3 small molecule active

    1 trial

  46. AZD0780

    AstraZeneca

    Cardiovascular Disease

    phase 3 small molecule active

    1 trial

  47. AZD0780

    AstraZeneca

    Heterozygous Familial Hypercholesterolaemia

    phase 3 small molecule active

    1 trial

  48. AZD0780 Placebo, AZD0780

    AstraZeneca AB

    Heterozygous familial hypercholesterolaemia

    phase 3 small molecule active

    1 trial

Frequently asked questions

How many Phase III pipeline programs are in the directory?

5,427 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.