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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

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  1. Nabilone

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 2 small molecule terminated

    1 trial

  2. Nabiximols

    Jazz Pharmaceuticals Ireland Limited

    NMO Spectrum Disorder

    phase 2 small molecule terminated

    1 trial

  3. Nabiximols

    Jazz Pharmaceuticals Ireland Limited

    Glioblastoma

    phase 2 small molecule active

    1 trial

  4. Nadunolimab

    Coherus Oncology

    Metastatic Microsatellite Stable Colorectal Carcinoma

    phase 2 small molecule active

    1 trial

  5. Nalbuphine ER, Placebo - Nalbuphine ER, Nalbuphine ER

    Trevi Therapeutics

    Idiopathic Pulmonary Fibrosis (IPF)

    phase 2 small molecule active

    1 trial

  6. Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 small molecule completed

    3 trials

  7. Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol Dependence

    phase 2 small molecule completed

    1 trial

  8. Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    Stable Opioid Dependence

    phase 2 small molecule completed

    1 trial

  9. Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol-Related Disorders

    phase 2 small molecule completed

    3 trials

  10. Naltrexone (drug)

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 2 small molecule completed

    1 trial

  11. Naltrexone hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Obesity

    phase 2 small molecule active

    1 trial

  12. Namilumab

    Takeda

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial

  13. Namilumab

    Takeda

    Rheumatoid Arthritis

    phase 2 small molecule completed

    2 trials

  14. Namodenoson

    Can-Fite BioPharma

    NASH - Nonalcoholic Steatohepatitis

    phase 2 small molecule active

    1 trial

  15. Namodenoson 25mg

    Can-Fite BioPharma

    Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial

  16. Namodenoson, Matching placebo for namodenoson

    Can-Fite BioPharma

    Non-Alcoholic Steatohepatitis (NASH) with F1-3 fibrosis

    phase 2 small molecule active

    1 trial

  17. NanoDOX Hydrogel

    United Therapeutics Europe Ltd

    Orthopedic Trauma Wounds

    phase 2 small molecule terminated

    1 trial

  18. Naproxen

    Protalix BioTherapeutics

    Healthy Volunteers

    phase 2 small molecule completed

    1 trial

  19. Nasal Carbon Dioxide

    United Therapeutics Europe Ltd

    Migraine

    phase 2 small molecule terminated

    1 trial

  20. Natriumthiosulfat 25%

    Disc Medicine

    Raynaud’s phenomenon

    phase 2 small molecule active

    1 trial

  21. Natrunix

    XBiotech Germany GmbH

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  22. Natrunix 400 mg

    XBiotech Germany GmbH

    Rheumatoid Arthritis

    phase 2 mab active

    1 trial

  23. Natrunix with MTX placebo (+folate)

    XBiotech Germany GmbH

    Rheumatoid Arthritis

    phase 2 small molecule active

    1 trial

  24. Navigating my Journey program

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 other completed

    1 trial

  25. Navitoclax, Navitoclax, RUXOLITINIB

    AbbVie Deutschland GmbH & Co. KG

    Myelofibrosis

    phase 2 small molecule active

    1 trial

  26. Nebivolol Ophthalmic Suspension 1 Percent

    Summit Therapeutics

    Open-Angle Glaucoma

    phase 2 small molecule completed

    1 trial

  27. Nebulized IVX-0142

    Teva Pharma GmbH

    Asthma

    phase 2 small molecule completed

    1 trial

  28. Nefazodone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  29. Neflamapimod

    Lacuna Pharma Pty Ltd

    Dementia with Lewy Bodies (DLB)

    phase 2 small molecule active

    1 trial

  30. Nemolizumab

    Galderma Australia Pty Ltd

    Atopic Dermatitis

    phase 2 small molecule active

    1 trial

  31. Nemtabrutinib, Nemtabrutinib, Nemtabrutinib, Nemtabrutinib, FLUDEOXYGLUCOSE (18F)

    Merck Sharp and Dohme

    Chronic lymphocytic leukemia/Small lymphocytic lymphoma; Richters transformation; Mantle cell lymphoma, Marginal zone lymphoma; Follicular lymphoma; Waldenström’s macroglobulinemia

    phase 2 small molecule active

    1 trial

  32. Nemtabrutinib, Zilovertamab vedotin, Nemtabrutinib, Nemtabrutinib, Nemtabrutinib

    Merck Sharp and Dohme

    Aggressive and Indolent B-cell Malignancies (mantle cell lymphoma; chronic lymphocytic leukemia; follicular lymphoma; Richter’s syndrome)

    phase 2 small molecule active

    1 trial

  33. Nenocorilant 200 mg

    CORCEPT THERAPEUTICS INC

    Neoplasms

    phase 2 small molecule active

    1 trial

  34. Neoadjuvant Chemotherapy

    Xiangya Hospital of Central South University

    High-Grade Upper Tract Urothelial Carcinoma

    phase 2 small molecule completed

    1 trial

  35. Neoadjuvant Chemotherapy (NACT)

    The First People's Hospital of Lianyungang

    HR+/HER2- Breast Cancer

    phase 2 small molecule active

    1 trial

  36. Neoadjuvant Chemotherapy combined with Neoadjuvant Radiotherapy

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 other active

    1 trial

  37. Neoadjuvant Sugemalimab + Chemotherapy Followed by Adjuvant Sugemalimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  38. Neoadjuvant Therapy

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 2 other active

    1 trial

  39. Neoadjuvant therapy: TCbHPy

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 other active

    1 trial

  40. Neoantigen specific TCR-T cell drug product

    Alaunos Therapeutics

    Gynecologic Cancer

    phase 2 mab terminated

    1 trial

  41. Nepicastat

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial

  42. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Solid Tumor, Adult

    phase 2 small molecule active

    1 trial

  43. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

    phase 2 small molecule terminated

    1 trial

  44. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Triple Negative Breast Cancer

    phase 2 small molecule active

    1 trial

  45. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Metastatic Prostate Adenocarcinoma

    phase 2 small molecule terminated

    1 trial

  46. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Anatomic Stage I Breast Cancer

    phase 2 small molecule active

    1 trial

  47. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Early-stage Breast Cancer

    phase 2 small molecule active

    1 trial

  48. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Early Stage HER2+ Breast Cancer

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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