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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

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  1. N-acetylcysteine

    Ultragenyx UK Limited

    Gaucher Disease Type 1

    phase 2 small molecule completed

    1 trial

  2. N-acetylcysteine (NAC)

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 small molecule completed

    1 trial

  3. N-acetylcysteine capsule

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  4. N-methyl glycine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Obsessive Compulsive Disorder

    phase 2 small molecule completed

    1 trial

  5. NAL ER

    Trevi Therapeutics

    Refractory Chronic Cough

    phase 2 small molecule completed

    1 trial

  6. NAL ER

    Trevi Therapeutics

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    3 trials

  7. NALIRIFOX+Adebrelimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pancreatic Ductal Adenocarcinoma (PDAC)

    phase 2 small molecule active

    1 trial

  8. NANOBODY® Placebo; The placebo is a standard placebo formulation containing common excipients for NANOBODY drug products and is used by Sanofi for NANOBODY clinical studies., SAR442970

    Sanofi-aventis Healthcare Pty Ltd

    Crohn’s disease

    phase 2 small molecule active

    1 trial

  9. NAP (Naptumomab estafenatox)

    BRIGHT MINDS BIOSCIENCES INC.

    Non-small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial

  10. NAPROXEN SODIUM, DESOGESTREL, TRAMADOL HYDROCHLORIDE, IBUPROFEN, Placebo to match AMY109, Placebo to match desogestrel, Feanolla 75 microgram film-coated tablets, CODEINE PHOSPHATE, PARACETAMOL, NAPROXEN, AMY109

    Lacuna Pharma Pty Ltd

    Endometriosis

    phase 2 small molecule active

    1 trial

  11. NAT01, NAT03, Placebo film coated tablets, NAT02

    Dr. Falk Pharma GmbH

    Idiopathic or Diabetic Gastroparesis

    phase 2 small molecule active

    1 trial

  12. NBI-1065890

    NEUROCRINE BIOSCIENCES INC

    Tardive Dyskinesia

    phase 2 small molecule active

    1 trial

  13. NBI-1070770

    NEUROCRINE BIOSCIENCES INC

    Major Depressive Disorder

    phase 2 small molecule completed

    1 trial

  14. NBI-1117568

    NEUROCRINE BIOSCIENCES INC

    Bipolar I Disorder

    phase 2 small molecule active

    1 trial

  15. NBI-1117570

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia

    phase 2 small molecule active

    1 trial

  16. NBI-1117570, NBI-1117570, Placebo for nbi-1117570

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia

    phase 2 small molecule active

    1 trial

  17. NBI-5788

    NEUROCRINE BIOSCIENCES INC

    Multiple Sclerosis

    phase 2 small molecule completed

    1 trial

  18. NBI-74788

    NEUROCRINE BIOSCIENCES INC

    Congenital adrenal hyperplasia (CAH)

    phase 2 small molecule active

    1 trial

  19. NBI-74788

    NEUROCRINE BIOSCIENCES INC

    CAH - Congenital Adrenal Hyperplasia

    phase 2 small molecule completed

    1 trial

  20. NBI-827104

    NEUROCRINE BIOSCIENCES INC

    Epileptic Encephalopathy

    phase 2 small molecule terminated

    2 trials

  21. NBI-827104

    NEUROCRINE BIOSCIENCES INC

    Essential Tremor

    phase 2 small molecule completed

    1 trial

  22. NBI-921352

    NEUROCRINE BIOSCIENCES INC

    Focal Onset Seizure

    phase 2 small molecule completed

    2 trials

  23. NBI-921352

    NEUROCRINE BIOSCIENCES INC

    SCN8A Developmental and Epileptic Encephalopathy Syndrome

    phase 2 small molecule active

    2 trials

  24. NBI-98854

    NEUROCRINE BIOSCIENCES INC

    Tourette Syndrome

    phase 2 small molecule terminated

    4 trials

  25. NBP Softgel Capsules

    NovaBridge Biosciences

    AIS

    phase 2 small molecule completed

    1 trial

  26. NBS10

    LISATA THERAPEUTICS, INC.

    ST Segment Elevation Myocardial Infarction

    phase 2 mab completed

    1 trial

  27. NDI-034858

    Takeda

    Psoriatic Arthritis

    phase 2 small molecule completed

    1 trial

  28. NDI-034858 study drug

    Takeda

    Moderate to Severe Plaque Psoriasis

    phase 2 small molecule completed

    1 trial

  29. NDV01 intravesical controlled release formulation of gemcitabine and docetaxel

    RELMADA THERAPEUTICS, INC.

    Non Muscle Invasive Bladder Cancer

    phase 2 small molecule active

    1 trial

  30. NEO-201 in combination with pembrolizumab

    Chongqing Precision Biotech Co., Ltd

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  31. NERATINIB

    PUMA BIOTECHNOLOGY, INC.

    Stage IV (Metastatic) Breast Cancer

    phase 2 small molecule terminated

    1 trial

  32. NERATINIB, Sindiar 2 mg cápsulas duras

    Ningbo Cancer Hospital

    HER2 positive (HER2+), Hormone Receptor positive (HR+) Early-stage Breast Cancer.

    phase 2 small molecule active

    1 trial

  33. NEXPOVIO 20 mg film-coated tablets, HOLOXAN 1 g polvere per soluzione per infusione, Decadron “8 mg/2 ml Soluzione iniettabile”, ETOPOSIDE TEVA 20 mg/ml, concentrato per soluzione per infusione.

    Fondazione Telethon ETS

    Relapsed or Refractory Peripheral T-cell Lymphomas

    phase 2 small molecule active

    1 trial

  34. NIMOTUZUMAB, NAVELBINE 10 mg/ml concentrato per soluzione per infusione

    Fondazione Telethon ETS

    Diffuse intrinsic pontine glioma

    phase 2 small molecule active

    1 trial

  35. NIVOLUMAB

    Disc Medicine

    Peritoneal Mesothelioma

    phase 2 small molecule active

    1 trial

  36. NIVOLUMAB, BT5528

    BICYCLE THERAPEUTICS

    Advanced Malignancies Associated with EphA2 Expression

    phase 2 small molecule active

    1 trial

  37. NIVOLUMAB, TEDOPI

    Fondazione Telethon ETS

    metastatic non-small-cell lung cancer

    phase 2 small molecule active

    1 trial

  38. NK cell and PD-1 antibody

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 other completed

    1 trial

  39. NK cell perfusion group

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Abortion, Missed

    phase 2 mab active

    1 trial

  40. NK cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma

    phase 2 mab active

    1 trial

  41. NK cells

    Hospital Authority, Hong Kong

    Hepatocellular Carcinoma

    phase 2 mab active

    1 trial

  42. NKTR-102

    Nektar Therapeutics UK Limited

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial

  43. NKTR-102

    Nektar Therapeutics UK Limited

    Tumor

    phase 2 small molecule completed

    1 trial

  44. NKTR-102 100 mg/m2

    Nektar Therapeutics UK Limited

    Tumor

    phase 2 small molecule completed

    1 trial

  45. NKTR-102 145 mg/m2

    Nektar Therapeutics UK Limited

    Malignant Solid Tumor

    phase 2 small molecule completed

    1 trial

  46. NKTR-102 q14d

    Nektar Therapeutics UK Limited

    Tumor

    phase 2 small molecule completed

    1 trial

  47. NKTR-181

    Nektar Therapeutics UK Limited

    Osteoarthritis of the Knee

    phase 2 small molecule completed

    1 trial

  48. NKTR-214

    Nektar Therapeutics UK Limited

    Non-Small Cell Lung Cancer

    phase 2 small molecule terminated

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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