Intelligence Β· Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Zimberelimab

    Arcus Biosciences

    Adenocarcinoma Stomach

    phase 2 small molecule terminated

    1 trial
  2. Zimberelimab (ZIM)

    Arcus Biosciences

    Lung Cancer

    phase 2 small molecule active

    1 trial
  3. Zimberelimab, Trodelvy 200 mg powder for concentrate for solution for infusion

    Fondazione Telethon ETS

    Muscle-Invasive Bladder cancer

    phase 2 small molecule active

    1 trial
  4. Zirabev 25 mg/ml concentrate for solution for infusion, SAR445877, Erbitux 5 mg/mL solution for infusion, Zirabev 25 mg/ml concentrate for solution for infusion

    Sanofi-aventis Healthcare Pty Ltd

    Solid tumor

    phase 2 small molecule active

    1 trial
  5. Zirconium Zr 89 Girentuximab

    Telix Innovations

    Clear Cell Renal Cell Carcinoma

    phase 2 small molecule active

    1 trial
  6. Ziv-Aflibercept

    Regeneron UK Limited

    Uveal Melanoma

    phase 2 mab terminated

    1 trial
  7. Zn-Telomir

    Telomir Pharmaceuticals

    Triple-Negative Breast Cancer (TNBC)

    phase 2 small molecule active

    1 trial
  8. Zoladex

    The First People's Hospital of Lianyungang

    Prostate Cancer

    phase 2 small molecule active

    1 trial
  9. Zonisamide

    United Therapeutics Europe Ltd

    Alcohol Dependence

    phase 2 small molecule completed

    1 trial
  10. Zonisamide 100Mg Cap

    United Therapeutics Europe Ltd

    Hearing Loss, Noise-Induced

    phase 2 small molecule terminated

    2 trials
  11. Zopiclone

    The First People's Hospital of Lianyungang

    Insomnia Chronic

    phase 2 small molecule completed

    1 trial
  12. Zr89

    Disc Medicine

    giant cell arteritis, rheumatoid arthritis

    phase 2 small molecule active

    1 trial
  13. Zuberitamab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HSCT

    phase 2 small molecule active

    1 trial
  14. Zumsemetinib

    Aclaris Therapeutics

    Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer

    phase 2 small molecule active

    1 trial
  15. Zydena (Udenafil)

    Samsung Bioepis NL B.V.

    Vascular Dementia

    phase 2 small molecule active

    1 trial
  16. [11C]CPPC PET ligand

    United Therapeutics Europe Ltd

    ALS

    phase 2 small molecule active

    1 trial
  17. [123I] 5-IA

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial
  18. [123I]B-CIT

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial
  19. [123I]Ξ²-CIT

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule active

    1 trial
  20. [177Lu]-NeoB solution for infusion, AAA503

    Advanced Accelerator Applications

    Solid tumors known to overexpress GRPR and with [68Ga]-NeoB lesion uptake.

    phase 2 small molecule active

    1 trial
  21. [18F]-olaparib PET; Molecular imaging of DNA damage response by [18F]-olaparib PET

    Disc Medicine

    Head and neck squamous cell carcinoma (HNSCC)

    phase 2 other active

    1 trial
  22. [18F]Fluor-PEG-Folate

    Disc Medicine

    giant cell arteritis

    phase 2 small molecule active

    1 trial
  23. [18F]PI-2620

    The George Institute

    Down Syndrome., AlzheimerΒ΄s Disease.

    phase 2 small molecule active

    1 trial
  24. [18F]PI-2620

    The George Institute

    Down Syndrome, Alzheimer disease

    phase 2 small molecule active

    1 trial
  25. [18F]PI-2620

    The George Institute

    Progressive supranuclear palsy, Parkinson's disease

    phase 2 small molecule active

    1 trial
  26. [18F]Tetrafluoroborate

    Disc Medicine

    Differentiated Thyroid Cancer

    phase 2 small molecule active

    1 trial
  27. [203Pb]Pb-PSV359

    Perspective Therapeutics

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial
  28. [203Pb]VMT-Ξ±-NET

    Perspective Therapeutics

    Neuroendocrine Tumors Unresectable

    phase 2 small molecule active

    1 trial
  29. [203Pb]VMT01

    Perspective Therapeutics

    Recurrent Melanoma (Skin)

    phase 2 small molecule active

    1 trial
  30. [6,6-2H2]glucose

    Ultragenyx UK Limited

    Glycogen Storage Disease Type IA

    phase 2 mab completed

    1 trial
  31. [68Ga]BED003 injection

    Blue Earth Diagnostics Ireland Ltd

    Colorectal cancer (CRC), gastric cancer (GC), pancreatic ductal adenocarcinoma (PDAC), invasive lobular breast cancer (ILC), and epithelial ovarian cancer (EOC).

    phase 2 small molecule active

    1 trial
  32. [68Ga]FAPI-46

    Disc Medicine

    giant cell arteritis - polymyalgia rheumatica spectrum disease

    phase 2 small molecule active

    1 trial
  33. [68Ga]Ga-PentixaFor

    Disc Medicine

    Cardiac Sarcoidosis

    phase 2 small molecule active

    1 trial
  34. [90Y]Y-PentixaTher, LysaKare 25 g/25 g solution for infusion, [68Ga]Ga-PentixaFor

    Alphapharm Pty Ltd

    Central nervous system (CNS) lymphoma; recurrent or refractory primary or isolated secondary

    phase 2 small molecule active

    1 trial
  35. a standardized physical therapy program

    Hospital Authority, Hong Kong

    Frozen Shoulder

    phase 2 other completed

    1 trial
  36. abituzumab

    United Therapeutics Europe Ltd

    Metastatic Colorectal Cancer

    phase 2 small molecule terminated

    1 trial
  37. accelerated intermittent theta burst stimulation

    United Therapeutics Europe Ltd

    Long COVID

    phase 2 other active

    1 trial
  38. acetylsalicylic acid

    Protalix BioTherapeutics

    Upper Gastrointestinal Mucosal Damage

    phase 2 small molecule completed

    1 trial
  39. activated recombinant human factor VII

    Novo Nordisk A/S

    Acquired Bleeding Disorder

    phase 2 small molecule completed

    2 trials
  40. acupuncture

    Hospital Authority, Hong Kong

    Peripheral Neuropathy Grade 2 or Greater

    phase 2 other terminated

    1 trial
  41. aerobic exercise

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 other completed

    1 trial
  42. aerosolized vancomycin or gentamicin

    Nektar Therapeutics UK Limited

    Ventilator Associated Pneumonia

    phase 2 small molecule completed

    1 trial
  43. affect regulation training

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 other completed

    1 trial
  44. aflibercept

    Regeneron UK Limited

    Neovascular (Wet) Age-Related Macular Degeneration

    phase 2 small molecule completed

    1 trial
  45. aflibercept + FOLFIRI

    Regeneron UK Limited

    Metastatic Colorectal Cancer

    phase 2 small molecule terminated

    1 trial
  46. aflibercept injection (VEGF Trap-Eye, BAY86-5321)

    Regeneron UK Limited

    Macular Degeneration

    phase 2 mab completed

    1 trial
  47. aglatimagene besadenovec

    Candel Therapeutics

    Prostate Cancer

    phase 2 mab active

    1 trial
  48. aglatimagene besadenovec + valacyclovir

    Candel Therapeutics

    Prostate Cancer Patients Treated by Radiotherapy

    phase 2 mab active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources Β· All pipeline programs