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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. XPF-002

    Xenon Pharmaceuticals

    Postherpetic Neuralgia

    phase 2 small molecule completed

    1 trial

  2. XPF-005

    Xenon Pharmaceuticals

    Acne Vulgaris

    phase 2 small molecule completed

    1 trial

  3. XPF-010, XPF-008, XEN1101 placebo

    Xenon Pharmaceuticals

    Adult focal (partial onset) epilepsy

    phase 2 small molecule active

    1 trial

  4. XTX202

    Xilio Therapeutics

    Advanced Solid Tumor

    phase 2 small molecule completed

    1 trial

  5. XTX301

    Xilio Therapeutics

    Advanced Solid Tumor

    phase 2 small molecule active

    1 trial

  6. Xanthohumol

    NORTHWEST BIOTHERAPEUTICS INC

    Crohn Disease

    phase 2 small molecule active

    1 trial

  7. Xarelto 2.5 mg film-coated tablets

    Tour Hekla

    Chronic hemodialysis

    phase 2 small molecule active

    1 trial

  8. Xeloda 150 mg film-coated tablets, ELOXATINE 5 mg/ml, solution à diluer pour perfusion, Folinic acid (as calcium folinate) 10 mg/ml solution for injection/infusion, ELVORINE 100 mg/10 mL, solution injectable, FLUOROURACILE TEVA 1000 mg/20 ml, solution à diluer pour perfusion

    CERO THERAPEUTICS HOLDINGS, INC.

    colon cancer

    phase 2 small molecule active

    1 trial

  9. Xeloda 150 mg film-coated tablets, Folinic acid (as calcium folinate) 10 mg/ml solution for injection/infusion, ELOXATINE 5 mg/ml, solution à diluer pour perfusion, Vectibix 20 mg/ml concentrate for solution for infusion, FLUOROURACILE TEVA 1000 mg/20 ml, solution à diluer pour perfusion

    CERO THERAPEUTICS HOLDINGS, INC.

    metastatic colorectal adenocarcinoma

    phase 2 small molecule active

    1 trial

  10. Xeloda 150 mg film-coated tablets, Xeloda 500 mg film-coated tablets, Paclitaxel 6 mg/mL concentrate for solution for infusion, Herceptin 150 mg powder for concentrate for solution for infusion, GEMZAR 200 mg, poudre pour solution pour perfusion, HALAVEN 0.44 mg/ml solution for injection, Vinorelbine 10 mg/ml concentrate for solution for infusion, GEMZAR 1000 mg, poudre pour solution pour perfusion, evorpacept, HALAVEN 0.44 mg/ml solution for injection

    ALX ONCOLOGY HOLDINGS INC

    Breast Cancer

    phase 2 small molecule active

    1 trial

  11. Xenpozyme (olipudase alfa,GZ402665)

    Sanofi Winthrop Industrie

    Niemann-Pick disease

    phase 2 small molecule active

    1 trial

  12. Xofigo 1100 kBq/mL solution for injection, DELTACORTENE 5 mg compresse, Decadron “4 mg/1 ml Soluzione iniettabile”, Docetaxel Accord 20 mg/1 ml concentrate for solution for infusion, SOLDESAM 0,2% gocce orali, soluzione

    Istituto Gentili S.r.l.

    metastatic castration resistant prostate cancer (mCRPC), symptomatic bone-only metastatic castration resistant prostate cancer (mCRPC)

    phase 2 small molecule active

    1 trial

  13. Xospata 40 mg film-coated tablets

    Wuhan Createrna Science and Technology Co., Ltd

    Acute myeloid leukaemia, Acute myeloid leukaemia

    phase 2 small molecule active

    1 trial

  14. Xospata 40 mg film-coated tablets

    Fondazione Telethon ETS

    newly diagnosed non-M3 FLT3-positive acute myeloid leukemia

    phase 2 small molecule active

    1 trial

  15. Xyrem (sodium oxybate) oral solution

    Jazz Pharmaceuticals Ireland Limited

    Fibromyalgia

    phase 2 small molecule completed

    1 trial

  16. YERVOY 5 mg/ml concentrate for solution for infusion, KEYTRUDA 25 mg/mL concentrate for solution for infusion, KIMMTRAK 100 micrograms/0.5 mL concentrate for solution for infusion, DACARBAZINE

    Immunocore Ireland Limited

    Previously untreated advanced uveal melanoma (UM)

    phase 2 small molecule active

    1 trial

  17. YERVOY 5 mg/ml concentrate for solution for infusion, OPDIVO 10 mg/mL concentrate for solution for infusion.

    Disc Medicine

    castration-resistant prostate cancer

    phase 2 small molecule active

    1 trial

  18. YERVOY 5 mg/ml concentrate for solution for infusion, OPDIVO 10 mg/mL concentrate for solution for infusion.

    The George Institute

    melanoma brain metastases

    phase 2 small molecule active

    1 trial

  19. YESCARTA 0.4 – 2 x 10e8 cells dispersion for infusion, Tecartus 0.4 - 2 x 10e8 cells dispersion for infusion, KITE-363

    Lacuna Pharma Pty Ltd

    Solid and Hematological Malignancies

    phase 2 small molecule active

    1 trial

  20. YM150

    Astellas Pharma Inc

    Thromboembolism

    phase 2 small molecule completed

    1 trial

  21. YMSM

    BRIGHT MINDS BIOSCIENCES INC.

    Behavior

    phase 2 other completed

    1 trial

  22. YPEG-rhEPO

    The First People's Hospital of Lianyungang

    Renal Anemia of Chronic Kidney Disease

    phase 2 small molecule completed

    1 trial

  23. YTB323, CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, TOCILIZUMAB

    Novartis Pharmaceuticals

    Non-active Progressive Multiple Sclerosis (PMS)

    phase 2 small molecule active

    1 trial

  24. YTB323, Flebogamma DIF 50 mg/ml solution for infusion, TOCILIZUMAB, FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE

    Novartis Pharmaceuticals

    Treatment-resistant generalized Myasthenia Gravis

    phase 2 small molecule active

    1 trial

  25. Yi Qi Yang Yin Decoction

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary Sjögren Syndrome

    phase 2 small molecule active

    1 trial

  26. Yigansan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Tourette Disorder

    phase 2 small molecule completed

    1 trial

  27. Yogurt smoothie with BB-12

    United Therapeutics Europe Ltd

    Metabolic Syndrome

    phase 2 small molecule active

    1 trial

  28. Yondelis 1 mg powder for concentrate for solution for infusion, DOXORUBICINE ARROW 2 mg/ml, solution pour perfusion

    Ningbo Cancer Hospital

    Localized, resected, FIGO stage I (2018 classification), uterine leiomyosarcoma

    phase 2 small molecule active

    1 trial

  29. Yougui granules

    The First People's Hospital of Lianyungang

    Renal Insufficiency, Chronic

    phase 2 small molecule terminated

    1 trial

  30. Z-Endoxifen

    ATOSSA THERAPEUTICS, INC.

    Breast Density

    phase 2 small molecule completed

    1 trial

  31. Z650

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule completed

    1 trial

  32. ZADAXIN® 1,6 mg/ml

    Lacuna Pharma Pty Ltd

    Cystic Fibrosis

    phase 2 small molecule active

    1 trial

  33. ZASOCITINIB

    Takeda

    Moderate to Severely Active Ulcerative Colitis & Moderate to Severely Active Crohn's Disease

    phase 2 small molecule active

    1 trial

  34. ZASOCITINIB, Matching Placebo for TAK-279

    Takeda

    Hidradenitis Suppurativa

    phase 2 small molecule active

    1 trial

  35. ZASOCITINIB, ZASOCITINIB, White opaque, hard hypromellose capsule, size 3 containing same excipients as TAK-279 active capsule

    Takeda

    Non-segmental vitiligo

    phase 2 small molecule active

    1 trial

  36. ZD6474

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 2 small molecule completed

    2 trials

  37. ZED1227 + SIGE

    Takeda

    Celiac Disease

    phase 2 small molecule active

    1 trial

  38. ZENGAC “500 mg Polvere per soluzione per infusione e per uso orale”, Plenvu, polvere per soluzione orale, SELG ESSE polvere per soluzione orale, Avastin 25 mg/ml concentrate for solution for infusion., Tecentriq 1 200 mg concentrate for solution for infusion, Vancomicina Mylan 500 mg polvere per soluzione per infusione

    Istituto Gentili S.r.l.

    unresectable hepatocellular carcinoma (HCC)

    phase 2 small molecule active

    1 trial

  39. ZEULIDE 3,75 mg, poudre et solvant pour suspension injectable à libération prolongée, Elacestrant

    The George Institute

    Breast cancer

    phase 2 small molecule active

    1 trial

  40. ZG005

    Suzhou Zelgen Biopharmaceuticals Co.,Ltd

    Biliary Tract Carcinoma

    phase 2 small molecule active

    1 trial

  41. ZIMBERELIMAB

    Arcus Biosciences

    Pancreatic Cancer

    phase 2 small molecule on hold

    1 trial

  42. ZIO-101 (Darinaparsin)

    Alaunos Therapeutics

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  43. ZIO-201

    Alaunos Therapeutics

    Advanced Sarcoma

    phase 2 small molecule completed

    1 trial

  44. ZIV-Aflibercept

    Regeneron UK Limited

    Metastatic Uveal Melanoma

    phase 2 small molecule active

    1 trial

  45. ZL-1102 1% w/w gel BID for 16 weeks

    Hong Kong Baptist University

    Plaque Psoriasis

    phase 2 small molecule active

    1 trial

  46. ZN-d5

    Zentalis Pharmaceuticals

    Amyloidosis

    phase 2 small molecule completed

    1 trial

  47. ZN-d5 ZN-c3

    Zentalis Pharmaceuticals

    Acute Myeloid Leukemia (AML)

    phase 2 small molecule terminated

    1 trial

  48. ZW25 (Zanidatamab)

    Jazz Pharmaceuticals Ireland Limited

    HER2+/HR+ Breast Cancer

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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