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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. RC48- ADC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cance

    phase 2 small molecule active

    1 trial

  2. RC48-ADC

    Chinese University of Hong Kong

    Muscle Invasive Bladder Carcinoma

    phase 2 small molecule active

    1 trial

  3. RD14-01

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Solid Tumor

    phase 2 mab active

    1 trial

  4. RE-021 (Sparsentan)

    Travere Therapeutics

    Focal Segmental Glomerulosclerosis

    phase 2 small molecule completed

    1 trial

  5. REC-1245

    RECURSION PHARMACEUTICALS, INC.

    Unresectable

    phase 2 small molecule active

    1 trial

  6. REC-3964

    RECURSION PHARMACEUTICALS, INC.

    Recurrent Clostridioides Difficile Infection

    phase 2 small molecule terminated

    1 trial

  7. REC-4881

    RECURSION PHARMACEUTICALS, INC.

    Familial Adenomatous Polyposis

    phase 2 small molecule active

    1 trial

  8. REC-4881

    RECURSION PHARMACEUTICALS, INC.

    AXIN1 Gene Mutation

    phase 2 small molecule terminated

    1 trial

  9. REC-994

    RECURSION PHARMACEUTICALS, INC.

    Cerebral Cavernous Malformation

    phase 2 small molecule completed

    1 trial

  10. RECOMBINANT ADAMTS13 (rADAMTS13), -, RITUXIMAB

    Takeda

    Immune-mediated thrombotic thrombocytopenic purpura (iTTP)

    phase 2 small molecule active

    1 trial

  11. REGEND001 cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule completed

    1 trial

  12. REGN1033 (SAR391786)

    Regeneron UK Limited

    Sarcopenia

    phase 2 small molecule completed

    1 trial

  13. REGN10597

    Regeneron UK Limited

    Melanoma

    phase 2 small molecule active

    1 trial

  14. REGN10933+REGN10987 combination therapy

    Regeneron UK Limited

    COVID-19

    phase 2 small molecule completed

    2 trials

  15. REGN13335

    Regeneron UK Limited

    Pulmonary Arterial Hypertension (PAH)

    phase 2 small molecule active

    1 trial

  16. REGN13335, Placebo to REGN13335, REGN13335

    Lacuna Pharma Pty Ltd

    Pulmonary Arterial Hypertension (PAH)

    phase 2 small molecule active

    1 trial

  17. REGN14256

    Regeneron UK Limited

    SARS-CoV-2

    phase 2 small molecule terminated

    1 trial

  18. REGN1500 250 mg SC/15 mg/kg IV/450 mg SC

    Regeneron UK Limited

    Homozygous Familial Hypercholesterolemia

    phase 2 small molecule completed

    1 trial

  19. REGN15505

    Regeneron UK Limited

    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

    phase 2 small molecule active

    1 trial

  20. REGN1908-1909

    Regeneron UK Limited

    Cat Allergy

    phase 2 small molecule completed

    1 trial

  21. REGN2176-3

    Regeneron UK Limited

    Neovascular Age-Related Macular Degeneration

    phase 2 small molecule terminated

    1 trial

  22. REGN2477

    Regeneron UK Limited

    Fibrodysplasia Ossificans Progressiva

    phase 2 small molecule completed

    1 trial

  23. REGN2477+REGN1033

    Regeneron UK Limited

    Sporadic Inclusion Body Myositis

    phase 2 small molecule terminated

    1 trial

  24. REGN2810

    Regeneron UK Limited

    Prostate Cancer Metastatic

    phase 2 small molecule active

    1 trial

  25. REGN3500

    Regeneron UK Limited

    Atopic Dermatitis

    phase 2 small molecule terminated

    2 trials

  26. REGN3918

    Regeneron UK Limited

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    phase 2 small molecule completed

    1 trial

  27. REGN4336

    Regeneron UK Limited

    Metastatic Castration-resistant Prostate Cancer

    phase 2 small molecule active

    1 trial

  28. REGN4461

    Regeneron UK Limited

    Familial Partial Lipodystrophy

    phase 2 small molecule terminated

    1 trial

  29. REGN475

    Regeneron UK Limited

    Osteoarthritis

    phase 2 mab terminated

    1 trial

  30. REGN475

    Regeneron UK Limited

    Osteoarthritis of the Knee

    phase 2 small molecule completed

    1 trial

  31. REGN475

    Regeneron UK Limited

    Sciatica

    phase 2 small molecule completed

    1 trial

  32. REGN475/SAR164877

    Regeneron UK Limited

    Back Pain

    phase 2 small molecule terminated

    1 trial

  33. REGN475/SAR164877

    Regeneron UK Limited

    Abdominal Pain Upper

    phase 2 small molecule terminated

    1 trial

  34. REGN5069

    Regeneron UK Limited

    Osteoarthritis of the Knee

    phase 2 small molecule terminated

    1 trial

  35. REGN5093

    Lacuna Pharma Pty Ltd

    MET-altered non-small cell lung cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  36. REGN5093

    Regeneron UK Limited

    NSCLC

    phase 2 small molecule active

    1 trial

  37. REGN5381

    Regeneron UK Limited

    Heart Failure

    phase 2 small molecule terminated

    2 trials

  38. REGN5381

    Regeneron UK Limited

    Uncontrolled Hypertension

    phase 2 small molecule terminated

    1 trial

  39. REGN5459

    Regeneron UK Limited

    Relapsed Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  40. REGN5668

    Regeneron UK Limited

    Ovarian Cancer

    phase 2 small molecule active

    1 trial

  41. REGN5678

    Regeneron UK Limited

    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

    phase 2 small molecule active

    1 trial

  42. REGN7041

    Regeneron UK Limited

    Active Noninfectious Uveitis Affecting the Posterior Segment

    phase 2 small molecule active

    1 trial

  43. REGN7041

    Lacuna Pharma Pty Ltd

    Noninfectious Uveitis

    phase 2 small molecule active

    1 trial

  44. REGN7075

    Regeneron UK Limited

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  45. REGN7257

    Lacuna Pharma Pty Ltd

    Severe aplastic anemia (SAA)

    phase 2 small molecule active

    1 trial

  46. REGN7508

    Regeneron UK Limited

    Venous Thromboembolism

    phase 2 small molecule completed

    1 trial

  47. REGN7544

    Regeneron UK Limited

    Sepsis-Induced Hypotension

    phase 2 small molecule completed

    1 trial

  48. REGN7544

    Regeneron UK Limited

    Postural Orthostatic Tachycardia Syndrome (POTS)

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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