Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Page 103 of 151

  1. Placebo to match LY, Mirikizumab, Placebo to Mirikizumab, Mirikizumab

    Eli Lilly Co.

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial
  2. Placebo to match LY3540378

    Eli Lilly Co.

    Heart Failure with Preserved Ejection Fraction, Heart Failure

    phase 2 small molecule active

    1 trial
  3. Placebo to match LY3556050

    Eli Lilly Co.

    Diabetic Peripheral Neuropathy

    phase 2 small molecule active

    1 trial
  4. Placebo to match LY3848575

    Eli Lilly Co.

    Neuropathic Pain; Distal Sensory Polyneuropathy

    phase 2 small molecule active

    1 trial
  5. Placebo to match buloxibutid oral capsules, Buloxibutid

    Lacuna Pharma Pty Ltd

    idiopathic pulmonary fibrosis

    phase 2 small molecule active

    1 trial
  6. Placebo transplantation

    Chinese Academy of Sciences

    Primary Ovarian Insufficiency

    phase 2 mab active

    1 trial
  7. Placebo vials contain 4.5 ml of storage solution only (2.5 ml albumin 20%, 1.1 ml normal saline solution, 0.45 ml Citrate dextrose solution, 0.45 ml Dimethyl sulfoxide). Placebo and MSC vials are indistinguishable in appearance after thawing. There are no observable differences between treatments that could potentially compromise the blind., Mesenchymal stromal cells

    Fondazione Telethon ETS

    Traumatic Brain Injury

    phase 2 small molecule active

    1 trial
  8. Placebo, APG777

    Apogee Therapeutics

    Atopic Dermatitis

    phase 2 small molecule active

    1 trial
  9. Placebo, BFB759

    Blue Earth Diagnostics Ireland Ltd

    Hidradenitis Suppurativa

    phase 2 small molecule active

    1 trial
  10. Placebo, EP262, -, EP262

    Lacuna Pharma Pty Ltd

    Chronic Spontaneous Urticaria

    phase 2 small molecule active

    1 trial
  11. Placebo, GLUCOPHAGE 500 mg tabletki powlekane

    Bial Portela & Companhia S.A.

    idiopathic infertility

    phase 2 small molecule active

    1 trial
  12. Placebo, Vacuna Phleum pratense 3000 TBU/ml, Vacuna Phleum pratense 1000 TBU/ml, Test de provocación nasal Phleum pratense, Vacuna Phleum pratense 6000 TBU/ml

    Lacuna Pharma Pty Ltd

    Allergic rhinitis/rhinoconjunctivitis caused by grass polen allergy

    phase 2 small molecule active

    1 trial
  13. Placebo: Normal Saline - Solution for injection, Daxdilimab

    Elan Pharma International

    Primary Discoid Lupus Erythematosus

    phase 2 small molecule active

    1 trial
  14. Placebos

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 2 small molecule completed

    1 trial
  15. Plasma rich in growth factors

    The George Institute

    Low Reserve Ovarian

    phase 2 small molecule active

    1 trial
  16. Plerixafor

    The First People's Hospital of Lianyungang

    Relapsed Adult ALL

    phase 2 small molecule active

    1 trial
  17. Plerixafor

    Cardiff Oncology

    Acute Myeloid Leukaemia

    phase 2 small molecule completed

    1 trial
  18. Plerixafor

    SANGAMO THERAPEUTICS, INC

    Sickle Cell Disease

    phase 2 mab completed

    1 trial
  19. Pluvicto 1 000 MBq/mL solution for injection/infusion

    Ningbo Cancer Hospital

    Clear Cell Renal Cell Carcinoma (ccRCC)

    phase 2 small molecule active

    1 trial
  20. Pluvicto 1 000 MBq/mL solution for injection/infusion, Locametz 25 micrograms kit for radiopharmaceutical preparation

    Novartis Pharmaceuticals

    Progressive PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) with moderate and severe renal impairment and with normal renal function.

    phase 2 small molecule active

    1 trial
  21. Pociredir

    Fulcrum Therapeutics

    Sickle Cell Disease

    phase 2 small molecule active

    2 trials
  22. Polivy 30 mg powder for concentrate for solution for infusion., Epcoritamab (GEN3013), Truxima 100 mg concentrate for solution for infusion, IMBRUVICA 140 mg hard capsules, Golcadomide, Revlimid 10 mg hard capsules, IMBRUVICA 140 mg hard capsules, PIRTOBRUTINIB, Cyclophosphamide Injection 500 mg., Venetoclax, Venetoclax, Epcoritamab (GEN3013), Revlimid 25 mg hard capsules, Venetoclax, Decortin® H 20 mg Tabletten, Truxima 500 mg concentrate for solution for infusion, Decortin® H 5 mg Tabletten, Adriblastin®

    AbbVie Deutschland GmbH & Co. KG

    B-cell Non-Hodgkin's lymphoma, diffuse large B-cell lymphoma

    phase 2 small molecule active

    1 trial
  23. Polivy 30 mg powder for concentrate for solution for infusion., Mosunetuzumab, Mosunetuzumab, RoActemra 20 mg/mL concentrate for solution for infusion, Mosunetuzumab, Mosunetuzumab, Polivy 140 mg powder for concentrate for solution for infusion., Mosunetuzumab, Mosunetuzumab

    Hoffmann-La Roche

    Diffuse Large B-Cell Lymphoma (DLBCL)

    phase 2 small molecule active

    1 trial
  24. PolyCore

    Lacuna Pharma Pty Ltd

    End-Stage Kidney Disease

    phase 2 small molecule active

    1 trial
  25. Pomalidomide

    Celgene Europe Limited

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial
  26. Ponatinib

    Cardiff Oncology

    Acute Lymphoblastic Leukemia, Adult

    phase 2 small molecule active

    1 trial
  27. Ponatinib

    Takeda

    GIST

    phase 2 small molecule completed

    1 trial
  28. Ponatinib

    Takeda

    Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)

    phase 2 small molecule terminated

    1 trial
  29. Ponatinib

    Takeda

    Myeloid Leukemia, Chronic, Chronic Phase

    phase 2 small molecule completed

    1 trial
  30. Ponatinib

    Takeda

    Chronic Myeloid Leukemia

    phase 2 small molecule completed

    1 trial
  31. Ponsegromab (PF-06946860), Placebo for ponsegromab (pf-06946860) solution for injection

    Pfizer Australia Pty Ltd

    Heart failure

    phase 2 small molecule active

    1 trial
  32. Posaconazol STADA 100 mg magensaftresistente Tabletten, S65487 Solution for infusion 100 mg, Vidaza 25 mg/ml powder for suspension for injection

    The George Institute

    Acute Myeloid Leukemia (AML)

    phase 2 small molecule active

    1 trial
  33. Postoperative adjuvant lenvatinib

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial
  34. Povetacicept

    Vertex Pharmaceuticals (Australia) Pty.

    Myasthenia Gravis, Generalized

    phase 2 small molecule active

    1 trial
  35. Povorcitinib, Placebo, Povorcitinib, Povorcitinib

    Incyte

    Treatment of patients with inadequately controlled moderate to severe asthma

    phase 2 small molecule active

    1 trial
  36. Powder for concentrate for solution for infusion, Venclyxto 50 mg film-coated tablets, Zyloric 300 mg Tablets, Venclyxto 10 mg film-coated tablets, Venclyxto 50 mg film-coated tablets, Venclyxto 50 mg film-coated tablets, Fasturtec 1.5 mg/ml powder and solvent for concentrate for solution for infusion., Venclyxto 10 mg film-coated tablets, Venclyxto 10 mg film-coated tablets, Venclyxto 100 mg film-coated tablets, Venclyxto 50 mg film-coated tablets, Venclyxto 10 mg film-coated tablets, Zyloric 100 mg Tablet

    The George Institute

    "Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)/AML, or Chronic Myelomonocytic Leukemia (CMML)"

    phase 2 small molecule active

    1 trial
  37. Praliciguat

    Akebia Europe Limited

    Focal Segmental Glomerulosclerosis

    phase 2 small molecule active

    1 trial
  38. Pramlintide+Metreleptin

    Takeda

    Obesity

    phase 2 small molecule terminated

    1 trial
  39. Prazosin

    BRIGHT MINDS BIOSCIENCES INC.

    Continuous Methamphetamine Abuse

    phase 2 small molecule completed

    1 trial
  40. Pre-Quit Nicotine Lozenges

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 small molecule completed

    1 trial
  41. Pre-operative chemotherapy

    Nanjing Zenshine Pharmaceuticals

    Gastric Cancers

    phase 2 small molecule active

    1 trial
  42. Pre-operative chemotherapy

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  43. Precision Cells

    Ningbo Cancer Hospital

    Precision Cell Immunotherapy

    phase 2 mab active

    1 trial
  44. Pred Forte 10 mg/ml colirio en suspensión, Pred Forte 1% w/v, Eye Drops Suspension, Brimonidine Tartrate 0.2% w/v Eye Drops., Alphagan 2 mg/ml colirio en solución, IMGN151

    AbbVie Deutschland GmbH & Co. KG

    Recurrent endometrial cancer, recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer (EOC), recurrent cervical cancer

    phase 2 small molecule active

    1 trial
  45. Prednisolon 5 mg JENAPHARM, SPI-62_DF2, Capsule, hard for oral use as placebo for prednisolone., Film-coated tablet for oral use as placebo for Clofutriben (SPI-62)., SPI-62_DF1

    Lacuna Pharma Pty Ltd

    Polymyalgia rheumatica (PMR)

    phase 2 small molecule active

    1 trial
  46. Prednisone

    Nanjing Children's Hospital

    Henoch-Schoenlein Purpura Nephritis

    phase 2 small molecule active

    1 trial
  47. Prednisone

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Langerhans Cell Histiocytosis of Bone

    phase 2 small molecule active

    1 trial
  48. Prednisone + Jakavi(ruxolitinib)

    Yung NA

    GVHD - Graft-Versus-Host Disease

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs