Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs: 4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Bioequivalence of Mirabegron 50 mg Prolonged-Release Tablets in Healthy Participants Under Fasting Conditions.

Laboratorios Tillomed Spain S.L.U

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Mirabegron 50 mg Prolonged-Release Tablets in Healthy Participants Under Fed Conditions.

Laboratorios Tillomed Spain S.L.U

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Nilotinib 200 mg Capsules in Healthy Participants Under Fasting Conditions.

Lacuna Pharma Pty Ltd

No medical condition.

phase 1 other active

1 trial
Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fasting Conditions.

The George Institute

No medical condition.

phase 1 other active

1 trial
Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.

The George Institute

No medical condition.

phase 1 other active

1 trial
Bioequivalence of One Tablet of Gliclazide MR 90 mg (S005190) and One and a Half Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.

The George Institute

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Ruxolitinib 20 mg Tablets in Healthy Participants Under Fasting Conditions.

Lacuna Pharma Pty Ltd

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Ruxolitinib 25 mg Tablets in Healthy Participants Under Fasting Conditions

Lacuna Pharma Pty Ltd

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Testosterone Transdermal Gel in Healthy Female Participants.

Laboratorios Tillomed Spain S.L.U

No medical conditions.

phase 1 other active

1 trial
Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions.

Lacuna Pharma Pty Ltd

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets versus Xeljanz® 10 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions

Lacuna Pharma Pty Ltd

No medical condition

phase 1 other active

1 trial
Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets versus Xeljanz® 10 mg Film-Coated Tablets in Healthy Subjects Under Fed Conditions

Lacuna Pharma Pty Ltd

No medical condition.

phase 1 other active

1 trial
Bioequivalence of Vortioxetine 20 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions

Laboratorios Tillomed Spain S.L.U

No medical condition

phase 1 other active

1 trial
Bioequivalence of Vortioxetine 5 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.

Laboratorios Tillomed Spain S.L.U

No medical condition.

phase 1 other active

1 trial
Bioequivalence of two transdermal therapeutic systems delivering 100 mcg/h fentanyl

Alphapharm Pty Ltd

Bioequivalence trial in healthy volunteers

phase 1 other active

1 trial
Bioequivalence of two transdermal therapeutic systems delivering 100 mcg/h fentanyl

Alphapharm Pty Ltd

Bioequivalence trial in healthy volunteers

phase 1 other active

1 trial
Bioequivalence study 1 to compare pharmacokinetics of Parkinson´s disease drugs in healthy volunteers

Orion Laboratories Pty.

Parkinson disease

phase 1 other active

1 trial
Bioequivalence study 2 to compare pharmacokinetics of Parkinson´s disease drugs in healthy volunteers

Orion Laboratories Pty.

Parkinson desease

phase 1 other active

1 trial
Bioequivalence study comparing two temazepam 20 mg tablet formulations after fasted administration; an open, randomized, single centre, single dose study with crossover design in healthy subjects

Orion Laboratories Pty.

short-term treatment of insomnia

phase 1 other active

1 trial
Bioequivalence study of GP-IMP-001 with regards to reference product

Lacuna Pharma Pty Ltd

healthy volunteers

phase 1 other active

1 trial
Bioequivalence study of the oral suspension of netupitant/palonosetron combination product versus the hard capsules of netupitant/palonosetron combination product after a single dose administration to healthy male and female volunteers in an open-label, randomised, single centre, 2-treatment, 4-period, 2 sequence replicative design

Helsinn Birex Pharmaceuticals

Healthy volunteers

phase 1 other active

1 trial
Biological/Vaccine: therapeutic autologous dendritic cells.

LISATA THERAPEUTICS, INC.

Kidney Cancer

phase 1 mab terminated

1 trial
Biological: LV009 injection

The First People's Hospital of Lianyungang

CD19+ Relapse/Refractory B-ALL

phase 1 small molecule active

1 trial
Biological: PD-1

Hospital Authority, Hong Kong

Advanced Solid Tumor

phase 1 small molecule active

1 trial
Biological: ProHema-CB

Zafatek

Hematologic Malignancies

phase 1 mab terminated

1 trial
Biospecimen Collection

United Therapeutics Europe Ltd

Glioma

phase 1 other active

1 trial
Bortezomib

ONCOLYTICS BIOTECH INC

Recurrent Plasma Cell Myeloma

phase 1 small molecule completed

1 trial
Boserolimab

Merck KGaA, Darmstadt, Germany

Pharmacokinetics

phase 1 small molecule completed

1 trial
Brentuximab Vedotin

Takeda

Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic

phase 1 small molecule terminated

1 trial
Brigatinib

Takeda

Healthy Volunteers

phase 1 small molecule completed

1 trial
Briquilimab

Jasper Therapeutics

Allergic Asthma

phase 1 small molecule terminated

1 trial
Budesonide

Ferring Pharmaceuticals

Healthy

phase 1 small molecule completed

1 trial
Budesonide

Takeda

Healthy Volunteers

phase 1 small molecule completed

1 trial
Bumetanide

CATALYST PHARMACEUTICALS, INC.

Seizures

phase 1 small molecule completed

1 trial
Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination

Rhythm Pharmaceuticals Netherlands B.V.

Pain Management

phase 1 small molecule active

1 trial
Buprenorphine

Teva Pharma GmbH

Healthy

phase 1 small molecule completed

1 trial
Buprenorphine Injectable Solution - Part A

Indivior Pty Ltd

Healthy

phase 1 small molecule completed

1 trial
Buprenorphine/Naloxone + BEM/RZR

Atea Pharmaceuticals

Healthy Volunteer Study

phase 1 small molecule active

1 trial
Bupropion HCl

Teva Pharma GmbH

Depressive Disorder

phase 1 small molecule terminated

1 trial
Burosumab

Ultragenyx UK Limited

Cutaneous Skeletal Hypophosphatemia Syndrome (CSHS)

phase 1 small molecule active

1 trial
Busulfan Fresenius Kabi 6 mg/ml concentrate for solution for infusion, Neupogen 30 MU (0,6 mg/ml) solución inyectable en jeringa precargada filgrastim, Mozobil 20 mg/ml solution for injection, Merilen

Lacuna Pharma Pty Ltd

Inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells, Pyruvate Kinase Deficiency

phase 1 small molecule active

1 trial
C-4-29 Cells

Chongqing Precision Biotech Co., Ltd

Multiple Myeloma in Relapse

phase 1 mab active

1 trial
C-TIL051

Nektar Therapeutics UK Limited

Metastatic Non Small Cell Lung Cancer

phase 1 mab terminated

1 trial
C19-A3 GNP

Cardiff Oncology

Type 1 Diabetes

phase 1 small molecule completed

1 trial
C5951001- A Phase 1 Study of PF-08046876 in Participants with Advanced Solid Tumors.

Pfizer Australia Pty Ltd

advanced solid tumors

phase 1 other active

1 trial
C6001001 - A Study to Learn about the Study Medicine PF-08052667 in People with Bladder Cancer.

Pfizer Australia Pty Ltd

Non-muscle invasive bladder cancer (NMIBC)

phase 1 other active

1 trial
C6081001: A Phase 1 Study of PF-07985045 in Participants with Advanced Solid Tumors

Pfizer Australia Pty Ltd

KRAS mutated advanced solid tumors

phase 1 other active

1 trial
CABG + Mitral valve annuloplasty

United Therapeutics Europe Ltd

Mitral Regurgitation

phase 1 other completed

1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

Quick answer

Top sponsors

Bioequivalence of Mirabegron 50 mg Prolonged-Release Tablets in Healthy Participants Under Fasting Conditions.

Bioequivalence of Mirabegron 50 mg Prolonged-Release Tablets in Healthy Participants Under Fed Conditions.

Bioequivalence of Nilotinib 200 mg Capsules in Healthy Participants Under Fasting Conditions.

Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fasting Conditions.

Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.

Bioequivalence of One Tablet of Gliclazide MR 90 mg (S005190) and One and a Half Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.

Bioequivalence of Ruxolitinib 20 mg Tablets in Healthy Participants Under Fasting Conditions.

Bioequivalence of Ruxolitinib 25 mg Tablets in Healthy Participants Under Fasting Conditions

Bioequivalence of Testosterone Transdermal Gel in Healthy Female Participants.

Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions.

Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets versus Xeljanz® 10 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions

Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets versus Xeljanz® 10 mg Film-Coated Tablets in Healthy Subjects Under Fed Conditions

Bioequivalence of Vortioxetine 20 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions

Bioequivalence of Vortioxetine 5 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.

Bioequivalence of two transdermal therapeutic systems delivering 100 mcg/h fentanyl

Bioequivalence of two transdermal therapeutic systems delivering 100 mcg/h fentanyl

Bioequivalence study 1 to compare pharmacokinetics of Parkinson´s disease drugs in healthy volunteers

Bioequivalence study 2 to compare pharmacokinetics of Parkinson´s disease drugs in healthy volunteers

Bioequivalence study comparing two temazepam 20 mg tablet formulations after fasted administration; an open, randomized, single centre, single dose study with crossover design in healthy subjects

Bioequivalence study of GP-IMP-001 with regards to reference product

Biological/Vaccine: therapeutic autologous dendritic cells.

Biological: LV009 injection

Biological: PD-1

Biological: ProHema-CB

Biospecimen Collection

Bortezomib

Boserolimab

Brentuximab Vedotin

Brigatinib

Briquilimab

Budesonide

Budesonide

Bumetanide

Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination

Buprenorphine

Buprenorphine Injectable Solution - Part A

Buprenorphine/Naloxone + BEM/RZR

Bupropion HCl

Burosumab

Busulfan Fresenius Kabi 6 mg/ml concentrate for solution for infusion, Neupogen 30 MU (0,6 mg/ml) solución inyectable en jeringa precargada filgrastim, Mozobil 20 mg/ml solution for injection, Merilen

C-4-29 Cells

C-TIL051

C19-A3 GNP

C5951001- A Phase 1 Study of PF-08046876 in Participants with Advanced Solid Tumors.

C6001001 - A Study to Learn about the Study Medicine PF-08052667 in People with Bladder Cancer.

C6081001: A Phase 1 Study of PF-07985045 in Participants with Advanced Solid Tumors

CABG + Mitral valve annuloplasty

Frequently asked questions

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