Friday, July 10, 2026

Intelligence · Clinical pipeline

Autoimmune & immunology R&D Pipeline

Autoimmune, rheumatology, and immunology biologics in clinical development.

Programs 985

Quick answer

Autoimmune & immunology: NovaPharmaNews indexes 985 autoimmune & immunology clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. Autoimmune, rheumatology, and immunology biologics in clinical development.

Top sponsors

Pipeline programs

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  1. -, Rozanolixizumab

    Lacuna Pharma Pty Ltd

    Generalized Myasthenia Gravis

    phase 3 small molecule active

    1 trial
  2. -, Rozanolixizumab

    Lacuna Pharma Pty Ltd

    Generalized Myasthenia Gravis

    phase 3 small molecule active

    1 trial
  3. 01-13

    Apimeds Pharmaceuticals US

    Osteoarthritis of the Knee

    phase 3 mab completed

    1 trial
  4. 1305-0046

    Boehringer Ingelheim

    Systemic Autoimmune Rheumatic Diseases associated Interstitial Lung Diseases (SARD-ILD)

    phase 3 small molecule active

    1 trial
  5. 20-01/BetaSal-S

    Alphapharm Pty Ltd

    Chronic stable plaque psoriasis

    phase 3 other active

    1 trial
  6. 20190529

    Amgen

    Juvenile psoriatic arthritis

    phase 3 small molecule active

    1 trial
  7. 20190531

    Amgen

    Behçet’s disease is a chronic, relapsing, multisystem inflammatory disorder of unknown etiology characterized by 4 major symptoms (oral aphthous ulcers, genital ulcers, skin lesions, and ocular lesions) and occasionally by 5 minor symptoms (arthritis, gastrointestinal ulcers, epididymitis, vascular lesions, and central nervous system [CNS] symptoms) (Cho, 2012). Juvenile idiopathic arthritis is a heterogeneous group of chronic inflammatory disorders that initially presents in children by the age of 16 years. It refers to arthritis of at least 6 weeks duration of unknown etiology that begins in children less than 16 years old. Juvenile idiopathic arthritis has an annual incidence of 2 to 20 cases per 100 000 population and a prevalence of 16 to 150 cases per 100 000 population. It is an autoimmune disorder marked by abnormalities of immune responses (Adelowo, 2010).

    phase 3 small molecule active

    1 trial
  8. 230LE301

    Biogen

    Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus

    phase 3 small molecule active

    1 trial
  9. 230LE303

    Biogen

    systemic lupus erythematosus

    phase 3 small molecule active

    1 trial
  10. 230LE304

    Biogen

    systemic lupus erythematosus

    phase 3 small molecule active

    1 trial
  11. 230LE306

    Biogen

    Systemic lupus erythematosus

    phase 3 small molecule active

    1 trial
  12. 25 mg Ontamalimab

    Takeda

    Crohn's Disease

    phase 3 small molecule completed

    1 trial
  13. 410701BS

    Lacuna Pharma Pty Ltd

    Plaque psoriasis

    phase 3 small molecule active

    1 trial
  14. 608

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Axial Spondyloarthritis, Non-Radiographic

    phase 3 small molecule active

    1 trial
  15. 608 Q2W

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Plaque Psoriasis Patients

    phase 3 small molecule active

    1 trial
  16. 608 Q2W

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Psoriasis

    phase 3 small molecule completed

    1 trial
  17. 750 mg Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Generalized Pustular Psoriasis

    phase 3 small molecule completed

    1 trial
  18. 77242113CRD3001

    Janssen-Cilag International N.V.

    Moderately to Severely Active Crohn's Disease

    phase 3 small molecule active

    1 trial
  19. 77242113PSA3001

    Janssen-Cilag International N.V.

    Active Psoriatic Arthritis

    phase 3 small molecule active

    1 trial
  20. 77242113PSO3001

    Janssen-Cilag International N.V.

    Moderate to Severe Plaque Psoriasis

    phase 3 small molecule active

    1 trial
  21. 77242113PSO3002

    Janssen-Cilag International N.V.

    Moderate to Severe Plaque Psoriasis

    phase 3 small molecule active

    1 trial
  22. 77242113PSO3003

    Janssen-Cilag International N.V.

    Plaque Psoriasis

    phase 3 small molecule active

    1 trial
  23. 77242113PSO3004

    Janssen-Cilag International N.V.

    Moderate to Severe Plaque Psoriasis

    phase 3 small molecule active

    1 trial
  24. 77242113PSO3006

    Janssen-Cilag International N.V.

    Moderate to Severe Plaque Psoriasis

    phase 3 small molecule active

    1 trial
  25. 80202135SLE3001

    Janssen-Cilag International N.V.

    Systemic Lupus Erythematosus

    phase 3 small molecule active

    1 trial
  26. A3921145

    Pfizer Australia Pty Ltd

    Juvenile Idiopathic Arthritis (JIA)

    phase 3 small molecule active

    1 trial
  27. A3921210

    Pfizer Australia Pty Ltd

    Ulcerative Colitis (UC)

    phase 3 small molecule active

    1 trial
  28. AB-01-004

    Dr Reddy''s Laboratories (Australia) Pty Ltd

    Rheumatoid Arthritis

    phase 3 small molecule active

    1 trial
  29. AIN457 150 mg

    Novartis Pharmaceuticals

    Moderate to Severe Chronic Plaque-Type Psoriasis

    phase 3 small molecule completed

    1 trial
  30. ALXN1720 Placebo Product, Gefurulimab

    Alexion Europe SAS

    Generalized Myasthenia Gravis with autoantibodies against acetylcholine receptor (AChR)

    phase 3 small molecule active

    1 trial
  31. AMZ001 Diclofenac gel

    Amzell

    Osteoarthritis of Knee

    phase 3 small molecule completed

    1 trial
  32. APHP200038

    Pari Pharma GmbH

    lupus nephritis

    phase 3 small molecule active

    1 trial
  33. APHP230823

    Pari Pharma GmbH

    Adults aged at least 18 years with painful base-of-thumb osteoarthritis

    phase 3 small molecule active

    1 trial
  34. APHP240792

    Pari Pharma GmbH

    Septic arthritis

    phase 3 small molecule active

    1 trial
  35. APHP240804

    Pari Pharma GmbH

    Adult patients with symptomatic and inflammatory Hand osteoarthritis HOA.

    phase 3 small molecule active

    1 trial
  36. APHP240920

    Pari Pharma GmbH

    Cutaneous lupus erythematosus

    phase 3 small molecule active

    1 trial
  37. ARGX-113-2008

    argenx

    Generalized Myasthenia Gravis

    phase 3 small molecule active

    1 trial
  38. ARGX-113-2308

    argenx

    Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis

    phase 3 small molecule active

    1 trial
  39. ARGX-113-2315

    argenx

    Ocular Myasthenia Gravis

    phase 3 small molecule active

    1 trial
  40. ARQ-151 0.3% cream

    Arcutis Biotherapeutics

    Chronic Plaque Psoriasis

    phase 3 small molecule completed

    1 trial
  41. AXS-02

    Axsome Therapeutics

    Osteoarthritis, Knee

    phase 3 small molecule active

    1 trial
  42. Adalimumab

    AbbVie

    Juvenile Psoriatic Arthritis

    phase 3 small molecule active

    1 trial
  43. Adalimumab

    AbbVie

    Psoriatic Arthritis

    phase 3 small molecule completed

    1 trial
  44. Afimkibart

    Hoffmann-La Roche

    Moderately to Severely Active Crohns Disease

    phase 3 small molecule active

    1 trial
  45. Alicaforsen

    IONIS PHARMACEUTICALS INC

    Crohn's Disease

    phase 3 small molecule completed

    2 trials
  46. Amchafibrin

    Lxo Ireland Designated Activity Company

    Osteoarthritis, Knee

    phase 3 small molecule completed

    1 trial
  47. Amifampridine Phosphate

    CATALYST PHARMACEUTICALS, INC.

    Myasthenia Gravis, Generalized

    phase 3 small molecule completed

    1 trial
  48. Amifampridine Phosphate

    CATALYST PHARMACEUTICALS, INC.

    Myasthenia Gravis, MuSK

    phase 3 small molecule terminated

    1 trial

Frequently asked questions

How many autoimmune & immunology pipeline programs are tracked?

985 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.