Autoimmune & immunology · Phase I

Top sponsors

• Anaxis Pharma 19 programs
• Chinese Academy of 15 programs
• Takeda 8 programs
• Chongqing Precision Biotech 6 programs
• Nanjing Legend Biotech 6 programs
• Lakefront Biotherapeutics NV 5 programs
• MSD Merck Sharp 5 programs
• Regeneron UK 5 programs
• AstraZeneca 4 programs
• First People's Hospital 4 programs
• Sunshine Guojian Pharmaceutical 4 programs
• Century Therapeutics 3 programs

1. CNTY-101

   Century Therapeutics

   Systemic Lupus Erythematosus

   phase 1 · mab · active

   1 trial →

2. CNTY-101-151-01

   Century Therapeutics

   systemic lupus erythematosus [SLE]/lupus nephritis [LN], idiopathic inflammatory myopathy [IIM], and diffuse cutaneous systemic sclerosis [DcSSc]

   phase 1 · other · active

   1 trial →

3. CNTY-LTFU-01

   Century Therapeutics

   Hematological or solid tumor malignancies or autoimmune diseases

   phase 1 · other · active

   1 trial →

4. CPIT565B12101

   Novartis Pharmaceuticals

   Systemic Lupus Erythematosus

   phase 1 · other · active

   1 trial →

5. CPIT565C12101

   Novartis Pharmaceuticals

   Rheumatoid Arthritis

   phase 1 · other · active

   1 trial →

6. CTX112

   S.A.

   SLE (Systemic Lupus)

   phase 1 · mab · active

   1 trial →

7. D740AC00001

   AstraZeneca AB

   Systemic Lupus Erythematosus, Rheumatoid Arthritis

   phase 1 · other · active

   1 trial →

8. D9640C00001

   AstraZeneca AB

   Rheumatoid Arthritis

   phase 1 · other · active

   1 trial →

9. D9690C00007

   AstraZeneca AB

   Crohn's disease

   phase 1 · other · active

   1 trial →

10. D9961C00001

    AstraZeneca AB

    Systemic Lupus Erythematosus, Rheumatoid Arthritis, Idiopathic Inflammatory Myopathies

    phase 1 · other · active

    1 trial →

11. DEUCR-07-25

    Lacuna Pharma Pty Ltd

    plaque psoriasis

    phase 1 · other · active

    1 trial →

12. DEUCR-08-25

    Lacuna Pharma Pty Ltd

    plaque psoriasis

    phase 1 · other · active

    1 trial →

13. Delayed Release 6 mercaptopurine

    Teva Pharma GmbH

    Crohns Disease

    phase 1 · small molecule · completed

    1 trial →

14. EP-104IAR

    EUPRAXIA PHARMACEUTICALS INC.

    Osteoarthritis, Knee

    phase 1 · small molecule · completed

    1 trial →

15. Effect of Renal Impairment on Enpatoran Pharmacokinetics

    Merck Sharp and Dohme

    Healthy volunteers and patients with renal impairment; Intended indication: autoimmune diseases; systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE), as well as dermatomyositis (DM) and polymyositis (PM).

    phase 1 · other · active

    1 trial →

16. Etrasimod Arginine Blue

    Pfizer Australia Pty Ltd

    Ulcerative Colitis and immune-mediated inflammatory disorders

    phase 1 · small molecule · active

    1 trial →

17. FT819 in B-cell Mediated Autoimmune Diseases

    Zafatek

    B-cell Mediated Autoimmune Diseases

    phase 1 · other · active

    1 trial →

18. FX201

    Pacira Ireland Limited

    Osteoarthritis, Knee

    phase 1 · mab · active

    1 trial →

19. Fasinumab AI

    Regeneron UK Limited

    Osteoarthritis, Knee

    phase 1 · small molecule · completed

    1 trial →

20. GA43191

    Hoffmann-La Roche

    Systemic Lupus Erythematosus (SLE)

    phase 1 · other · active

    1 trial →

21. GA46438

    Hoffmann-La Roche

    Active Ulcerative Colitis (UC)

    phase 1 · other · active

    1 trial →

22. GBP-NIB1-101

    Lacuna Pharma Pty Ltd

    rheumatoid arthritis

    phase 1 · other · active

    1 trial →

23. GLPG-0634-CL-131

    Alfasigma S.p.A.

    juvenile idiopathic arthritis

    phase 1 · small molecule · active

    1 trial →

24. GLPG1972 600 mg oral solution fasted

    Lakefront Biotherapeutics NV

    Osteoarthritis

    phase 1 · small molecule · completed

    1 trial →

25. GLPG1972 cohort 1

    Lakefront Biotherapeutics NV

    Osteoarthritis

    phase 1 · small molecule · completed

    1 trial →

26. GLPG3667

    Lakefront Biotherapeutics NV

    Plaque Psoriasis

    phase 1 · small molecule · completed

    1 trial →

27. GLPG3970 film-coated tablet

    Lakefront Biotherapeutics NV

    Systemic Lupus Erythematosus

    phase 1 · small molecule · terminated

    1 trial →

28. GRT-1C101

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 · other · active

    1 trial →

29. GRT-1C102

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 · other · active

    1 trial →

30. GS-0272

    Gilead Sciences Ireland UC

    Rheumatoid Arthritis

    phase 1 · small molecule · active

    1 trial →

31. HN2301 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Systemic Lupus Erythematosus

    phase 1 · small molecule · active

    1 trial →

32. HN2302 Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Disease

    phase 1 · small molecule · active

    1 trial →

33. Human Umbilical Mesenchymal Stem Cells

    The First People's Hospital of Lianyungang

    Osteoarthritis, Knee

    phase 1 · mab · active

    1 trial →

34. Humanized TNFα monoclonal antibody

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Rheumatoid Arthritis

    phase 1 · small molecule · completed

    1 trial →

35. IASO206 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 · mab · active

    1 trial →

36. IM034-1000

    Bristol-Myers Squibb Australia Pty Ltd

    Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus, Systemic Lupus Erythematosus

    phase 1 · other · active

    1 trial →

37. IM060-0001

    Bristol-Myers Squibb Australia Pty Ltd

    Systemic Sclerosis, Idiopathic Inflammatory Myopathy, Rheumatoid Arthritis, Systemic Lupus Erythematosus

    phase 1 · other · active

    1 trial →

38. Ixazomib

    Takeda

    Lupus Nephritis

    phase 1 · small molecule · terminated

    1 trial →

39. JADE201

    Jade Biosciences

    Rhematoid Arthritis

    phase 1 · small molecule · active

    1 trial →

40. JANX011

    Janux Therapeutics

    Autoimmune

    phase 1 · small molecule · active

    1 trial →

41. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 · mab · active

    1 trial →

42. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 · mab · terminated

    1 trial →

43. LD and GC012F CAR-T Cell Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rheumatoid Arthritis

    phase 1 · small molecule · active

    1 trial →

44. LUCAR-DKS1 NK cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 · mab · active

    1 trial →

45. LUCAR-G79 T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 · mab · active

    1 trial →

46. LUCAR-G79D T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 · mab · active

    1 trial →

47. LVIVO-TaVec400 product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)

    phase 1 · mab · active

    1 trial →

48. LX3305

    LEXICON PHARMACEUTICALS, INC.

    Rheumatoid Arthritis

    phase 1 · small molecule · completed

    1 trial →

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