Wednesday, July 8, 2026

Patent intelligence · US

US 10988538

Bispecific signaling agents and uses thereof

granted A61KA61K2039/505A61K2039/57A61K38/00
Status granted
Linked drugs 2
Pipeline programs 6
Years to expiry 15
Applicant portfolio 222
Patent details — US 10988538
Jurisdiction
US
Status
granted
Grant date
Apr 27, 2021
Expiration
Apr 22, 2041
Claims
45
CPC classes
A61K, A61K2039/505, A61K2039/57, A61K38/00
View on Google Patents ↗

Quick answer

US 10988538 (Bispecific signaling agents and uses thereof) is held by Orionis Biosciences, Inc. Status: granted. Granted Apr 27, 2021. Expires Apr 22, 2041 (15 years remaining) — relevant for patent-cliff and LOE planning.

Key facts

Grant date
Expiration
Claims
45
CPC classes
A61K, A61K2039/505, A61K2039/57, A61K38/00, A61K39/395, A61P

More from Orionis Biosciences, Inc

Related pharmaceutical patents in our USPTO index.

  1. US 12409188

    Modulators of HSD17B13 expression

    Ionis Pharmaceuticals, Inc. · Expires Sep 4, 2045

    granted
  2. US 12410225

    Modulation of dendritic cell lineages

    Orionis Biosciences, Inc · Expires Sep 4, 2045

    granted
  3. US 12410430

    Modulating apolipoprotein (A) expression

    Ionis Pharmaceuticals, Inc. · Expires Sep 4, 2045

    granted
  4. US 12364753

    CD8 binding agents

    Orionis Biosciences, Inc · Expires Jul 17, 2045

    granted
  5. US 12351633

    PD-1 and PD-L1 binding agents

    Orionis Biosciences, Inc · Expires Jul 3, 2045

    granted
  6. US 12350285

    Compounds and methods for reducing ATXN3 expression

    Ionis Pharmaceuticals, Inc. · Expires Jul 3, 2045

    granted
  7. US 12351614

    CLEC9A-based chimeric protein complexes

    Orionis Biosciences, Inc · Expires Jul 3, 2045

    granted
  8. US 12343357

    Compositions and methods for modulating MECP2 expression

    Ionis Pharmaceuticals, Inc. · Expires Jun 26, 2045

    granted

Frequently asked questions

What is US patent 10988538?

US 10988538 (Bispecific signaling agents and uses thereof) is held by Orionis Biosciences, Inc. Status: granted. Granted Apr 27, 2021. Expires Apr 22, 2041 (15 years remaining) — relevant for patent-cliff and LOE planning.

Who owns US 10988538?

Orionis Biosciences, Inc is listed as the applicant in USPTO PatentsView records indexed by NovaPharmaNews. We track 222 pharmaceutical patents for this assignee.

When does US 10988538 expire?

Our index shows an expiration date of Apr 22, 2041 (15 years from today). Confirm material dates against USPTO, FDA Orange Book, or qualified counsel before contractual decisions.