Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10213389

    Controlled release compositions comprising a combination of isosorbide dinitrate and hydralazine hydrochloride

    RECRO GAINESVILLE LLC · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10213395

    Toxic aldehyde related diseases and treatment

    Aldeyra Therapeutics, Inc. · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10212923

    Humanized dipeptidyl-peptidase IV (DPP4) animals

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10213397

    Microtubule polymerization modulators for treating LMNA-related dilated cardiomyopathy

    Northwestern University · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10213488

    Delivery of therapeutic agents by a collagen binding protein

    Montefiore Medical Center · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10214498

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10213445

    Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10213508

    Etanercept formulations stabilized with xylitol

    Coherus BioSciences, Inc. · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10213380

    Method of treating ear pain

    Try This First, Inc. · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10214508

    Nitrogen-containing heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10214509

    Amino-substituted heterocyclic derivatives as sodium channel inhibitors

    Almirall, S.A. · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10214553

    Solid state forms of sofosbuvir

    TEVA PHARMACEUTICALS INTERNATIONAL GMBH · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10214529

    Small molecules for the treatment of primary cancer and cancer metastasis

    The Board of Regents of the University of Texas System · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10214732

    Lysin agent and method of use for diagnostic testing

    The United States of America, as represented by the Secretary of Homeland Security · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10214581

    Compositions and methods for treating and preventing Staphylococcus aureus infections

    XBIOTECH INC. · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10215825

    Magnetic microstructures for magnetic resonance imaging

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10213456

    Alginate oligosaccharides and the derivatives thereof as well as the manufacture and the use of the same

    OCEAN UNIVERSITY OF CHINA · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10214785

    Adeno-associated virus virions with variant capsid and methods of use thereof

    The Regents of the University of California · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10214531

    Substituted amino triazoles, and methods using same

    Institute for Drug Discovery, LLC · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10213400

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. CA 3072003

    PROCEDE DE FILTRATION VIRALE DU FACTEUR DE VON WILLEBRAND

    CSL BEHRING GMBH [DE] · Granted Thu Feb 28 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 23 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10220028

    Thio compounds

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10221164

    Cannabinergic nitrate esters and related analogs

    Northwestern University · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10220103

    Magnetic microstructures for magnetic resonance imaging

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10221174

    N-(phenylsulfonyl)benzamides and related compounds as BCL-2 inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10220022

    Compositions and methods employing Wolbachia FtsZ as a target for Albendazole sulfone

    The Regents of the University of California · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10220093

    Long-acting semi-solid lipid formulations

    MIRA PHARMA CORPORATION · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10221161

    Inhibitors of plasma kallikrein

    KalVista Pharmaceuticals Limited · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10220117

    Methods of mammalian retinal stem cell production and applications

    The Regents of the University of California · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10221195

    Pyridine compounds

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10221222

    Dermaseptin-type and piscidin-type antimicrobial peptides

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10220002

    Controlled-release peptide compositions and uses thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10220004

    Method of controlled delivery using sub-micron-scale machines

    The Regents of the University of California · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10220020

    Polymer-des-ethyl sunitinib conjugates

    Nektar Therapeutics · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10221223

    Methods and compositions for treating neurodegenerative disorders and alzheimer's disease and improving normal memory

    The Regents of the University of California · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10220070

    Alphaa-crystallin mimetic peptides and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10220082

    WT1 vaccine

    Inovio Pharmaceuticals, Inc. · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10221244

    Anti-CSF1R antibody and anti PD-1 antibody combination therapy for cancer

    Five Prime Therapeutics, Inc. · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10221226

    LEDGF peptides and formulations thereof for treatment of degenerative disorders

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10220042

    Modified release preparations containing oxcarbazepine and derivatives thereof

    Supernus Pharmaceuticals, Inc. · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10221408

    Compositions of prokaryotic phenylalanine ammonia-lyase variants and methods of using compositions thereof

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10221235

    Endotrophin neutralization and use thereof

    The Board of Regents of the University of Texas System · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10220001

    Active self-healing biomaterial system

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10220029

    Pharmaceutical composition comprising glutarimide derivatives and use thereof in the treatment of eosinophilic diseases

    OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU “PHARMENTERPRISES” · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10219492

    Compounds and methods for altering RSV replication rate

    The Board of Regents of the University of Texas System · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10220046

    Compositions and methods for disease treatment using nanoparticle delivered compounds

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10220078

    Methods of using thrombin derivatives to treat medulloblastoma

    The Board of Regents of the University of Texas System · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10221414

    Compositions for modulating C9ORF72 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Mar 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.