Wednesday, July 8, 2026

Drug profile · INN

bevacizumab

bevacizumab (ABEVMY) is a vascular endothelial growth factor a inhibitor. Associated with Amgen. Route of administration: intravenous. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01FG01
US status approved
Patents linked 20
Pipeline programs 132
News articles 5
Drug details — bevacizumab

Quick answer

bevacizumab (ABEVMY) is a vascular endothelial growth factor a inhibitor. Associated with Amgen. Route of administration: intravenous. Current US regulatory status: approved.

Key facts

INN bevacizumab
Brand ABEVMY
Mechanism Vascular endothelial growth factor A inhibitor
Target Vascular endothelial growth factor A, long form
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INTRAVENOUS
Formulation VIAL
ATC code L01FG01
Originator Amgen

Mechanism of action

Vascular endothelial growth factor A inhibitor

Primary target: Vascular endothelial growth factor A, long form

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved
NMPA clinical trials

Recent coverage

Pharma bets on PD-1/VEGF bispecifics: Is lung cancer the wrong target?
High impact Analysisnon-small cell lung cancerJun 6, 2026

Pharma bets on PD-1/VEGF bispecifics: Is lung cancer the wrong target?

FDA · non-small cell lung cancer · 5 min

While many drugmakers are focused on lung cancer for PD-1/VEGF bispecifics, emerging evidence shows the liver may offer higher value. This analysis covers the mechanism, key players, and strategic implications for pharma teams.

Dr. Sarah Mitchell
Outlook Therapeutics Resubmits LYTENAVA BLA to FDA, Initiating 60-Day Review
High impact NewsJun 3, 2026

Outlook Therapeutics Resubmits LYTENAVA BLA to FDA, Initiating 60-Day Review

FDA · 5 min

Outlook Therapeutics has resubmitted its Biologics License Application (BLA) for LYTENAVA (bevacizumab-vikg) to the FDA, initiating a 60-day Class 1 review. This marks a critical step for the drug's potential approval in treating neovascular age-related macular degeneration (nAMD).

Dr. Sarah Mitchell
This Week’s Biopharma News: New Approvals, Appeals, and AI
High impact AnalysisJun 2, 2026

This Week’s Biopharma News: New Approvals, Appeals, and AI

FDA · 10 min

This week's biopharma news highlights significant FDA approvals for Datroway and Hepcludex, a key appeal win for Outlook regarding bevacizumab, and promising Phase 3 data for BioMarin's VOXZOGO. The evolving landscape also sees increased integration of AI in drug development and regulatory processes.

Dr. Sarah Mitchell
Biosimilar Market Growth India: Key Drivers, Challenges & Opportunities
Standard impact NewsautoimmuneApr 4, 2026

Biosimilar Market Growth India: Key Drivers, Challenges & Opportunities

CDSCO · autoimmune · 10 min

The biosimilar market in India is poised for significant growth, driven by increasing demand for affordable biologics like Trastuzumab, alongside various challenges and opportunities.

Dr. Yuki Tanaka

Pipeline programs

  1. 20210081 Phase 3 · Amgen · Colorectal Cancer (CRC)
  2. 61186372COR3002 Phase 3 · Janssen-Cilag International N.V · KRAS/NRAS and BRAF Wildtype Recurrent, Unresectable or Metas
  3. ABC-HCC Phase 3 · George Institute for · intermediate-stage hepatocellular carcinoma
  4. BEATcc Phase 3 · Ningbo Cancer Hospital · Metastatic (stage IVB), Persistent, or Recurrent Carcinoma o
  5. BEVACIZUMAB, ERLOTINIB Phase 3 · Telethon Foundation · Non-squamous Non-small Cell Lung Cancer
  6. BOOG 2010-02 Stop&Go study Phase 3 · Teva Pharma · Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
  7. BRADI ICO-2023-15 Phase 3 · CERo Therapeutics · Brain metastases of cancer > brain radionecrosis
  8. BX44273 Phase 3 · HOFFMANN-LA ROCHE · This is an extension study designed to provide continued tre

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
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Frequently asked questions

What is bevacizumab?

bevacizumab (ABEVMY) is a vascular endothelial growth factor a inhibitor. Associated with Amgen. Route of administration: intravenous. Current US regulatory status: approved.

What is the brand name for bevacizumab?

ABEVMY is a marketed brand name for bevacizumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of bevacizumab?

bevacizumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.