Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10174077

    Method of inhibiting activity of cell surface fibroblast activation protein alpha

    The Board of Regents of the University of Oklahoma · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10172930

    Virus like particle purification

    Takeda Vaccines, Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10172888

    Enhanced stem cell composition

    Fate Therapeutics, Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10172911

    Methods of modulating erythropoiesis with arginine vasopressin receptor 1B molecules

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10174318

    Antisense oligonucleotide compositions

    Ionis Pharmaceuticals, Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10174098

    Anti-human papillomavirus 16 E7 T cell receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10174290

    Method to increase the infectivity of virus particles

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10174302

    Modified L-asparaginase

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10174085

    Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof

    INTEGRATED BIOTHERAPEUTICS, INC. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10172880

    Talen-based gene correction

    Regents of the University of Minnesota · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10174041

    Methods and compositions for inhibiting the interaction of menin with MLL proteins

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10172840

    Bach1 inhibitors in combination with Nrf2 activators and pharmaceutical compositions thereof

    VTV THERAPEUTICS LLC · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10172841

    Inhibition of crystal growth of roflumilast

    Arcutis, Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10173980

    Mixed disulfide conjugates of thienopyridine compounds and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10172976

    Muscle cell patches and uses therefor

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10174018

    Protein kinase inhibitors

    Princeton Drug Discovery, Inc · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10172827

    Pro-neurogenic compounds

    The Board of Regents of the University of Texas System · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10173985

    Aminoindazole derivatives as sodium channel inhibitors

    Almirall, S.A. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10172849

    Compositions comprising buprenorphine

    Indivior UK Limited · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10174099

    Cell

    AUTOLUS LIMITED · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10175170

    Metal coating of rare earth nano-phosphors and uses thereof

    The Regents of the University of California · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10172908

    Method for treating cognitive dysfunction

    ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10172933

    Mosaic vaccines for serotype a foot-and-mouth disease virus

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10172932

    Ebola virus disease vaccine taking human replication deficient adenovirus as vector

    Institute of Biotechnology, Academy of Military Medical Sciences, China · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10172836

    Methods for dosing an orally active 1,2,4-oxadiazole for nonsense mutation supression therapy

    PTC THERAPEUTICS, INC. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10172695

    Method for manufacturing dental mill blank

    KURARAY NORITAKE DENTAL INC. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10172937

    Method of treatment of malignant solid tumors with afucosylated anti-FGFR2IIIb antibodies

    Five Prime Therapeutics, Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10172789

    Compositions for transdermal delivery of mTOR inhibitors

    PALVELLA THERAPEUTICS, INC. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10172834

    (2R,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid

    Theravance Biopharma R&D IP, LLC · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10172831

    Catalytic scavengers of organophosphates to potentiate butyrylcholinesterase (hBChE) as a catalytic bioscavenger and methods for making and using them

    The Regents of the University of California · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10173074

    Cancer stem cell vaccination and treatment

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10172844

    Use of CDK9 inhibitors to reduce cartilage degradation

    The Regents of the University of California · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10173998

    Antifungal compound process

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10174039

    P2X3 and/or P2X2/3 compounds and methods

    Asana BioSciences, LLC · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10172920

    Sleep apnea treatment

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10172864

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10172951

    Dendrimer based nanodevices for therapeutic and imaging purposes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10172938

    Multimode degradable hydrogels for controlled release of cargo substances

    The Regents of the University of California · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10173989

    1,2,4-oxadiazole derivatives as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10172786

    Oral care composition comprising cannabinoids

    AXIM BIOTECHNOLOGIES. INC. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10173987

    Hydrazide containing nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 03 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 2019008774

    PHARMACEUTICAL FORMULATIONS COMPRISING NITROCATECHOL DERIVATIVES AND METHODS OF MAKING THE SAME

    BIAL PORTELA & Cª S A [PT] · Granted Thu Jan 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10179173

    Semi-solid delivery systems

    Regents of the University of Minnesota · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10179792

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10179783

    Tetrahydropyridopyrazines as modulators of GPR6

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10179112

    Viral vector nanocapsule for targeting gene therapy and its preparation

    The Regents of the University of California · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10179819

    Anti-PSMA antibodies, bispecific antigen-binding molecules that bind PSMA and CD3, and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10179119

    Method of treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.