Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10130681

    Use of a VEGF antagonist to treat angiogenic eye disorders

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10130711

    Chemical structures for localized delivery of therapeutic agents

    The Regents of the University of California · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10130080

    Obesity animal model and methods for making and using thereof

    PERFECT (CHINA) CO., LTD. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10130593

    Methods of regulating cannabinoid receptor activity-related disorders and diseases

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10130696

    Method of conferring a protective immune response to norovirus

    Takeda Vaccines, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10130560

    Bioactive “smart” dental composite materials

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10130600

    Lipid scavenging in Ras cancers

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10130720

    Composition comprising a polymeric reagent

    Nektar Therapeutics · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10130604

    Composition and method for treating neurodegenerative disease

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10138483

    Transferrin/transferrin receptor-mediated siRNA delivery

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10138298

    Anti-IL-2 antibodies and compositions and uses thereof

    The Regents of the University of California · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10138271

    Native and agonist CTL epitopes of the MUC1 tumor antigen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10137299

    Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects

    The Regents of the University of California · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10137184

    Scaffolds for cell transplantation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10137133

    Methods for treatment of diseases

    Galera Labs, LLC · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10137104

    Combination therapy with an anti-hyaluronan agent and therapeutic agent

    HALOZYME, INC. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10137100

    Administration of serine protease inhibitors to the stomach

    The Regents of the University of California · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10137212

    Tetrahydroxamate chelators of zirconium89 and niobium90 for use in diagnostic applications

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10138466

    Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells

    REGENERATIVE MEDICAL SOLUTIONS, INC. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10137131

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10137136

    Methods for inhibiting muscle atrophy

    THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10137121

    Methods of treating cancer with farnesyltransferase inhibitors

    Kura Oncology, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10137130

    Methods of treatment of malignancies

    Agios Pharmaceuticals, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10137188

    Cell lines for virus production and methods of use

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10137186

    Compositions and methods for live, attenuated alphavirus formulations

    Takeda Vaccines, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10137190

    Nucleic acid molecules encoding ferritin-hemagglutinin fusion proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10137193

    Methods for treating or preventing asthma by administering an IL-4R antagonist

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10138220

    Diamide compounds having muscarinic receptor antagonis and beta2 adrenergic receptor agonist activity

    Theravance Respiratory Company, LLC · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10138214

    Substituted triazoles and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10138219

    Methods and compounds for restoring mutant p53 function

    PMV PHARMACEUTICALS, INC. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10138228

    Isoxazole derivatives as FXR agonists and methods of use therof

    Enanta Pharmaceuticals, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10138482

    Compositions for modulating C9ORF72 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10138255

    Piperazine derivatives as HIV protease inhibitors

    MSD R&D (China) Co. Ltd. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10138277

    Virus-like particles and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10138272

    Matriptase and u-plasminogen activator substrates and other cleavable moieties and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10138291

    Factor VIII complex with XTEN and von Willebrand Factor protein, and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10138279

    Compositions and methods for Bacillus anthracis vaccination

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10138486

    Inhibitors of DEK protein and related methods

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10143709

    Use of ASC and ASC-CM to treat ARDS, SARS, and MERS

    The United States of America Department of Veteran Affairs As Represented By The Technology Transfer Program · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10143721

    Combination product for the prevention of sexually transmitted infections

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10143724

    Anti-SSX-2 T cell receptors and related materials and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10143748

    B-cell reduction using CD37-specific and CD20-specific binding molecules

    Aptevo Research and Development LLC · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10143760

    Liver-specific constructs, factor VIII expression cassettes and methods of use thereof

    Sangamo Therapeutics, Inc. · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10144729

    Isoxazole analogs as FXR agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10144726

    Modulators of the p70S6 kinase for use in the treatment of brain disorders and triple-negative breast cancer

    SENTINEL ONCOLOGY LIMITED · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10144804

    Method for preparing functionalized polymers from polymer alcohols

    Nektar Therapeutics · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10144762

    Antibacterial antisense oligonucleotide and method

    Sarepta Therapeutics, Inc. · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10144767

    Anti-microbial peptides and coatings

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Dec 04 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.