Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2036

Annual patent cliff calendar for 2036 — US pharmaceutical patents by expiration date.

Patents
1,428

Quick answer

1,428 indexed pharmaceutical patents have expiration dates in 2036. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9399666

    Inhibiting interaction between the HIF-1ALPHA and p300/CBP with hydrogen bond surrogate-based helices

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9399627

    Substituted macrocyclic compounds having proteasome inhibitory activity

    The Regents of the University of California · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9399674

    Human antibodies to Clostridium difficile toxins

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9399649

    Compounds for treating spinal muscular atrophy

    PTC THERAPEUTICS, INC. · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9399639

    Substituted azaindole compounds, salts, pharmaceutical compositions thereof and methods of use

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9399775

    RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9399774

    Modulation of transthyretin expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9399662

    Concurrent chemotherapy and immunotherapy

    The Board of Regents of the University of Texas System · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9399672

    Hepatitis C virus neutralizing antibody

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 2016213609

    OPHTHALMIC SUSPENSION COMPOSITION

    BAUSCH & LOMB [US] · Granted Thu Jul 28 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 23 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9403815

    Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms

    The Regents of the University of California · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9403839

    Pyran-spirocyclic piperidine amides as modulators of ion channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9403832

    Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use

    LEXICON PHARMACEUTICALS, INC. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9403885

    Wnt compositions and therapeutic uses of such compositions

    Fate Therapeutics, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9403872

    Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts of cell-surface metalloproteinases or plasminogen activator receptors

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9403856

    Bcl-2/Bcl-xL inhibitors and therapeutic methods using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9403908

    Method for altering hematopoietic progenitor cell adhesion, differentiation, and migration

    The Regents of the University of California · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9404081

    Pyruvate kinase activators for use in therapy

    Agios Pharmaceuticals, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9403911

    Compositions and methods for detection and treatment of cancer

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9403819

    Apoptosis signal-regulating kinase 1 inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9402935

    Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs

    Lutonix, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9402898

    Stabilized formulations containing anti-Ang2 antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9402881

    Tissue regeneration and wound treatment methods with platelet derived compositions

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9402841

    Pyridinyl and fused pyridinyl triazolone derivatives

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9402820

    Use of pyruvate or succinate to enhance the efficacy of a hypoxia activated prodrug for the treatment of tumors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9403755

    Isometheptene isomer

    TONIX PHARMA HOLDINGS LIMITED (BERMUDA) · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9403792

    Methods of using pyruvate kinase activators

    Agios Pharmaceuticals, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9403801

    Substituted heteroaryl compounds and methods of use

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9404114

    Antisense modulation of GCGR expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9404113

    Antisense modulation of PTP1B expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9404088

    Chitosan-based non-viral methods for transfecting gut cells in vivo

    ENGENE, INC. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9402806

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9402807

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9402830

    Methods of treating dyskinesia and related disorders

    Melior Discovery, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9402840

    Crystalline form of a quinolinone-carboxamide compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9402876

    Method and pharmaceutical composition for hair growth

    The Regents of the University of California · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9402850

    BAX agonist, compositions, and methods related thereto

    The Board of Regents of the University of Texas System · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9402879

    Methods and compositions for modulating PD1

    Sangamo Biosciences, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9402889

    Live, oral vaccine for protection against Shigella dysenteriae serotype 1

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9402911

    Multifunctional small molecules

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9403778

    Agents that prevent or repair skin damage

    Regents of the University of Minnesota · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9403783

    Methods for producing viloxazine salts and novel polymorphs thereof

    Supernus Pharmaceuticals, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9403002

    Swallowable capsule and method for stimulating incretin production within the intestinal tract

    Rani Therapeutics, LLC · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9403811

    Crystalline forms of azilsartan medoxomil potassium and preparation and uses thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9403814

    Crystalline forms of dihydropyrimidine derivatives

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9403800

    Compounds for inhibition of cancer cell proliferation

    ChemRegen, Inc. · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9403802

    Heterocyclic compound and use therefor

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 28 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9410969

    Method for determining and treating amyotrophic lateral sclerosis

    China Medical University · Granted Tue Aug 09 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 04 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2036?

1,428 published patents in our USPTO index have expiration dates falling in calendar year 2036.