Wednesday, July 8, 2026

Drug profile · INN

dofetilide

dofetilide (TIKOSYN) is a herg blocker. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: withdrawn Cardiovascular system (C01) C01BD04
US status approved
Patents linked 1
Pipeline programs 1
News articles 0
Drug details — dofetilide
US status
approved
Class
Cardiovascular system (C01)
Route
ORAL
Patents
1
Programs
1
Data quality
0.89

Quick answer

dofetilide (TIKOSYN) is a herg blocker. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN dofetilide
Brand TIKOSYN
Mechanism HERG blocker
Target Voltage-gated inwardly rectifying potassium channel KCNH2
Therapeutic class Cardiovascular system (C01)
Route ORAL
Formulation CAPSULE
ATC code C01BD04

Mechanism of action

HERG blocker

Primary target: Voltage-gated inwardly rectifying potassium channel KCNH2

Approval history

Authority Status Date
FDA approved
EMA withdrawn

Pipeline programs

  1. Dofetilide Phase 1 · BRIGHT MINDS BIOSCIENCES · Drug-induced QT Prolongation

Related & competitor drugs

  1. alirocumab Cardiovascular system (C10)
  2. aliskiren Cardiovascular system (C09)
  3. amiodarone hydrochloride HERG blocker
  4. azilsartan medoxomil Cardiovascular system (C09)
  5. bempedoic acid Cardiovascular system (C10)
  6. bosentan Cardiovascular system (C02)
  1. US 9597302

    Combination of dofetilide and mexiletine for the prevention and treatment of atrial fibrillation

    Expires Mon Mar 16 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is dofetilide?

dofetilide (TIKOSYN) is a herg blocker. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for dofetilide?

TIKOSYN is a marketed brand name for dofetilide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of dofetilide?

dofetilide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.