Wednesday, July 8, 2026

Drug profile · INN

tradipitant

tradipitant (NEREUS) is a neurokinin 1 receptor antagonist. Associated with Vanda Pharmaceuticals Netherlands B.V.. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 6
Pipeline programs 10
News articles 1
Drug details — tradipitant

Quick answer

tradipitant (NEREUS) is a neurokinin 1 receptor antagonist. Associated with Vanda Pharmaceuticals Netherlands B.V.. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN tradipitant
Brand NEREUS
Mechanism Neurokinin 1 receptor antagonist
Target Substance-P receptor
Route ORAL
Formulation CAPSULE

Mechanism of action

Neurokinin 1 receptor antagonist

Primary target: Substance-P receptor

Approval history

Authority Status Date
FDA approved

Recent coverage

Pipeline programs

  1. Tradipitant Phase 3 · Anaxis Pharma · Idiopathic or diabetic gastroparesis with moderate to severe
  2. Tradipitant Phase 3 · Vanda Pharmaceuticals Netherlands · Atopic Dermatitis
  3. Tradipitant Phase 3 · Vanda Pharmaceuticals Netherlands · Coronavirus Infection
  4. Tradipitant Phase 3 · Vanda Pharmaceuticals Netherlands · Motion Sickness
  5. Tradipitant Phase 3 · Vanda Pharmaceuticals Netherlands · Nausea and Vomiting
  6. Tradipitant Phase 3 · Vanda Pharmaceuticals Netherlands · Idiopathic Gastroparesis
  7. Tradipitant Phase 2 · Vanda Pharmaceuticals Netherlands · Healthy Volunteer
  8. Tradipitant Phase 2 · Vanda Pharmaceuticals Netherlands · Obesity

Related & competitor drugs

  1. aprepitant Alimentary tract and metabolism (A04)
  2. fosaprepitant dimeglumine Neurokinin 1 receptor antagonist
  3. elinzanetant Neurokinin 3 receptor antagonist
  4. fosnetupitant chloride hydrochloride Neurokinin 1 receptor antagonist
  5. netupitant Alimentary tract and metabolism (A04)
  6. rolapitant hydrochloride Neurokinin 1 receptor antagonist
  1. US 12318375

    Method of treatment with tradipitant

    Expires Mon May 29 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11549147

    Treatment of atopic dermatitis with tradipitant

    Expires Mon Jan 05 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11324735

    Method of treatment with tradipitant

    Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10821099

    Use of tradipitant in motion sickness

    Expires Mon Oct 29 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10772880

    Method of treatment with tradipitant

    Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10463655

    Method of treatment with tradipitant

    Expires Mon Oct 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is tradipitant?

tradipitant (NEREUS) is a neurokinin 1 receptor antagonist. Associated with Vanda Pharmaceuticals Netherlands B.V.. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for tradipitant?

NEREUS is a marketed brand name for tradipitant. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of tradipitant?

tradipitant has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.