Wednesday, July 8, 2026

Drug profile · INN

sulfisoxazole

sulfisoxazole (SULFISOXAZOLE) is a bacterial dihydropteroate synthase inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 20
Pipeline programs 0
News articles 0
Drug details — sulfisoxazole
US status
approved
Class
Route
ORAL
Patents
20
Programs
0
Data quality
0.84

Quick answer

sulfisoxazole (SULFISOXAZOLE) is a bacterial dihydropteroate synthase inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN sulfisoxazole
Brand SULFISOXAZOLE
Mechanism Bacterial dihydropteroate synthase inhibitor
Target Dihydropteroate synthase
Route ORAL
Formulation TABLET

Mechanism of action

Bacterial dihydropteroate synthase inhibitor

Primary target: Dihydropteroate synthase

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. dapsone Dihydropteroate synthase 1 inhibitor
  2. sulfamethoxazole Bacterial dihydropteroate synthase inhibitor
  3. mafenide acetate Bacterial dihydropteroate synthase inhibitor
  4. silver sulfadiazine Bacterial dihydropteroate synthase inhibitor
  5. sulfacetamide sodium Bacterial dihydropteroate synthase inhibitor
  6. sulfadiazine Bacterial dihydropteroate synthase inhibitor

Related patents

  1. US 12351561

    Crystalline (2S,4R)-5-(5'-chloro-2'-fluoro-[1,1'-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

    Expires Mon Jul 03 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11718591

    Crystalline (2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2- methylpentanoic acid and uses thereof

    Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11230536

    Crystalline (2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

    Expires Mon Jan 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11034684

    Isoxazole analogs as FXR agonists and methods of use thereof

    Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10829486

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10752599

    Crystalline (2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

    Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10597391

    Urea-containing isoxazole derivatives as FXR agonists and methods of use thereof

    Expires Mon Mar 19 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10472335

    Crystalline(2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-bipheny]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

    Expires Mon Nov 07 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10450306

    Isoxazole analogs as FXR agonists and methods of use thereof

    Expires Mon Oct 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10149836

    Isoxazole treatments for frontotemporal dementia

    Expires Mon Dec 06 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10144729

    Isoxazole analogs as FXR agonists and methods of use thereof

    Expires Mon Nov 29 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10138228

    Isoxazole derivatives as FXR agonists and methods of use therof

    Expires Mon Nov 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10100021

    Crystalline(2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

    Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10080741

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10080742

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10080743

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9855249

    Isoxazole compounds and methods for the treatment of cystic fibrosis

    Expires Mon Dec 28 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9605000

    Spiro azetidine isoxazole derivatives and their use as SSTR antagonists

    Expires Mon Mar 23 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9271965

    Crystalline forms of (R)-3-[N-(3'-chlorobiphenyl-4-ylmethyl)-N'-(3-hydroxyisoxazole-5-carbonyl)hydrazino]-2-hydroxyproprionic acid isopropyl ester

    Expires Mon Feb 25 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9221800

    Isoxazole treatments for diabetes

    Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is sulfisoxazole?

sulfisoxazole (SULFISOXAZOLE) is a bacterial dihydropteroate synthase inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for sulfisoxazole?

SULFISOXAZOLE is a marketed brand name for sulfisoxazole. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of sulfisoxazole?

sulfisoxazole has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.