Wednesday, July 8, 2026

Drug profile · INN

silver sulfadiazine

silver sulfadiazine (SILVADENE) is a bacterial dihydropteroate synthase inhibitor. Route of administration: topical. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — silver sulfadiazine
US status
approved
Class
Route
TOPICAL
Patents
0
Programs
2
Data quality
0.84

Quick answer

silver sulfadiazine (SILVADENE) is a bacterial dihydropteroate synthase inhibitor. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN silver sulfadiazine
Brand SILVADENE
Mechanism Bacterial dihydropteroate synthase inhibitor
Target Dihydropteroate synthase
Route TOPICAL
Formulation DRESSING

Mechanism of action

Bacterial dihydropteroate synthase inhibitor

Primary target: Dihydropteroate synthase

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Silver Sulfadiazine Approved · United Therapeutics Europe · Superficial Partial Thickness Burn
  2. Skin stretching device (SSD) Approved · First People's Hospital · Trauma

Related & competitor drugs

  1. dapsone Dihydropteroate synthase 1 inhibitor
  2. sulfamethoxazole Bacterial dihydropteroate synthase inhibitor
  3. mafenide acetate Bacterial dihydropteroate synthase inhibitor
  4. sulfacetamide sodium Bacterial dihydropteroate synthase inhibitor
  5. sulfadiazine Bacterial dihydropteroate synthase inhibitor
  6. sulfadiazine sodium Bacterial dihydropteroate synthase inhibitor

Frequently asked questions

What is silver sulfadiazine?

silver sulfadiazine (SILVADENE) is a bacterial dihydropteroate synthase inhibitor. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for silver sulfadiazine?

SILVADENE is a marketed brand name for silver sulfadiazine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of silver sulfadiazine?

silver sulfadiazine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.