Friday, July 10, 2026

Drug profile · INN

sulfacetamide sodium

sulfacetamide sodium (KLARON) is a bacterial dihydropteroate synthase inhibitor. Route of administration: ophthalmic. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 17
Pipeline programs 4
News articles 0
Drug details — sulfacetamide sodium
US status
approved
Class
Route
OPHTHALMIC
Patents
17
Programs
4
Data quality
0.84

Quick answer

sulfacetamide sodium (KLARON) is a bacterial dihydropteroate synthase inhibitor. Route of administration: ophthalmic. Current US regulatory status: approved.

Key facts

INN sulfacetamide sodium
Brand KLARON
Mechanism Bacterial dihydropteroate synthase inhibitor
Target Dihydropteroate synthase
Route OPHTHALMIC
Formulation LOTION

Mechanism of action

Bacterial dihydropteroate synthase inhibitor

Primary target: Dihydropteroate synthase

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. PH-10 Phase 2 · Provectus Biopharmaceuticals · Atopic Dermatitis
  2. PH-10 (0.001% Rose Bengal) Phase 2 · Provectus Biopharmaceuticals · Psoriasis
  3. PH-10 (0.002% Rose Bengal) Phase 2 · Provectus Biopharmaceuticals · Psoriasis
  4. PH-10 (rose bengal disodium 0.001%) Phase 2 · Provectus Biopharmaceuticals · Plaque Psoriasis

Related & competitor drugs

  1. dapsone Dihydropteroate synthase 1 inhibitor
  2. sulfamethoxazole Bacterial dihydropteroate synthase inhibitor
  3. mafenide acetate Bacterial dihydropteroate synthase inhibitor
  4. silver sulfadiazine Bacterial dihydropteroate synthase inhibitor
  5. sulfadiazine Bacterial dihydropteroate synthase inhibitor
  6. sulfadiazine sodium Bacterial dihydropteroate synthase inhibitor

Related patents

  1. US 12247004

    2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use

    Expires Mon Mar 06 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11802110

    2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase

    Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. CN 115348859

    Ophthalmic formulations comprising n-[5-(aminosulfonyl)-4-methyl-1, 3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl) phenyl] acetamide hemihydrate

    Expires Mon Nov 10 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11241415

    N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)-2-aminophenylacetamide derivatives agonists for the κ opioid receptor

    Expires Mon Feb 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10322107

    N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)-2-aminophenylacetamide derivatives agonists for the kappa opioid receptor

    Expires Mon Jun 13 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8980887

    2-aryl imidazo[1,2-a]pyridine-3-acetamide derivatives, preparation methods and uses thereof

    Expires Mon Mar 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7459458

    Polymorph of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

    Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7410979

    Synergistically effective combinations of dihaloacetamide compounds and interferon or ribavirin against HCV infections

    Expires Mon Aug 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7384623

    High energy phototherapeutic agents

    Expires Mon Jun 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7353829

    Methods and apparatus for multi-photon photo-activation of therapeutic agents

    Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7348429

    Process for purifying N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide(zaleplon) and crystalline forms of zaleplon accessible with the process

    Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7304069

    Hydrate of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5α]-pyrimidin-7-yl}phenyl)acetamide and processes and methods related thereto

    Expires Mon Nov 29 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 6958342

    Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

    Expires Mon Oct 20 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  14. US 6903106

    Polymorph of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

    Expires Mon Jun 02 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  15. US 6884888

    Process for the production of N-[3-(3-cyanopyrazolo[1,5-a] pyrimidin-7-yl) phenyl]-N-ethylacetamide (zaleplon)

    Expires Mon Apr 21 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  16. US 6544999

    Polymorphs of N-methyl-N-(3-{3-[2- thienylcarbonyl]-pyrazol-[1,5-&agr;]- pyrimidin-9-yl}phenyl)acetamide and compositions and methods related thereto

    Expires Mon Apr 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  17. US 6384221

    Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-&agr;]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

    Expires Mon May 02 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is sulfacetamide sodium?

sulfacetamide sodium (KLARON) is a bacterial dihydropteroate synthase inhibitor. Route of administration: ophthalmic. Current US regulatory status: approved.

What is the brand name for sulfacetamide sodium?

KLARON is a marketed brand name for sulfacetamide sodium. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of sulfacetamide sodium?

sulfacetamide sodium has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.