Wednesday, July 8, 2026

Drug profile · INN

ranibizumab

ranibizumab (LUCENTIS) is a vascular endothelial growth factor a inhibitor. Associated with Novartis Pharmaceuticals. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved NMPA: clinical trials Sensory organs (S01) S01LA04
US status approved
Patents linked 0
Pipeline programs 17
News articles 0
Drug details — ranibizumab
US status
approved
Class
Sensory organs (S01)
Route
INJECTION
Patents
0
Programs
17
Data quality
0.84

Quick answer

ranibizumab (LUCENTIS) is a vascular endothelial growth factor a inhibitor. Associated with Novartis Pharmaceuticals. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN ranibizumab
Brand LUCENTIS
Mechanism Vascular endothelial growth factor A inhibitor
Target Vascular endothelial growth factor A, long form
Therapeutic class Sensory organs (S01)
Route INJECTION
Formulation INJECTABLE
ATC code S01LA04

Mechanism of action

Vascular endothelial growth factor A inhibitor

Primary target: Vascular endothelial growth factor A, long form

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. CR213-20 Phase 3 · CuraTeQ Biologics s.r.o · wet macula degeneration
  2. CR44829 Phase 3 · HOFFMANN-LA ROCHE · Choroidal neovascularization secondary to pathologic myopia
  3. GR40549 Phase 3 · HOFFMANN-LA ROCHE · Neovascular Age-Related Macular Degeneration (nAMD)
  4. MR45625 Phase 3 · HOFFMANN-LA ROCHE · Neovascular Age-Related Macular Degeneration (nAMD)
  5. PDS Implant with Ranibizumab 100 mg/mL Phase 3 · HOFFMANN-LA ROCHE · Neovascular Age-Related Macular Degeneration
  6. RGX-314-3101/M23-409 Phase 3 · AbbVie Deutschland GmbH · Neovascular age-related macular degeneration
  7. Ranibizumab Phase 3 · Novartis India · Retinopathy of Prematurity
  8. Ranibizumab Phase 3 · Novartis India · Retinopathy of Prematurity (ROP)

Related & competitor drugs

  1. aflibercept Sensory organs (S01)
  2. atropine sulfate Sensory organs (S01)
  3. bevacizumab Antineoplastic and immunomodulating agents (L01)
  4. bevacizumab-maly Vascular endothelial growth factor A inhibitor
  5. bimatoprost Sensory organs (S01)
  6. atropine Sensory organs (S01)

Frequently asked questions

What is ranibizumab?

ranibizumab (LUCENTIS) is a vascular endothelial growth factor a inhibitor. Associated with Novartis Pharmaceuticals. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for ranibizumab?

LUCENTIS is a marketed brand name for ranibizumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ranibizumab?

ranibizumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.