Wednesday, July 8, 2026

Drug profile · INN

palonosetron hydrochloride

palonosetron hydrochloride (PALONOSETRON HYDROCHLORIDE) is a serotonin 3a (5-ht3a) receptor antagonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 1
Pipeline programs 1
News articles 0
Drug details — palonosetron hydrochloride
US status
approved
Class
Route
ORAL
Patents
1
Programs
1
Data quality
0.89

Quick answer

palonosetron hydrochloride (PALONOSETRON HYDROCHLORIDE) is a serotonin 3a (5-ht3a) receptor antagonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN palonosetron hydrochloride
Brand PALONOSETRON HYDROCHLORIDE
Mechanism Serotonin 3a (5-HT3a) receptor antagonist
Target 5-hydroxytryptamine receptor 3A
Route ORAL
Formulation INJECTABLE

Mechanism of action

Serotonin 3a (5-HT3a) receptor antagonist

Primary target: 5-hydroxytryptamine receptor 3A

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Raloxifene - Usual Phase 3 · Lxo Ireland Designated · Breast Cancer

Related & competitor drugs

  1. alosetron hydrochloride Serotonin 3a (5-HT3a) receptor antagonist
  2. granisetron Alimentary tract and metabolism (A04)
  3. granisetron hydrochloride Serotonin 3a (5-HT3a) receptor antagonist
  4. ondansetron Serotonin 3a (5-HT3a) receptor antagonist
  5. ondansetron hydrochloride Serotonin 3a (5-HT3a) receptor antagonist
  6. dolasetron mesylate Serotonin 3a (5-HT3a) receptor antagonist
  1. US 7579333

    Therapy using a combination of raloxifene and alendronate

    Expires Mon Aug 20 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is palonosetron hydrochloride?

palonosetron hydrochloride (PALONOSETRON HYDROCHLORIDE) is a serotonin 3a (5-ht3a) receptor antagonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for palonosetron hydrochloride?

PALONOSETRON HYDROCHLORIDE is a marketed brand name for palonosetron hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of palonosetron hydrochloride?

palonosetron hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.