Wednesday, July 8, 2026

Drug profile · INN

ondansetron hydrochloride

ondansetron hydrochloride (ONDANSETRON HYDROCHLORIDE) is a serotonin 3a (5-ht3a) receptor antagonist. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — ondansetron hydrochloride
US status
approved
Class
Route
INJECTION
Patents
0
Programs
2
Data quality
0.89

Quick answer

ondansetron hydrochloride (ONDANSETRON HYDROCHLORIDE) is a serotonin 3a (5-ht3a) receptor antagonist. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN ondansetron hydrochloride
Brand ONDANSETRON HYDROCHLORIDE
Mechanism Serotonin 3a (5-HT3a) receptor antagonist
Target 5-hydroxytryptamine receptor 3A
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Serotonin 3a (5-HT3a) receptor antagonist

Primary target: 5-hydroxytryptamine receptor 3A

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Fentanyl hameln 50 microgram/ml for healthy volunteers, opioid use… Approved · Disc Medicine · healthy volunteers, opioid use disorder
  2. Ondansetron (Zofran) Unknown · United Therapeutics Europe · Itching

Related & competitor drugs

  1. alosetron hydrochloride Serotonin 3a (5-HT3a) receptor antagonist
  2. granisetron Alimentary tract and metabolism (A04)
  3. granisetron hydrochloride Serotonin 3a (5-HT3a) receptor antagonist
  4. ondansetron Serotonin 3a (5-HT3a) receptor antagonist
  5. palonosetron hydrochloride Serotonin 3a (5-HT3a) receptor antagonist
  6. dolasetron mesylate Serotonin 3a (5-HT3a) receptor antagonist

Frequently asked questions

What is ondansetron hydrochloride?

ondansetron hydrochloride (ONDANSETRON HYDROCHLORIDE) is a serotonin 3a (5-ht3a) receptor antagonist. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for ondansetron hydrochloride?

ONDANSETRON HYDROCHLORIDE is a marketed brand name for ondansetron hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ondansetron hydrochloride?

ondansetron hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.