Wednesday, July 8, 2026

Drug profile · INN

ethinyl estradiol

ethinyl estradiol (LEVONORGESTREL AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL) is a estrogen receptor alpha agonist. Associated with Amneal Pharma Europe Ltd. Route of administration: oral-21. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 11
Pipeline programs 87
News articles 0
Drug details — ethinyl estradiol
US status
approved
Class
Route
ORAL-21
Patents
11
Programs
87
Data quality
0.89

Quick answer

ethinyl estradiol (LEVONORGESTREL AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL) is a estrogen receptor alpha agonist. Associated with Amneal Pharma Europe Ltd. Route of administration: oral-21. Current US regulatory status: approved.

Key facts

INN ethinyl estradiol
Brand LEVONORGESTREL AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL
Mechanism Estrogen receptor alpha agonist
Target Estrogen receptor
Route ORAL-21
Formulation TABLET, ORALLY DISINTEGRATING

Mechanism of action

Estrogen receptor alpha agonist

Primary target: Estrogen receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 1305-0069 Phase 3 · Boehringer Ingelheim · Interstitial lung diseases, Familial pulmonary fibrosis, Pul
  2. AROAPOC3-3001 Phase 3 · Arrowhead Pharmaceuticals Ireland · Familial Chylomicronemia Syndrome (FCS)
  3. AZD0780 Phase 3 · AstraZeneca · Heterozygous Familial Hypercholesterolaemia
  4. AZD0780 Placebo, AZD0780 Phase 3 · AstraZeneca · Heterozygous familial hypercholesterolaemia
  5. Alirocumab Phase 3 · Regeneron UK · Homozygous Familial Hypercholesterolemia
  6. CKJX839C12303 Phase 3 · Novartis India · Heterozygous Familial Hypercholesterolemia
  7. CKJX839C12304 Phase 3 · Novartis India · homozygous familial hypercholesterolemia
  8. Evinacumab Phase 3 · Ultragenyx UK · Homozygous Familial Hypercholesterolemia

Related & competitor drugs

  1. estradiol Estrogen receptor alpha agonist
  2. estradiol valerate Estrogen receptor alpha agonist
  3. estrogens, conjugated synthetic a Estrogen receptor agonist
  4. estropipate Estrogen receptor alpha agonist
  5. fulvestrant Antineoplastic and immunomodulating agents (L02)
  6. raloxifene Genito-urinary system and sex hormones (G03)
  1. US 12398140

    Substituted pyrrolo [2,3-d]pyrimidines for treating familial dysautonomia

    Expires Mon Aug 21 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12384797

    Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia

    Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11306155

    Methods for treating patients with heterozygous familial hypercholesterolemia (heFH) with an anti-PCSK9 antibody

    Expires Mon Apr 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11191750

    Use of mTOR inhibitors for treatment of familial adenomatous polyposis

    Expires Mon Dec 02 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11111317

    Cordyceps militaris medium polysaccharide, method for separating and purifying same, and use thereof

    Expires Mon Sep 02 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11033494

    Apparatuses containing an emulsion and methods of manufacture

    Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10544232

    Methods for treating patients with heterozygous familial hypercholesterolemia (heFH) with an anti-PCSK9 antibody

    Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10072066

    Methods and compositions for treatment of a beta thalessemia

    Expires Mon Sep 06 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8415332

    Methods of hormonal treatment utilizing ascending-dose extended cycle regimens

    Expires Mon Apr 04 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7855190

    Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration

    Expires Mon Dec 16 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 6331564

    Use of triaryl methane compounds for inhibiting unwanted cellular proliferation associated with inflammatory disease

    Expires Mon Dec 13 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is ethinyl estradiol?

ethinyl estradiol (LEVONORGESTREL AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL) is a estrogen receptor alpha agonist. Associated with Amneal Pharma Europe Ltd. Route of administration: oral-21. Current US regulatory status: approved.

What is the brand name for ethinyl estradiol?

LEVONORGESTREL AND ETHINYL ESTRADIOL AND ETHINYL ESTRADIOL is a marketed brand name for ethinyl estradiol. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ethinyl estradiol?

ethinyl estradiol has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.