Wednesday, July 8, 2026

Drug profile · INN

estropipate

estropipate (ESTROPIPATE) is a estrogen receptor alpha agonist. Associated with Teva Pharma GmbH. Route of administration: vaginal. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 20
Pipeline programs 152
News articles 0
Drug details — estropipate
US status
approved
Class
Route
VAGINAL
Patents
20
Programs
152
Data quality
0.89

Quick answer

estropipate (ESTROPIPATE) is a estrogen receptor alpha agonist. Associated with Teva Pharma GmbH. Route of administration: vaginal. Current US regulatory status: approved.

Key facts

INN estropipate
Brand ESTROPIPATE
Mechanism Estrogen receptor alpha agonist
Target Estrogen receptor
Route VAGINAL
Formulation CREAM

Mechanism of action

Estrogen receptor alpha agonist

Primary target: Estrogen receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 0.9% Sodium Chloride, JNJ-78901563 Phase 3 · Zhejiang Xianju Pharmaceutical · Invasive Extraintestinal Pathogenic Escherichia coli Disease
  2. 20220043 Phase 3 · Amgen · Osteogenesis Imperfecta
  3. 5% minoxidil foam Phase 3 · Sunshine Guojian Pharmaceutical · Androgenetic Alopecia
  4. 6-month course of antiandrogen drugs Phase 3 · First People's Hospital · Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
  5. APHP230844 Phase 3 · PARItec · Adult patients with severe cardiogenic shock on venoarterial
  6. BO41843 Phase 3 · HOFFMANN-LA ROCHE · ESTROGEN RECEPTOR-POSITIVE, HER2-NEGATIVE LOCALLY ADVANCED O
  7. Bisphosphonate Phase 3 · Ultragenyx UK · Osteogenesis Imperfecta
  8. C0371017 Phase 3 · First Biotech (Australia) · hemophilia A, severe to moderately severe hemophilia B (FIX:

Related & competitor drugs

  1. estradiol Estrogen receptor alpha agonist
  2. estradiol valerate Estrogen receptor alpha agonist
  3. estrogens, conjugated synthetic a Estrogen receptor agonist
  4. ethinyl estradiol Estrogen receptor alpha agonist
  5. fulvestrant Antineoplastic and immunomodulating agents (L02)
  6. raloxifene Genito-urinary system and sex hormones (G03)
  1. US 12410398

    Methods of human retinal progenitor cell isolation and culture

    Expires Mon Sep 04 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12398193

    Targeted replacement of endogenous T cell receptors

    Expires Mon Aug 21 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12397034

    Pharmaceutical composition for promoting neurogenesis and method for promoting neurogenesis and inhibiting senescence of brain neurons

    Expires Mon Aug 21 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12390427

    Plasminogen activator inhibitor-1 (PAI-1) inhibitor and method of use

    Expires Mon Aug 14 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12384753

    17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof

    Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12370181

    Regimens of estrogen receptor antagonists

    Expires Mon Jul 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12371747

    Methods of reducing immunogenicity against factor VIII in individuals undergoing factor VIII therapy

    Expires Mon Jul 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12370229

    Methods of treating bladder cancer

    Expires Mon Jul 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12364745

    Immunogenicity of a CpG-adjuvanted recombinant plague vaccine

    Expires Mon Jul 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12365653

    Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

    Expires Mon Jul 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12365875

    Methods for generating skeletal muscle progenitor cells

    Expires Mon Jul 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 12357617

    Discovery of novel anti-infectives for gram negative pathogens

    Expires Mon Jul 10 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12350322

    Peptide immunogens targeting interleukin 6 (IL-6) and formulations thereof for immunotherapy of diseases impacted by IL-6 dysregulation

    Expires Mon Jul 03 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12343321

    Method for ameliorating or avoiding the adverse effects of exogenous gonadotropins on reproductive performance

    Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12336982

    Compositions and methods of modulating short-chain dehydrogenase activity

    Expires Mon Jun 19 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12338439

    Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher factor) 1 (KLKB1), and kininogen 1 (KNG1) iRNA compositions and methods of use thereof

    Expires Mon Jun 19 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12312345

    Fluoroalkyl-oxadiazoles and uses thereof

    Expires Mon May 22 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12311016

    Biomarkers and immunogenic compositions for filarial parasites

    Expires Mon May 22 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12310992

    Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells

    Expires Mon May 22 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12297243

    Methods and compositions for reducing the immunogenicity of chimeric notch receptors

    Expires Mon May 08 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is estropipate?

estropipate (ESTROPIPATE) is a estrogen receptor alpha agonist. Associated with Teva Pharma GmbH. Route of administration: vaginal. Current US regulatory status: approved.

What is the brand name for estropipate?

ESTROPIPATE is a marketed brand name for estropipate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of estropipate?

estropipate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.