Wednesday, July 8, 2026

Drug profile · INN

elagolix sodium

elagolix sodium (ORILISSA) is a gonadotropin-releasing hormone receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 4
Pipeline programs 0
News articles 0
Drug details — elagolix sodium
US status
approved
Class
Route
ORAL
Patents
4
Programs
0
Data quality
0.84

Quick answer

elagolix sodium (ORILISSA) is a gonadotropin-releasing hormone receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN elagolix sodium
Brand ORILISSA
Mechanism Gonadotropin-releasing hormone receptor antagonist
Target Gonadotropin-releasing hormone receptor
Route ORAL
Formulation TABLET

Mechanism of action

Gonadotropin-releasing hormone receptor antagonist

Primary target: Gonadotropin-releasing hormone receptor

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. cetrorelix acetate Gonadotropin-releasing hormone receptor antagonist
  2. elagolix Gonadotropin-releasing hormone receptor antagonist
  3. ganirelix acetate Gonadotropin-releasing hormone receptor antagonist
  4. leuprolide acetate Gonadotropin-releasing hormone receptor agonist
  5. abarelix Gonadotropin-releasing hormone receptor antagonist
  6. degarelix acetate Gonadotropin-releasing hormone receptor antagonist

Related patents

  1. US 12102637

    Pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome or adenomyosis

    Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12083227

    Solid pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome or adenomyosis

    Expires Mon Sep 05 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11459305

    Processes for the preparation of uracil derivatives

    Expires Mon Sep 29 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7419983

    Gonadotropin-releasing hormone receptor antagonists and methods related thereto

    Expires Mon Aug 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is elagolix sodium?

elagolix sodium (ORILISSA) is a gonadotropin-releasing hormone receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for elagolix sodium?

ORILISSA is a marketed brand name for elagolix sodium. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of elagolix sodium?

elagolix sodium has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.