Wednesday, July 8, 2026

Drug profile · INN

cyclophosphamide

cyclophosphamide (CYCLONEX) is a dna inhibitor. Associated with Amdipharm Mercury (Australia) Pty Limited. Route of administration: solution. Current US regulatory status: approved.

FDA: approved TGA: approved NMPA: clinical trials
US status approved
Patents linked 8
Pipeline programs 128
News articles 0
Drug details — cyclophosphamide
US status
approved
Class
Route
SOLUTION
Patents
8
Programs
128
Data quality
0.89

Quick answer

cyclophosphamide (CYCLONEX) is a dna inhibitor. Associated with Amdipharm Mercury (Australia) Pty Limited. Route of administration: solution. Current US regulatory status: approved.

Key facts

INN cyclophosphamide
Brand CYCLONEX
Mechanism DNA inhibitor
Target DNA
Route SOLUTION
Formulation CAPSULE

Mechanism of action

DNA inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. 2019/2894 Phase 3 · George Institute for · Patients with High Risk Neuroblastoma
  2. 20190360 Phase 3 · Amgen · Newly diagnosed Philadelphia-negative B-cell precursor Acute
  3. 54767414AMY3001 Phase 3 · Janssen-Cilag International N.V · AL Amyloidosis (Newly Diagnosed Systemic AL Amyloidosis)
  4. 68284528MMY3002 Phase 3 · Janssen-Cilag International N.V · Relapsed and Lenalidomide-Refractory Multiple Myeloma
  5. 68284528MMY3004 Phase 3 · Janssen-Cilag International N.V · Multiple Myeloma
  6. ACE-CL-311 (AMPLIFY) Phase 3 · Anaxis Pharma · Previously untreated Chronic Lymphocytic Leukemia Without de
  7. ALL SCTped FORUM Phase 3 · George Institute for · Acute Lymphoblastic Leukaemia
  8. APG2575CC301 Phase 3 · Anaxis Pharma · Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocyt

Related & competitor drugs

  1. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  2. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  3. azacitidine Antineoplastic and immunomodulating agents (L01)
  4. bleomycin sulfate DNA inhibitor
  5. busulfan Antineoplastic and immunomodulating agents (L01)
  6. capecitabine Antineoplastic and immunomodulating agents (L01)
  1. US 11707434

    Method for preparing organic solvent-free lyophilized cyclophosphamide

    Expires Mon Jul 20 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8501678

    Variant activin receptor polypeptides and uses thereof

    Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8410043

    Stabilized activin IIB receptor polypeptides and uses thereof

    Expires Mon Mar 28 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8309071

    Foamy viral envelope genes

    Expires Mon Nov 08 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8293803

    Retinoid compounds and their use

    Expires Mon Oct 18 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7183334

    Low temperature molding compositions with solid thermoplastic elastomer thickeners and fiber reinforcement

    Expires Mon Feb 22 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 6433037

    Method of preparing molding compositions with fiber reinforcement and products obtained therefrom

    Expires Mon Aug 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  8. US 6103779

    Method of preparing molding compositions with fiber reinforcement and products obtained therefrom

    Expires Mon Aug 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is cyclophosphamide?

cyclophosphamide (CYCLONEX) is a dna inhibitor. Associated with Amdipharm Mercury (Australia) Pty Limited. Route of administration: solution. Current US regulatory status: approved.

What is the brand name for cyclophosphamide?

CYCLONEX is a marketed brand name for cyclophosphamide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of cyclophosphamide?

cyclophosphamide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.