Wednesday, July 8, 2026

Drug profile · INN

acyclovir

acyclovir (ZOVIRAX) is a human herpesvirus 1 dna polymerase inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: ophthalmic. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 6
Pipeline programs 10
News articles 0
Drug details — acyclovir
US status
approved
Class
Route
OPHTHALMIC
Patents
6
Programs
10
Data quality
0.89

Quick answer

acyclovir (ZOVIRAX) is a human herpesvirus 1 dna polymerase inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: ophthalmic. Current US regulatory status: approved.

Key facts

INN acyclovir
Brand ZOVIRAX
Mechanism Human herpesvirus 1 DNA polymerase inhibitor
Target DNA polymerase catalytic subunit
Route OPHTHALMIC
Formulation CAPSULE

Mechanism of action

Human herpesvirus 1 DNA polymerase inhibitor

Primary target: DNA polymerase catalytic subunit

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Acyclovir Phase 3 · BRIGHT MINDS BIOSCIENCES · HIV Infections
  2. Aglatimagene besadenovec + valacyclovir Phase 3 · Candel Therapeutics · Prostate Cancer
  3. OP-LIPC02 Phase 3 · Anaxis Pharma · Recurrent herpes labialis (RHL)
  4. acyclovir Phase 3 · Ultragenyx UK · Herpes Simplex
  5. VACl Phase 2 · First People's Hospital · Acute Myeloid Leukemia, Adult
  6. aglatimagene besadenovec + valacyclovir Phase 2 · Candel Therapeutics · Prostate Cancer Patients Treated by Radiotherapy
  7. AdV-tk + valacyclovir Phase 1 · Candel Therapeutics · Malignant Pleural Effusion
  8. CAN-2409 + valacyclovir Phase 1 · Candel Therapeutics · Lung Cancer

Related & competitor drugs

  1. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  2. famciclovir Human herpesvirus 1 DNA polymerase inhibitor
  3. foscarnet sodium Human herpesvirus 1 DNA polymerase inhibitor
  4. ganciclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  5. penciclovir Human herpesvirus 1 DNA polymerase inhibitor
  6. valacyclovir hydrochloride Human herpesvirus 1 DNA polymerase inhibitor
  1. US 11439585

    Programmable pharmaceutical compositions for chrono drug release

    Expires Mon Sep 08 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11166906

    Programmable pharmaceutical compositions for chrono drug release

    Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11154494

    Programmable pharmaceutical compositions for chrono drug release

    Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10052467

    Applicator for applying a fluid to a surface

    Expires Mon Aug 16 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9629805

    Stabilization of moisture-sensitive drugs

    Expires Mon Apr 20 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9227044

    Applicator for applying a fluid to a surface

    Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is acyclovir?

acyclovir (ZOVIRAX) is a human herpesvirus 1 dna polymerase inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: ophthalmic. Current US regulatory status: approved.

What is the brand name for acyclovir?

ZOVIRAX is a marketed brand name for acyclovir. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of acyclovir?

acyclovir has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.