Wednesday, July 8, 2026

pharma · Pancreatic Adenocarcinoma · Cancer · ACTU

Actuate Therapeutics

Actuate Therapeutics drug portfolio — 11 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

1751 River Run, Suite 400, Fort Worth, Texas 76107, US HQ
2015 Founded
16 Employees
Public company Type
ACTU · NYSE Ticker
Company details
Status
Public
HQ
1751 River Run, Suite 400, Fort Worth, Texas 76107, US
Founded
2015
Employees
16
Programs
12
Drugs
11
Patents
7
Intelligence · Drug Pipeline

Actuate Therapeutics pipeline

Portfolio lens on 11 drugs and development assets — regulatory status, targets, and deep links to NovaPharmaNews drug profiles.

Actuate Therapeutics drug portfolio — 11 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Drug portfolio

11 compounds
  1. Development asset linked to Actuate Therapeutics in public FDA and regional records. Molecular target: Tubulin.

    Target
    Tubulin
    Mechanism
    Tubulin inhibitor
  2. US regulatory status: approved. Mechanism: DNA polymerase (alpha/delta/epsilon) inhibitor.

    Mechanism
    DNA polymerase (alpha/delta/epsilon) inhibitor
  3. Development asset linked to Actuate Therapeutics in public FDA and regional records.

  4. Development asset linked to Actuate Therapeutics in public FDA and regional records.

  5. Development asset linked to Actuate Therapeutics in public FDA and regional records. Molecular target: Progesterone receptor.

    Target
    Progesterone receptor
    Mechanism
    Progesterone receptor agonist
  6. US regulatory status: approved. Molecular target: Progesterone receptor.

    Target
    Progesterone receptor
    Mechanism
    Progesterone receptor agonist
  7. Development asset linked to Actuate Therapeutics in public FDA and regional records.

  8. retifanlimab

    Antineoplastic and immunomodulating agents (L01)

    Antineoplastic and immunomodulating agents (L01) compound in Actuate Therapeutics's portfolio. Molecular target: Programmed cell death protein 1.

    Target
    Programmed cell death protein 1
    Mechanism
    Programmed cell death protein 1 antagonist
  9. US regulatory status: approved. Molecular target: Programmed cell death protein 1.

    Target
    Programmed cell death protein 1
    Mechanism
    Programmed cell death protein 1 antagonist
  10. ruxolitinib

    Dermatologicals (D11)

    US regulatory status: approved. Mechanism: Tyrosine-protein kinase JAK2 inhibitor.

    Mechanism
    Tyrosine-protein kinase JAK2 inhibitor
  11. Development asset linked to Actuate Therapeutics in public FDA and regional records.