Friday, July 10, 2026

Drug profile · INN

retifanlimab-dlwr

retifanlimab-dlwr (ZYNYZ) is a programmed cell death protein 1 antagonist. Route of administration: intravenous. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 4
Pipeline programs 1
News articles 0
Drug details — retifanlimab-dlwr
US status
approved
Class
Route
INTRAVENOUS
Patents
4
Programs
1
Data quality
0.84

Quick answer

retifanlimab-dlwr (ZYNYZ) is a programmed cell death protein 1 antagonist. Route of administration: intravenous. Current US regulatory status: approved.

Key facts

INN retifanlimab-dlwr
Brand ZYNYZ
Mechanism Programmed cell death protein 1 antagonist
Target Programmed cell death protein 1
Route INTRAVENOUS
Formulation INJECTABLE

Mechanism of action

Programmed cell death protein 1 antagonist

Primary target: Programmed cell death protein 1

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Retifanlimab Phase 1 · Actuate Therapeutics · Pancreatic Adenocarcinoma

Related & competitor drugs

  1. cemiplimab Antineoplastic and immunomodulating agents (L01)
  2. cemiplimab-rwlc Programmed cell death protein 1 inhibitor
  3. tislelizumab Antineoplastic and immunomodulating agents (L01)
  4. toripalimab-tpzi Programmed cell death protein 1 antagonist
  5. dostarlimab-gxly Programmed cell death protein 1 antagonist
  6. islelizumab-jsgr Programmed cell death protein 1 inhibitor

Related patents

  1. US 12145943

    Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12116374

    Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Oct 10 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11407759

    Solid forms of 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Aug 04 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11136334

    Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Sep 30 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is retifanlimab-dlwr?

retifanlimab-dlwr (ZYNYZ) is a programmed cell death protein 1 antagonist. Route of administration: intravenous. Current US regulatory status: approved.

What is the brand name for retifanlimab-dlwr?

ZYNYZ is a marketed brand name for retifanlimab-dlwr. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of retifanlimab-dlwr?

retifanlimab-dlwr has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.