Wednesday, July 8, 2026

Drug profile · INN

megestrol acetate

megestrol acetate (MEGESTROL ACETATE) is a progesterone receptor agonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 4
Pipeline programs 4
News articles 0
Drug details — megestrol acetate
US status
approved
Class
Route
ORAL
Patents
4
Programs
4
Data quality
0.89

Quick answer

megestrol acetate (MEGESTROL ACETATE) is a progesterone receptor agonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN megestrol acetate
Brand MEGESTROL ACETATE
Mechanism Progesterone receptor agonist
Target Progesterone receptor
Route ORAL
Formulation TABLET

Mechanism of action

Progesterone receptor agonist

Primary target: Progesterone receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Nano-crystalline Megestrol Acetate Oral Suspension Phase 3 · Chinese Academy of · Extensive-stage Small Cell Lung Cancer (ES-SCLC)
  2. megestrol acetate oral suspension + serplulimab + SOX Phase 2 · First People's Hospital · Stage III Gastric Cancer
  3. Megestrol acetate Unknown · Actuate Therapeutics · HIV Infections
  4. megestrol Unknown · Ultragenyx UK · Acquired Immunodeficiency Syndrome

Related & competitor drugs

  1. desogestrel Progesterone receptor agonist
  2. medroxyprogesterone acetate Progesterone receptor agonist
  3. norethindrone Progesterone receptor agonist
  4. norethindrone acetate Progesterone receptor agonist
  5. progesterone Progesterone receptor agonist
  6. ulipristal acetate Genito-urinary system and sex hormones (G03)
  1. US 12145943

    Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12116374

    Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Oct 10 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11407759

    Solid forms of 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Aug 04 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11136334

    Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

    Expires Mon Sep 30 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is megestrol acetate?

megestrol acetate (MEGESTROL ACETATE) is a progesterone receptor agonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for megestrol acetate?

MEGESTROL ACETATE is a marketed brand name for megestrol acetate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of megestrol acetate?

megestrol acetate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.