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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Liposomal Annamycin

    Moleculin Biotech

    Leukemia, Myeloid, Acute

    phase 2 small molecule completed

    3 trials

  2. Liposomal Annamycin (L-Annamycin)

    Moleculin Biotech

    Sarcoma,Soft Tissue

    phase 2 small molecule completed

    1 trial

  3. Liposomal Bupivacaine

    United Therapeutics Europe Ltd

    Femoral Fractures

    phase 2 small molecule terminated

    1 trial

  4. Liposomal Irinotecan

    United Therapeutics Europe Ltd

    Oncology

    phase 2 small molecule completed

    1 trial

  5. Liposomal bupivacaine

    United Therapeutics Europe Ltd

    Blunt Chest Wall Trauma

    phase 2 small molecule completed

    1 trial

  6. Liposomal doxorubicin hydrochloride

    Teva Pharma GmbH

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  7. Liposomal irinotecan

    The First People's Hospital of Lianyungang

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial

  8. Liposome bupivacaine

    Pacira Ireland Limited

    Hallux Valgus (Bunions)

    phase 2 small molecule completed

    1 trial

  9. Liposome bupivacaine + bupivacaine

    Pacira Ireland Limited

    Dupuytren's Contracture of the Hand (Viking's Disease)

    phase 2 small molecule completed

    1 trial

  10. Liposome-encapsulated Daunorubicin-Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome

    phase 2 small molecule active

    1 trial

  11. Liposome-encapsulated Daunorubicin-Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Essential Thrombocythemia

    phase 2 small molecule terminated

    1 trial

  12. Liposome-encapsulated Daunorubicin-Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia

    phase 2 small molecule active

    2 trials

  13. Liposorber LA-15 System

    Hospital Authority, Hong Kong

    Cholesterol Embolism

    phase 2 other active

    1 trial

  14. Liposuction

    The First People's Hospital of Lianyungang

    Anterior Cruciate Ligament Partial Rupture

    phase 2 other active

    1 trial

  15. Lipotecan

    Taiwan Liposome Company

    HepatoCellular Carcinoma

    phase 2 small molecule terminated

    1 trial

  16. Liraglutide Pen Injector

    BRIGHT MINDS BIOSCIENCES INC.

    Opiate Substitution Treatment

    phase 2 small molecule completed

    1 trial

  17. Lisdexamfetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial

  18. Lisocabtagene maraleucel

    Celgene Europe Limited

    Relapsed or refractory indolent B-cell Non-Hodgkin Lymphoma (NHL)

    phase 2 small molecule active

    1 trial

  19. Lithium Carbonate

    NORTHWEST BIOTHERAPEUTICS INC

    Major Depressive Disorder

    phase 2 small molecule completed

    1 trial

  20. Lithium Carbonate

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neuropathic Pain

    phase 2 small molecule completed

    1 trial

  21. Lithium Carbonate

    BRIGHT MINDS BIOSCIENCES INC.

    Frontotemporal Dementia (FTD)

    phase 2 small molecule completed

    1 trial

  22. Live attenuated Japanese encephalitis virus; Yellow fever virus

    Sanofi Pasteur

    Japanese Encephalitis

    phase 2 mab completed

    1 trial

  23. Loc-R01: Randomized Phase IB/II Study of escalating doses of Lenalidomide and Ibrutinib in association with R-MPV as a targeted induction treatment for patients aged 18 to 60 (up to 65 for phase II) with a newly diagnosed Primary Central Nervous System Lymphoma

    The George Institute

    Primary Central Nervous System Lymphoma (PCNSL)

    phase 2 other active

    1 trial

  24. Locally Sourced 0.9% Sodium Chloride

    GlaxoSmithKline

    Dermatitis, Atopic

    phase 2 small molecule active

    1 trial

  25. Locally Sourced 0.9% Sodium Chloride

    GlaxoSmithKline

    Dermatitis, Atopic

    phase 2 small molecule active

    1 trial

  26. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Dependence

    phase 2 small molecule completed

    1 trial

  27. Lofexidine

    United Therapeutics Europe Ltd

    Post Traumatic Stress Disorder

    phase 2 small molecule completed

    1 trial

  28. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-use Disorder

    phase 2 small molecule completed

    1 trial

  29. Lomustine "medac" 40 mg, Fibromun

    Philogen S.p.A.

    Glioblastoma

    phase 2 small molecule active

    1 trial

  30. Loncastuximab Tesirine

    ADC Therapeutics SA

    Relapsed or Refractory Large B-cell Lymphoma

    phase 2 small molecule active

    1 trial

  31. Loncastuximab Tesirine

    ADC Therapeutics SA

    Diffuse Large B-cell Lymphoma

    phase 2 small molecule active

    4 trials

  32. Loncastuximab Tesirine

    ADC Therapeutics SA

    Waldenstrom Macroglobulinemia

    phase 2 small molecule active

    1 trial

  33. Loncastuximab Tesirine

    ADC Therapeutics SA

    Relapsed Follicular Lymphoma

    phase 2 small molecule terminated

    1 trial

  34. Loncastuximab tesirine

    ADC Therapeutics SA

    Diffuse Large B-Cell Lymphoma Refractory

    phase 2 small molecule completed

    1 trial

  35. Loncastuximab tesirine

    ADC Therapeutics SA

    Post-transplant Lymphoproliferative Disorder

    phase 2 small molecule active

    1 trial

  36. Loncastuximab tesirine

    ADC Therapeutics SA

    Follicular Lymphoma

    phase 2 small molecule active

    1 trial

  37. Loncastuximab tesirine 150 µg/Kg

    ADC Therapeutics SA

    Marginal Zone Lymphoma

    phase 2 small molecule active

    1 trial

  38. Lonsurf 15 mg/6.14 mg film-coated tablets, IRINOTECAN, Bemarituzumab, PACLITAXEL, RAMUCIRUMAB

    The George Institute

    FGFR2b-positive, advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction

    phase 2 small molecule active

    1 trial

  39. Loratadina NORMON 10 mg Comprimidos EFG

    The George Institute

    Effect of loratadine in patients with lymphangioleiomyomatosis

    phase 2 small molecule active

    1 trial

  40. Loratadine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rhinitis, Allergic, Perennial

    phase 2 small molecule completed

    1 trial

  41. Lorazepam

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 small molecule terminated

    1 trial

  42. Lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 2 small molecule completed

    1 trial

  43. Lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  44. Lorundrostat

    Mineralys Therapeutics

    Obstructive Sleep Apnea

    phase 2 small molecule completed

    1 trial

  45. Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD

    Mineralys Therapeutics

    Chronic Kidney Disease

    phase 2 small molecule completed

    1 trial

  46. Lorviqua 100 mg film-coated tablets, Lorviqua 25 mg film-coated tablets

    CERO THERAPEUTICS HOLDINGS, INC.

    Advanced ROS1-positive non-small cell lung cancer

    phase 2 small molecule active

    1 trial

  47. Losartan

    United Therapeutics Europe Ltd

    Hip Osteoarthritis

    phase 2 small molecule terminated

    1 trial

  48. Losartan Potassium

    Ultragenyx UK Limited

    Eosinophilic Esophagitis

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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