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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Lenvatinib, quavonlimab, TRETINOIN, KEYTRUDA 25 mg/mL concentrate for solution for infusion, Lenvatinib, vibostolimab

    Merck Sharp and Dohme

    PD-1 refractory melanoma

    phase 2 small molecule active

    1 trial

  2. Lenvima 4 mg Oral Capsule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial

  3. Letrozole

    United Therapeutics Europe Ltd

    Lymphangioleiomyomatosis

    phase 2 small molecule completed

    1 trial

  4. Letrozole

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  5. Letrozole

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Uterine Cervical Neoplasms

    phase 2 small molecule active

    1 trial

  6. Letrozole SanoSwiss 2,5 mg plėvele dengtos tabletės

    Pfizer Australia Pty Ltd

    HORMONE RECEPTOR-POSITIVE, HER2-NEGATIVE BREAST CANCER

    phase 2 small molecule active

    1 trial

  7. Letybo® 50 Einheiten Pulver zur Herstellung einer Injektionslösung, Letybo 50 Einheiten Pulver zur Herstellung einer Injektionslösung

    Lacuna Pharma Pty Ltd

    Moderate and severe horizontal forehead lines.

    phase 2 small molecule active

    1 trial

  8. Leucovorin

    Cardiff Oncology

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial

  9. Leucovorin 10 mg/ml Lösung zur Injektion/ Infusion, TAXOTERE 20 mg/1 ml concentrate for solution for infusion, medoxa 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung, IMFINZI 50 mg/mL concentrate for solution for infusion., 5-FU medac 50 mg/ml, Injektionslösung

    The George Institute

    T1-T2N0 esophageal adenocarcinoma including gastroesophageal junction (GEJ) with indication for radical surgery

    phase 2 small molecule active

    1 trial

  10. Leukine, Lynparza 100 mg film-coated tablets, IMFINZI 50 mg/mL concentrate for solution for infusion., Lynparza 150 mg film-coated tablets, UV1

    Nordic Bioscience A/S

    Ovarian cancer

    phase 2 small molecule active

    1 trial

  11. Leukine, OXALIPLATIN, ENDOXAN 50 mg, comprimé enrobé, STC-1010, FLUOROURACIL, CALCIUM FOLINATE

    Lacuna Pharma Pty Ltd

    Unresectable locally advanced or metastatic colorectal cancer

    phase 2 small molecule active

    1 trial

  12. Leukocyte-Poor Platelet Rich Plasma (LP-PRP)

    United Therapeutics Europe Ltd

    Osteoarthritis, Knee

    phase 2 mab active

    1 trial

  13. Leuprolide acetate

    Voyager Therapeutics

    Alzheimer Disease

    phase 2 small molecule completed

    2 trials

  14. Leuprolide or goserelin

    NORTHWEST BIOTHERAPEUTICS INC

    Cancer

    phase 2 small molecule completed

    1 trial

  15. Leuprorelin

    Takeda

    Prostatic Neoplasms

    phase 2 small molecule completed

    1 trial

  16. Leuprorelin (GF)

    Takeda

    Uterine Fibroids

    phase 2 small molecule completed

    1 trial

  17. Levact 2,5 mg/ml, polvo para concentrado para solución para perfusión., Beneflur10 mg comprimidos recubiertos con película, RoActemra 20 mg/mL concentrate for solution for infusion, Genoxal 200 mg polvo para solución inyectable y para perfusión, HSP-CAR19M

    The George Institute

    Relapsed/refractory large B-cell non-Hodgkin lymphoma, mantle cell lymphoma, and follicular lymphoma

    phase 2 small molecule active

    1 trial

  18. Levoleucovorin Calcium

    United Therapeutics Europe Ltd

    Autism Spectrum Disorder

    phase 2 small molecule active

    1 trial

  19. Levosimendan

    TENAX THERAPEUTICS, INC.

    Hypertension Pulmonary Secondary Heart Failure

    phase 2 small molecule completed

    1 trial

  20. Levosimendan

    TENAX THERAPEUTICS, INC.

    Hypertension Pulmonary Secondary

    phase 2 small molecule completed

    1 trial

  21. Levothyroxine sodium new formulation

    Takeda

    Hypothyroidism

    phase 2 small molecule completed

    1 trial

  22. LiPlaCis

    Allarity Therapeutics

    Phase 1: Advanced or Refractory Solid Tumours

    phase 2 small molecule completed

    1 trial

  23. Libmeldy 2-10 x 10^6 cells/mL dispersion for infusion

    Orchard Therapeutics (Netherlands) B.V.

    Metachromatic Leukodystrophy (MLD)

    phase 2 small molecule active

    1 trial

  24. Lidocaine HCl

    BRIGHT MINDS BIOSCIENCES INC.

    Postherpetic Neuralgia

    phase 2 small molecule active

    1 trial

  25. Lidocaine Hydrochloride, Injectable

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Postoperative Chronic Pain

    phase 2 small molecule active

    1 trial

  26. Lidocaína B. Braun 20 mg/ml solución inyectable, Suero Fisiológico Braun 0,9% disolvente para uso parenteral Cloruro de sodio

    The George Institute

    headache pain related to SAH, Spontaneous subarachnoid hemorrhage

    phase 2 small molecule active

    1 trial

  27. Lifei Qingchang Granules

    The First People's Hospital of Lianyungang

    Bronchiectasis

    phase 2 small molecule active

    1 trial

  28. Lifileucel

    Iovance Biotherapeutics B.V.

    Melanoma (Skin Cancer)

    phase 2 mab active

    1 trial

  29. Lifileucel

    Iovance Biotherapeutics B.V.

    Metastatic Melanoma

    phase 2 mab completed

    2 trials

  30. Lifileucel

    Iovance Biotherapeutics B.V.

    Endometrial Cancer

    phase 2 mab active

    1 trial

  31. Lifitegrast

    Takeda

    Dry Eye

    phase 2 small molecule completed

    1 trial

  32. Lifitegrast

    Takeda

    Allergic Conjunctivitis

    phase 2 small molecule completed

    1 trial

  33. Light-activated AU-011

    Aura Biosciences

    Uveal Melanoma

    phase 2 small molecule completed

    1 trial

  34. Linaclotide 145 micrograms

    IRONWOOD PHARMACEUTICALS INC

    Opioid-Induced Constipation

    phase 2 small molecule completed

    1 trial

  35. Linaclotide Acetate

    IRONWOOD PHARMACEUTICALS INC

    Irritable Bowel Syndrome With Constipation

    phase 2 small molecule completed

    1 trial

  36. Linaclotide Dose A

    IRONWOOD PHARMACEUTICALS INC

    Irritable Bowel Syndrome With Constipation

    phase 2 small molecule terminated

    1 trial

  37. Linezolid

    BRIGHT MINDS BIOSCIENCES INC.

    Pulmonary Tuberculosis

    phase 2 small molecule completed

    1 trial

  38. Linezolid

    BRIGHT MINDS BIOSCIENCES INC.

    Tuberculosis, Meningeal

    phase 2 small molecule completed

    1 trial

  39. Linperlisib combination with obinutuzumab

    The First People's Hospital of Lianyungang

    Lymphoma

    phase 2 small molecule active

    1 trial

  40. Lintuzumab-Ac225

    Actinium Pharmaceuticals

    Acute Myeloid Leukemia

    phase 2 mab active

    2 trials

  41. Linvoseltamab

    Regeneron UK Limited

    Relapsed/Refractory Systemic Light Chain Amyloidosis

    phase 2 small molecule active

    1 trial

  42. Linvoseltamab

    Regeneron UK Limited

    Smoldering Multiple Myeloma (SMM)

    phase 2 small molecule active

    1 trial

  43. Linvoseltamab

    Regeneron UK Limited

    Relapsed/Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial

  44. Linvoseltamab

    Regeneron UK Limited

    Recurrent Multiple Myeloma

    phase 2 mab active

    1 trial

  45. Linvoseltamab

    Regeneron UK Limited

    Monoclonal Gammopathy of Undetermined Significance (MGUS)

    phase 2 small molecule active

    1 trial

  46. Linvoseltamab, Diphenhydramine Hydrochloride 25 mg Tablets, RoActemra 20 mg/mL concentrate for solution for infusion, Dexamethasone 4 mg tablets, Dexamethasone phosphate 4 mg/ml solution for injection/infusion, Paracetamol 500 mg Film-Coated Tablets

    Lacuna Pharma Pty Ltd

    High-Risk Monoclonal Gammopathy of Undetermined Significance; Non-High-Risk Smoldering Multiple Myeloma

    phase 2 small molecule active

    1 trial

  47. Linvoseltamab, Linvoseltamab, RoActemra 20 mg/mL concentrate for solution for infusion, Dexamethasone phosphate 4 mg/ml solution for injection/infusion, Diphenhydramine Hydrochloride 25 mg Tablets, Paracetamol 500mg Tablets, REGN88, Dexamethasone 2mg Tablets

    Lacuna Pharma Pty Ltd

    Relapsed or Refractory Systemic Light Chain Amyloidosis

    phase 2 small molecule active

    1 trial

  48. Lipid Lowering Medication

    Grace Therapeutics

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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