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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Humanized immunoglobulin G1 (IgG1) kappa monoclonal antibody (mAb) targeting PAUF

    Lacuna Pharma Pty Ltd

    Advanced and/or metastatic pancreatic adenocarcinoma

    phase 2 small molecule active

    1 trial

  2. Humira 40 mg solution for injection in pre-filled syringe

    Disc Medicine

    Inflammatory Bowel Disease (IBD)

    phase 2 small molecule active

    1 trial

  3. Humira 40 mg solution for injection in pre-filled syringe, Lutikizumab, Humira 80 mg solution for injection in pre-filled syringe, Humira 40 mg solution for injection in pre-filled syringe, Lutikizumab, Humira 40 mg solution for injection in pre-filled syringe, Humira 40 mg solution for injection in pre-filled syringe

    AbbVie Deutschland GmbH & Co. KG

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  4. Huperzine A, Huperzine A, Capsules, Huperzine A

    SUPERNUS PHARMACEUTICALS, INC.

    Focal Onset Seizures

    phase 2 small molecule active

    1 trial

  5. Huzhang granule

    Universal Integrated

    Gouty Arthritis

    phase 2 small molecule active

    1 trial

  6. Hyaluronidase

    Amphastar France Pharmaceuticals

    Allergic Skin Reaction

    phase 2 small molecule completed

    1 trial

  7. Hydrocortisone Modified Release Capsules

    NEUROCRINE BIOSCIENCES INC

    Endocrine Disease

    phase 2 small molecule completed

    1 trial

  8. Hydrocortisone acetate and lidocaine hydrochloride

    CITIUS ONCOLOGY, INC.

    Hemorrhoids

    phase 2 small molecule completed

    1 trial

  9. Hydrogel of spirulina-derived exosomes.

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation-induced Esophagitis

    phase 2 small molecule active

    1 trial

  10. Hydrogen Peroxide

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 2 small molecule active

    1 trial

  11. Hydroxycarbamid

    BRIGHT MINDS BIOSCIENCES INC.

    Central Retinal Vein Occlusion, Non-Ischemic

    phase 2 small molecule active

    1 trial

  12. Hydroxychloroquine (HCQ)

    Teva Pharma GmbH

    COVID-19

    phase 2 small molecule terminated

    1 trial

  13. Hydroxyproline and Leucine

    Ultragenyx UK Limited

    Hyperoxaluria

    phase 2 small molecule completed

    1 trial

  14. Hydroxypropyl Guar Galactomannan

    Alcon Laboratories (Australia) Pty Ltd

    Dry Eye Disease

    phase 2 small molecule completed

    1 trial

  15. Hydroxyurea

    Sana Biotechnology

    Thalassemia, Beta

    phase 2 small molecule active

    1 trial

  16. Hyperbaric Oxygen Therapy

    Summit Therapeutics

    TBI Traumatic Brain Injury

    phase 2 small molecule active

    1 trial

  17. Hyperimmune plasma

    Lxo Ireland Designated Activity Company

    SARS-CoV 2

    phase 2 mab completed

    1 trial

  18. Hyperpolarized 129Xenon gas

    United Therapeutics Europe Ltd

    Pulmonary Vascular Disease

    phase 2 small molecule completed

    1 trial

  19. Hyperpolarized 13C-Pyruvate injection

    Hospital Authority, Hong Kong

    Gynecologic Cancer

    phase 2 small molecule active

    1 trial

  20. Hyperpolarized Xe129

    Regeneron UK Limited

    Pulmonary Artery Hypertension

    phase 2 small molecule terminated

    1 trial

  21. Hypofractionated radiation/chemotherapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-small Cell Lung Cancer

    phase 2 other completed

    1 trial

  22. I-124-CLR1404

    Cellectar Biosciences

    Glioblastoma

    phase 2 small molecule terminated

    1 trial

  23. I-131-CLR1404 Injection

    Cellectar Biosciences

    Glioma

    phase 2 small molecule terminated

    1 trial

  24. IAH0968

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Solid Tumor

    phase 2 mab active

    1 trial

  25. IAP0971

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Bladder Cancer

    phase 2 small molecule active

    1 trial

  26. IAP0971

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Malignant Tumors

    phase 2 small molecule active

    1 trial

  27. IBB0979

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Malignant Tumors

    phase 2 small molecule active

    1 trial

  28. IBB0979

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  29. IBD0333

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    MTD

    phase 2 mab active

    1 trial

  30. IBI3016

    Innovent Biologics (Suzhou) Co.

    Hypertension

    phase 2 small molecule active

    2 trials

  31. IBI363

    The First People's Hospital of Lianyungang

    Advan'ce'd

    phase 2 small molecule active

    1 trial

  32. IBI363

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  33. IBRANCE 125 mg hard capsules, IBRANCE 125 mg hard capsules, IBRANCE 125 mg hard capsules, Faslodex 250 mg solution for injection., JZP598

    Jazz Pharmaceuticals Ireland Limited

    Breast cancer patients including those with locally advanced (unresectable) or metastatic HER2-positive, HR-positive breast cancer

    phase 2 small molecule active

    1 trial

  34. IBRANCE 75 mg hard capsules, EXEMESTANE, IBRANCE 125 mg hard capsules, IBRANCE 100 mg hard capsules, IBRANCE 75 mg film-coated tablets, IBRANCE 125 mg hard capsules, IBRANCE 75 mg film-coated tablets, TAMOXIFEN, IBRANCE 75 mg film-coated tablets, IBRANCE 100 mg film-coated tablets, IBRANCE 125 mg film-coated tablets, IBRANCE 125 mg hard capsules, ANASTROZOLE, IBRANCE 75 mg hard capsules, CYCLOPHOSPHAMIDE, DOCETAXEL, IBRANCE 100 mg hard capsules, IBRANCE 100 mg film-coated tablets, IBRANCE 100 mg hard capsul

    Ningbo Cancer Hospital

    Localized ER+ breast cancer

    phase 2 small molecule active

    1 trial

  35. IBRUTINIB

    Fondazione Telethon ETS

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or CLL-like monoclonal B-cell lymphocytosis

    phase 2 small molecule active

    1 trial

  36. IBUPROFEN , DEXAMETHASONE , FAMOTIDINE , SODIUM CHLORIDE , mRNA-3927, PARACETAMOL , CETIRIZINE

    Moderna Biotech Spain

    Propionic Acidemia

    phase 2 small molecule active

    1 trial

  37. ICP-022

    Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    1 trial

  38. ICP-022

    Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial

  39. IDARUBICIN, FLUDARABINE, CYTARABINE, DAUNORUBICIN, MITOXANTRONE, ETOPOSIDE, PKC412

    Novartis Pharmaceuticals

    untreated FLT3-mutated Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial

  40. IDE574

    IDEAYA Biosciences

    ER+, HER 2- Breast Cancer

    phase 2 small molecule active

    1 trial

  41. IDE849

    IDEAYA Biosciences

    Small-cell Lung Cancer

    phase 2 small molecule active

    1 trial

  42. IDOR-1117-2520 matching placebo

    Lacuna Pharma Pty Ltd

    Moderate to severe chronic plaque psoriasis

    phase 2 small molecule active

    1 trial

  43. IDP-121 Concentrate for solution for infusion 3 mg/mL

    Disc Medicine

    Unresectable/metastatic Small cell Lung Cancer (SCLC)

    phase 2 small molecule active

    1 trial

  44. IDP-121 Concentrate for solution for infusion 3 mg/mL

    Disc Medicine

    Chronic lymphocytic leukemia (CLL), Any type of B-cell lymphomas, Multiple myeloma (MM)

    phase 2 small molecule active

    1 trial

  45. IFOSFAMIDE , MabThera 500 mg concentrate for solution for infusion, ETOPOSIDE , Gazyvaro 1,000 mg concentrate for solution for infusion., CD20 CD3 TCB, RoActemra 20 mg/mL concentrate for solution for infusion, CARBOPLATIN

    Hoffmann-La Roche

    CD20 positive B-Cell Non-Hodgkin Lymphoma (NHL)

    phase 2 small molecule active

    1 trial

  46. IFOSFAMIDE, CISPLATIN, PACLITAXEL, METHYLPREDNISOLONE, RANITIDINE, MESNA, APREPITANT, DEXCHLORPHENIRAMINE MALEATE

    Ningbo Cancer Hospital

    Penis carcinoma

    phase 2 small molecule active

    1 trial

  47. IGEV

    Fudan University

    Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial

  48. IL-15-armored CAR-T cells

    The First People's Hospital of Lianyungang

    Relapsed/Refractory Multiple Myeloma

    phase 2 mab active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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