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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Page 47 of 151

  1. EPI-321

    Biotech Pharmaceutical Co.,

    Facioscapulohumeral Muscular Dystrophy

    phase 2 mab active

    1 trial

  2. EPI-589

    PTC THERAPEUTICS, INC.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial

  3. EPI-7386, Xtandi - 40 mg soft capsules

    Lacuna Pharma Pty Ltd

    Metastatic castration-resistant prostate cancer

    phase 2 small molecule active

    1 trial

  4. EPI-743

    PTC THERAPEUTICS, INC.

    Leigh Syndrome

    phase 2 small molecule completed

    1 trial

  5. EPINEPHRINE , Briquilimab

    Jasper Therapeutics

    Chronic Inducible Urticaria

    phase 2 small molecule active

    1 trial

  6. EPINEPHRINE NASAL SPRAY, Placebo Nasal Spray, EPINEPHRINE NASAL SPRAY

    Ars Pharmaceuticals Irl Limited

    Chronic Spontaneous Urticaria (CSU)

    phase 2 small molecule active

    1 trial

  7. EPLERENONE

    The George Institute

    Heart failure with reduced ejection fraction in combination with severe chronic kidney disease

    phase 2 small molecule active

    1 trial

  8. ER004

    Pierre Fabre Medicament

    X-linked hypohidrotic ectodermal dysplasia (XLHED)

    phase 2 small molecule active

    1 trial

  9. ETC-1002

    Esperion Therapeutics

    Hyperlipidemia

    phase 2 small molecule completed

    2 trials

  10. ETC-1002

    Esperion Therapeutics

    Dyslipidemia

    phase 2 small molecule completed

    1 trial

  11. ETIDRONATE DISODIUM ORAL CAPSULES 400 MG PLACEBO, ETIDRONATE DISODIUM ORAL CAPSULES 400 MG

    Disc Medicine

    Fahr's disease, Fahr's syndrome

    phase 2 small molecule active

    1 trial

  12. ETOPOSIDE TEVA 20 mg/ml, solution à diluer pour perfusion, CARBOPLATINE TEVA 10 mg/ml, solution pour perfusion, MELPHALAN, VINCRISTINE TEVA 1 mg/ml, solution injectable, ALKERAN 50 mg poudre et solvant pour solution pour perfusion Melphalan

    The George Institute

    Retinoblastoma

    phase 2 small molecule active

    1 trial

  13. ETOPOSIDE, YTB323, CYTARABINE, CYCLOPHOSPHAMIDE MONOHYDRATE, BENDAMUSTINE HYDROCHLORIDE, FLUDARABINE PHOSPHATE, IBRUTINIB, TOCILIZUMAB

    Novartis Pharmaceuticals

    High-Risk large B-Cell lymphoma, Chronic lymphocytic leukemia/Small lymphocytic lymphoma, Diffuse large B-Cell lymphoma, Acute lymphoblastic leukemia

    phase 2 small molecule active

    1 trial

  14. EVP-6124

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 small molecule terminated

    1 trial

  15. EXEMESTANE, ANASTROZOLE, LETROZOLE

    Ningbo Cancer Hospital

    Post-menopausal women with localized luminal A breast cancer and considered at low risk of metastatic relapse

    phase 2 small molecule active

    1 trial

  16. EXEMESTANE, ANASTROZOLE, LETROZOLE, TAMOXIFEN

    Ningbo Cancer Hospital

    Postmenopausal patients with small (pT1a-b pN0) hormone receptor positive (HR⁺) and HER2 negative (HER2⁻) early breast cancer with a Luminal A phenotype and at low risk of recurrence.

    phase 2 small molecule active

    1 trial

  17. EXENATIDE

    Disc Medicine

    Gestational diabetes

    phase 2 small molecule active

    1 trial

  18. EXENATIDE

    Disc Medicine

    paragangliomas

    phase 2 small molecule active

    1 trial

  19. EXENATIDE , VERAPAMIL

    Disc Medicine

    type 1 diabetes mellitus

    phase 2 small molecule active

    1 trial

  20. EYU688

    Novartis Pharmaceuticals

    Dengue

    phase 2 small molecule active

    1 trial

  21. Early recognition of progressive lung fibrosis in systemic rheumatic diseases: a characterization of the pulmonary environment through extracellular vesicles, advanced and functional imaging

    Fondazione Telethon ETS

    Patients with connective tissue diseases at high risk of interstial lung disease

    phase 2 other active

    1 trial

  22. Eat Well Live Well Nutrition Program

    Grace Therapeutics

    Diabetes or Diabetes Prevention

    phase 2 other completed

    1 trial

  23. EcoNail™ (econazole 5%/SEPA® 18% nail lacquer)

    ABEONA THERAPEUTICS INC.

    Onychomycosis

    phase 2 small molecule completed

    1 trial

  24. Eculizumab

    Biocryst

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    phase 2 small molecule terminated

    1 trial

  25. Eculizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Kidney Transplantation

    phase 2 small molecule active

    1 trial

  26. Edaravone Dexborneol

    The First People's Hospital of Lianyungang

    Stroke, Ischemic

    phase 2 small molecule active

    1 trial

  27. Efavaleukin alfa

    Amgen

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial

  28. Efbemalenograstim alfa Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary/Secondary Prevention

    phase 2 small molecule active

    1 trial

  29. Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer Patients

    The George Institute

    Metastatic pancreatic adenocarcinoma

    phase 2 other active

    1 trial

  30. Efgartigimod, ARGX-113

    argenx

    Chronic Inflammatory Demyelinating Polyneuropathy

    phase 2 small molecule active

    1 trial

  31. Efinopegdutide

    Merck KGaA, Darmstadt, Germany

    Non-alcoholic Fatty Liver Disease

    phase 2 small molecule completed

    1 trial

  32. Efinopegdutide 20 mg/mL

    Merck KGaA, Darmstadt, Germany

    Nonalcoholic Fatty Liver Disease

    phase 2 small molecule completed

    1 trial

  33. Either normal nicotine content cigarettes (15.8mg/g) or reduced nicotine content cigarettes (0.4mg/g)

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 other completed

    1 trial

  34. Ejiao compound

    The First People's Hospital of Lianyungang

    Postpartum Anemia

    phase 2 small molecule active

    1 trial

  35. Elacestrant

    Context Therapeutics

    Breast Cancer

    phase 2 small molecule terminated

    2 trials

  36. Eladocagene Exuparvovec

    PTC THERAPEUTICS, INC.

    AADC Deficiency

    phase 2 gene therapy active

    1 trial

  37. Elironrasib

    Revolution Medicines

    Non-Small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  38. Elliptical exercise

    United Therapeutics Europe Ltd

    Adult

    phase 2 other completed

    1 trial

  39. Elotuzumab

    Atrium Therapeutics

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  40. Elotuzumab, Selinexor, and Dexamethasone (ESd)

    Karyopharm Therapeutics Inc

    Relapsed Multiple Myeloma

    phase 2 small molecule terminated

    1 trial

  41. Elritercept

    Takeda

    Myelodysplastic Syndromes

    phase 2 small molecule active

    2 trials

  42. Elritercept

    Takeda

    Myelofibrosis

    phase 2 small molecule active

    1 trial

  43. Elsubrutinib

    AbbVie

    Systemic Lupus Erythematosus (SLE)

    phase 2 small molecule completed

    1 trial

  44. Eltrekibart

    Eli Lilly and Company

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  45. Eltrekibart, 0.9% sodium chloride

    Eli Lilly Co.

    Moderate to Severe Hidradenitis Suppurativa

    phase 2 small molecule active

    1 trial

  46. Eltrekibart, 0.9% sodium chloride, Mirikizumab, Mirikizumab, Placebo for LY3074828 SC Injection, 1mL Prefilled Syringe

    Eli Lilly Co.

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  47. Eltrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Thrombocytopenia Purpura

    phase 2 small molecule completed

    1 trial

  48. Eltrombopag

    Novartis Pharmaceuticals

    Aplastic Anemia

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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