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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

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  1. Divalproex Sodium (Depakote)

    BRIGHT MINDS BIOSCIENCES INC.

    Mood Disorders

    phase 2 small molecule completed

    1 trial

  2. Docetaxel

    Karyopharm Therapeutics Inc

    Recurrent Squamous Cell Lung Carcinoma

    phase 2 small molecule terminated

    1 trial

  3. Docetaxel

    Hospital Authority, Hong Kong

    Non Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial

  4. Docetaxel

    BRIGHT MINDS BIOSCIENCES INC.

    Prostatic Neoplasms

    phase 2 small molecule completed

    1 trial

  5. Docetaxel

    Takeda

    Non-small Cell Lung Cancer

    phase 2 small molecule terminated

    1 trial

  6. Docetaxel

    Merck KGaA, Darmstadt, Germany

    Castration-Resistant Prostatic Cancer

    phase 2 small molecule active

    1 trial

  7. Docetaxel + Sunitinib

    Samsung Bioepis NL B.V.

    Advanced Gastric Cancer

    phase 2 small molecule completed

    1 trial

  8. Docetaxel, Reolysin and Prednisone

    ONCOLYTICS BIOTECH INC

    Prostate Cancer

    phase 2 small molecule completed

    1 trial

  9. Dociparstat sodium

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia

    phase 2 small molecule completed

    1 trial

  10. Domvanalimab

    Arcus Biosciences

    Advanced Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  11. Domvanalimab

    Arcus Biosciences

    Gastrointestinal Tract Malignancies

    phase 2 small molecule active

    1 trial

  12. Domvanalimab

    Arcus Biosciences

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    2 trials

  13. Domvanalimab

    Arcus Biosciences

    Head and Neck Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  14. Donafenib + Envafolimab

    Anhui Provincial Hospital

    Hepatocellular Carcinoma

    phase 2 small molecule active

    1 trial

  15. Donanemab

    Eli Lilly and Company

    Cognitive Dysfunction

    phase 2 small molecule active

    1 trial

  16. Donepezil Hydrochloride

    Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    Radiation Injuries

    phase 2 small molecule active

    1 trial

  17. Dopacis 90 MBq/ml oplossing voor injectie

    CERO THERAPEUTICS HOLDINGS, INC.

    patients with newly discovered brain metastases (non-small cell lung cancer, breast cancer or melanoma) measuring more than 5 mm and explored on MRI

    phase 2 small molecule active

    1 trial

  18. Doravirine

    Merck KGaA, Darmstadt, Germany

    Human Immunodeficiency Virus (HIV) Infection

    phase 2 small molecule active

    1 trial

  19. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Glioblastoma

    phase 2 small molecule terminated

    1 trial

  20. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Endometrial Cancer Recurrent

    phase 2 small molecule terminated

    1 trial

  21. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Glioma

    phase 2 small molecule terminated

    1 trial

  22. Dose 1 of BMN 331

    BioMarin Pharmaceutical Australia Pty Ltd

    Hereditary Angioedema

    phase 2 gene therapy active

    1 trial

  23. Dose A KER-012

    Keros Therapeutics

    Pulmonary Arterial Hypertension

    phase 2 mab completed

    1 trial

  24. Dose Escalation Doublet: Combination of NKTR-214 + nivolumab

    Nektar Therapeutics UK Limited

    Melanoma

    phase 2 small molecule completed

    1 trial

  25. Dose-attenuated IST and Hetrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Sever Aplastic Anaemia

    phase 2 small molecule active

    1 trial

  26. Dostarlimab

    Hospital Authority, Hong Kong

    Female

    phase 2 small molecule active

    1 trial

  27. Dostarlimab

    LIXTE BIOTECHNOLOGY HOLDINGS, INC.

    Ovarian Clear Cell Carcinoma

    phase 2 small molecule active

    1 trial

  28. Double Trouble in Recovery

    BRIGHT MINDS BIOSCIENCES INC.

    Dual Diagnosis

    phase 2 other completed

    1 trial

  29. Double-Blind 0.2mg CBP-307

    S.L

    Moderate to Severe Ulcerative Colitis

    phase 2 small molecule completed

    1 trial

  30. Double-blind investigational anti-arrhythmic

    Wyeth is now a wholly owned subsidiary of Pfizer

    Arrhythmias

    phase 2 small molecule terminated

    1 trial

  31. Dovato 50 mg/300 mg film-coated tablets, Descovy 200 mg/25 mg film-coated tablets

    ViiV Healthcare Pty Ltd

    HIV Infections

    phase 2 small molecule active

    1 trial

  32. Doxazosin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    2 trials

  33. Doxazosin 4 mg daily plus Celecoxib 200 mg every day (QD)

    Hospital Authority, Hong Kong

    Benign Prostatic Hyperplasia

    phase 2 small molecule completed

    1 trial

  34. Doxazosin 4mg/day

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 2 small molecule completed

    1 trial

  35. Doxazosin Mesylate, Extended Release

    United Therapeutics Europe Ltd

    Stress Disorders, Post-Traumatic

    phase 2 small molecule active

    1 trial

  36. Doxazosin extended release

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine or Cocaine Dependence

    phase 2 small molecule completed

    1 trial

  37. Doxorubicin Hydrochloride

    Children's Hospital of Fudan University

    Childhood Renal Cell Carcinoma

    phase 2 small molecule completed

    1 trial

  38. Doxorubicin liposome

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule active

    1 trial

  39. Doxycycline

    Hospital Authority, Hong Kong

    Tuberculosis, Meningeal

    phase 2 small molecule active

    1 trial

  40. Doxycycline

    United Therapeutics Europe Ltd

    Advanced Malignant Neoplasm

    phase 2 small molecule completed

    1 trial

  41. Doxycycline EG 200 mg Tabletten

    The George Institute

    Bacterial sexually transmittable diseases (chlamydia, gonorrhea, syphilis)

    phase 2 small molecule active

    1 trial

  42. Dragon Boat Training

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 other active

    1 trial

  43. Dream01, IMATINIB

    Pari Pharma GmbH

    SCD severe patients

    phase 2 small molecule active

    1 trial

  44. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use Disorder

    phase 2 small molecule active

    1 trial

  45. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Dependence

    phase 2 small molecule terminated

    2 trials

  46. Dronabinol 120mg/day

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Smoking

    phase 2 small molecule completed

    1 trial

  47. Dronabinol 30mg/day

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Abuse

    phase 2 small molecule completed

    1 trial

  48. Dronabinol MDI

    Nektar Therapeutics UK Limited

    Migraine With Aura

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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