Metabolic & obesity · Phase II

Top sponsors

• Takeda 13 programs
• IONIS PHARMACEUTICALS 10 programs
• Oramed Pharmaceuticals 10 programs
• Regeneron UK 10 programs
• United Therapeutics Europe 7 programs
• Anaxis Pharma 6 programs
• NovoThirteen 6 programs
• Vertex Pharmaceuticals (Australia) 6 programs
• vTv Therapeutics 6 programs
• Alnylam Netherlands 5 programs
• LEXICON PHARMACEUTICALS 5 programs
• Rhythm Pharmaceuticals Netherlands 5 programs

1. JMKX000623

   Jemincare

   Diabetic Peripheral Neuropathic Pain

   phase 2 · small molecule · active

   1 trial →

2. Jiangtang Tiaozhi recipe

   Xiyuan Hospital of China Academy of Chinese Medical Sciences

   Type2 Diabetes

   phase 2 · small molecule · active

   1 trial →

3. K-001-201

   The George Institute

   Noncirrhotic Nonalcoholic Steatohepatitis (NASH) with Liver Fibrosis

   phase 2 · small molecule · active

   1 trial →

4. KAI-7535

   Kailera Therapeutics

   Obesity

   phase 2 · small molecule · active

   2 trials →

5. KVD001 Injection

   Kalvista Pharmaceuticals (Ireland) Limited

   Diabetic Macular Edema

   phase 2 · small molecule · completed

   2 trials →

6. LB54640

   Rhythm Pharmaceuticals Netherlands B.V.

   Hypothalamic Obesity

   phase 2 · small molecule · completed

   1 trial →

7. LGD-6972-5 mg

   LIGAND PHARMACEUTICALS INC

   Type 2 Diabetes Mellitus

   phase 2 · small molecule · completed

   1 trial →

8. LIK066

   Novartis Pharmaceuticals

   Obese Patients With Non-alcoholic Steatohepatitis (NASH)

   phase 2 · small molecule · completed

   1 trial →

9. LX4211 Low Dose

   LEXICON PHARMACEUTICALS, INC.

   Type 2 Diabetes Mellitus

   phase 2 · small molecule · completed

   1 trial →

10. LX9211

    LEXICON PHARMACEUTICALS, INC.

    Diabetic Peripheral Neuropathy

    phase 2 · small molecule · completed

    1 trial →

11. Ladarixin, Placebo to match Ladarixin

    Dompe' Farmaceutici S.p.A.

    Recent onset Type 1 Diabetes

    phase 2 · small molecule · active

    1 trial →

12. MB07803

    LIGAND PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

13. MK-6024-017

    Merck Sharp and Dohme

    Metabolic Dysfunction-Associated Steatohepatitis

    phase 2 · small molecule · active

    1 trial →

14. MLN1202 Placebo

    Takeda

    Diabetic Nephropathy

    phase 2 · small molecule · terminated

    1 trial →

15. MSC

    Shandong University

    Type 2 Diabetes

    phase 2 · mab · active

    1 trial →

16. MSC and PRP

    Hospital Authority, Hong Kong

    Type 1 Diabetes Mellitus

    phase 2 · mab · active

    1 trial →

17. Matching Placebo

    Cyclerion Therapeutics

    Diabetes Mellitus, Type 2

    phase 2 · small molecule · completed

    1 trial →

18. MenSCs transplantation

    The First People's Hospital of Lianyungang

    Type 1 Diabetes Mellitus

    phase 2 · mab · active

    1 trial →

19. Miricorilant

    CORCEPT THERAPEUTICS INC

    Nonalcoholic Steatohepatitis (NASH)

    phase 2 · small molecule · active

    3 trials →

20. Miricorilant (Cohort A)

    CORCEPT THERAPEUTICS INC

    Nonalcoholic Steatohepatitis (NASH)

    phase 2 · small molecule · active

    1 trial →

21. Motivational Interviewing

    Cardiff Oncology

    Diabetes Mellitus

    phase 2 · other · terminated

    1 trial →

22. NAT-19/GPX

    Dr. Falk Pharma GmbH

    Idiopathic or Diabetic Gastroparesis

    phase 2 · small molecule · active

    1 trial →

23. NN9388-7700

    NovoThirteen

    Chronic Kidney Disease, Type 2 diabetes

    phase 2 · small molecule · active

    1 trial →

24. NN9388-7864

    NovoThirteen

    Type 2 diabetes and painful diabetic peripheral neuropathy

    phase 2 · small molecule · active

    1 trial →

25. NN9490-7678

    NovoThirteen

    Type 2 Diabetes

    phase 2 · small molecule · active

    1 trial →

26. NN9500-4656

    NovoThirteen

    Non-alcoholic steatohepatitis (NASH)

    phase 2 · small molecule · active

    1 trial →

27. NN9541-7841

    NovoThirteen

    Chronic Kidney Disease, with or without Type 2 diabetes, Obesity

    phase 2 · small molecule · active

    1 trial →

28. NN9662-8160

    NovoThirteen

    type 2 diabetes

    phase 2 · small molecule · active

    1 trial →

29. Naltrexone hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Obesity

    phase 2 · small molecule · active

    1 trial →

30. Namodenoson

    Can-Fite BioPharma

    NASH - Nonalcoholic Steatohepatitis

    phase 2 · small molecule · active

    1 trial →

31. Namodenoson, Matching placebo for namodenoson

    Can-Fite BioPharma

    Non-Alcoholic Steatohepatitis (NASH) with F1-3 fibrosis

    phase 2 · small molecule · active

    1 trial →

32. ORMD 0801

    ORAMED PHARMACEUTICALS INC.

    Brittle Type I Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

33. ORMD-0801

    ORAMED PHARMACEUTICALS INC.

    Diabetes Type 2

    phase 2 · small molecule · completed

    1 trial →

34. ORMD-0801 (Insulin) capsule 8 mg BD

    ORAMED PHARMACEUTICALS INC.

    Diabetes Mellitus, Type 2

    phase 2 · small molecule · completed

    1 trial →

35. ORMD-0801 Capsules

    ORAMED PHARMACEUTICALS INC.

    Diabetes Mellitus Type 1

    phase 2 · mab · completed

    1 trial →

36. ORMD-0801 Dose # 1

    ORAMED PHARMACEUTICALS INC.

    Diabetes Mellitus Type 2

    phase 2 · small molecule · completed

    1 trial →

37. ORMD-0801 QD

    ORAMED PHARMACEUTICALS INC.

    Nonalcoholic Steatohepatitis (NASH)

    phase 2 · small molecule · completed

    1 trial →

38. ORMD-0801 Treatment A

    ORAMED PHARMACEUTICALS INC.

    Type 1 Diabetes

    phase 2 · small molecule · completed

    1 trial →

39. ORMD-0801 capsules- 2x8mg

    ORAMED PHARMACEUTICALS INC.

    Type 1 Diabetes

    phase 2 · small molecule · completed

    1 trial →

40. Olatorepatide

    Regeneron UK Limited

    Overweight or Obesity

    phase 2 · small molecule · active

    1 trial →

41. Omnitram Oral Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetic Neuropathies

    phase 2 · small molecule · completed

    1 trial →

42. Oral Insulin

    ORAMED PHARMACEUTICALS INC.

    Non-Alcoholic Steatohepatitis (NASH)

    phase 2 · mab · completed

    1 trial →

43. Oshadi Icp

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetes Mellitus, Insulin-Dependent, 1

    phase 2 · small molecule · completed

    1 trial →

44. P120142

    Pari Pharma GmbH

    Patient with newly diagnosed (≤ 3 months) type 1 diabetes stage 3

    phase 2 · small molecule · active

    1 trial →

45. PEX168 or placebo

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Type 2 Diabetes

    phase 2 · small molecule · completed

    1 trial →

46. PRAM9

    Xeris Biopharma Holdings

    Diabetes Mellitus, Type 1

    phase 2 · small molecule · completed

    1 trial →

47. Part A: RM-718 or placebo (matched to specific RM-718 dose cohort)

    Rhythm Pharmaceuticals Netherlands B.V.

    Hypothalamic Obesity

    phase 2 · small molecule · active

    1 trial →

48. Pear

    NORTHWEST BIOTHERAPEUTICS INC

    Metabolic Syndrome

    phase 2 · other · completed

    1 trial →

Frequently asked questions