Metabolic & obesity · Phase II

Top sponsors

• Takeda 13 programs
• IONIS PHARMACEUTICALS 10 programs
• Oramed Pharmaceuticals 10 programs
• Regeneron UK 10 programs
• United Therapeutics Europe 7 programs
• Anaxis Pharma 6 programs
• NovoThirteen 6 programs
• Vertex Pharmaceuticals (Australia) 6 programs
• vTv Therapeutics 6 programs
• Alnylam Netherlands 5 programs
• LEXICON PHARMACEUTICALS 5 programs
• Rhythm Pharmaceuticals Netherlands 5 programs

1. Canakinumab 150 mg

   Novartis Pharmaceuticals

   Type 2 Diabetes Mellitus

   phase 2 · small molecule · completed

   1 trial →

2. Cohort A: ORMD-0801

   ORAMED PHARMACEUTICALS INC.

   T2DM (Type 2 Diabetes Mellitus)

   phase 2 · small molecule · completed

   1 trial →

3. D7260C00001

   AstraZeneca AB

   Participants living with Obesity or Overweight with at least 1 comorbidity

   phase 2 · small molecule · active

   1 trial →

4. D7261C00001

   AstraZeneca AB

   Type 2 Diabetes Mellitus

   phase 2 · small molecule · active

   1 trial →

5. D8460C00004

   AstraZeneca AB

   Investigating obesity or overweight condition correlated to many co-morbidities

   phase 2 · small molecule · active

   1 trial →

6. DA-302168S

   Chendu DIAO Pharmaceutical Group CO., LTD.

   Overweight and Obesity

   phase 2 · small molecule · active

   1 trial →

7. DCCR (diazoxide choline) extended-release tablets

   SOLENO THERAPEUTICS INC

   SH2B1 Deficiency Obesity

   phase 2 · small molecule · active

   1 trial →

8. DIABECELL(R)

   Otsuka Beijing Research Institute

   Type 1 Diabetes

   phase 2 · other · completed

   1 trial →

9. DM199

   DiaMedica Therapeutics

   Diabetes Type 2

   phase 2 · small molecule · completed

   1 trial →

10. DRI17476

    Sanofi-aventis Healthcare Pty Ltd

    Type 1 diabetes mellitus

    phase 2 · other · active

    1 trial →

11. Diamyd

    Wuhan Createrna Science and Technology Co., Ltd

    Latent Autoimmune Diabetes in Adults (LADA)

    phase 2 · small molecule · active

    1 trial →

12. EP-005

    Lacuna Pharma Pty Ltd

    Obesity

    phase 2 · small molecule · active

    1 trial →

13. EXENATIDE

    Disc Medicine

    Gestational diabetes

    phase 2 · small molecule · active

    1 trial →

14. EXENATIDE , VERAPAMIL

    Disc Medicine

    type 1 diabetes mellitus

    phase 2 · small molecule · active

    1 trial →

15. Eat Well Live Well Nutrition Program

    Grace Therapeutics

    Diabetes or Diabetes Prevention

    phase 2 · other · completed

    1 trial →

16. Evogliptin

    Samsung Bioepis NL B.V.

    Type2 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

17. External Chinese medicine

    Universal Integrated

    Diabetic Foot

    phase 2 · small molecule · active

    1 trial →

18. Fasiglifam

    Takeda

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · terminated

    2 trials →

19. G-Pen Mini™ (glucagon injection)

    Xeris Biopharma Holdings

    Diabetes Mellitus, Type 1

    phase 2 · small molecule · completed

    2 trials →

20. GIP/GLP-1a

    United Therapeutics Europe Ltd

    Non-Alcoholic Fatty Liver Disease

    phase 2 · small molecule · active

    1 trial →

21. GK1-399 (formerly TTP399)

    vTv Therapeutics

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

22. GSBR-1290

    Structure Therapeutics

    Overweight or Obesity

    phase 2 · small molecule · completed

    1 trial →

23. GSK2330672

    ELITE PHARMACEUTICALS INC /NV/

    Diabetes Mellitus, Type 2

    phase 2 · small molecule · completed

    1 trial →

24. GWP42004

    Jazz Pharmaceuticals Ireland Limited

    Diabetes Mellitus, Type 2

    phase 2 · small molecule · completed

    1 trial →

25. GZR102

    Gan & Lee Pharmaceuticals.

    Type 2 Diabetes Mellitus (T2DM)

    phase 2 · small molecule · active

    1 trial →

26. Grafalon 20 mg/ml koncentrát pro infuzní roztok

    The George Institute

    Type 1 diabetes

    phase 2 · small molecule · active

    1 trial →

27. High Dose SAB-142

    SAB Biotherapeutics

    Type 1 Diabetes

    phase 2 · small molecule · active

    1 trial →

28. Humalog

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus, Type 2

    phase 2 · small molecule · completed

    1 trial →

29. Humalog

    HALOZYME THERAPEUTICS, INC.

    Type 1 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

30. I8F-MC-GPIG

    Eli Lilly Co.

    Chronic Kidney Disease, CKD, Obesity, Overweight, T2D, Type 2 Diabetes

    phase 2 · small molecule · active

    1 trial →

31. ISIS 113715

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · completed

    5 trials →

32. ISIS-APOCIIIRX

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes

    phase 2 · small molecule · terminated

    1 trial →

33. ISIS-FGFR4RX

    IONIS PHARMACEUTICALS INC

    Obesity

    phase 2 · small molecule · completed

    1 trial →

34. ISIS-GCCRRx

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

35. ISIS-GCGRRx

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes

    phase 2 · small molecule · completed

    1 trial →

36. ISIS-GCGRRx - Dose Level 1

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

37. ISIS-GCGRRx- Dose Level 1

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes

    phase 2 · small molecule · completed

    1 trial →

38. ISIS-PTP1BRx

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 2 · small molecule · completed

    1 trial →

39. IW-1973

    Akebia Europe Limited

    Type 2 Diabetes Mellitus With Diabetic Nephropathy

    phase 2 · small molecule · completed

    1 trial →

40. IW-1973

    Cyclerion Therapeutics

    Diabetes Mellitus, Type 2

    phase 2 · small molecule · completed

    1 trial →

41. IW-9179

    IRONWOOD PHARMACEUTICALS INC

    Diabetic Gastroparesis

    phase 2 · small molecule · completed

    1 trial →

42. Insulin lispro

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus, Type 1

    phase 2 · small molecule · completed

    2 trials →

43. Insulin lispro

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus, Type II

    phase 2 · small molecule · completed

    1 trial →

44. Intravitreal Aflibercept Injection

    Regeneron UK Limited

    Diabetic Macular Edema

    phase 2 · small molecule · completed

    1 trial →

45. Investigational new drug company code: BGS649

    Mereo BioPharma Group plc

    Obese Hypogonadotropic Hypogonadism

    phase 2 · small molecule · terminated

    1 trial →

46. Islet transplantation with Tegoprubart (AT-1501) immunosupression-based therapy

    Eledon Pharmaceuticals

    Type 1 Diabetes Mellitus

    phase 2 · small molecule · active

    1 trial →

47. J1I-MC-GZBU

    Eli Lilly Co.

    Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

    phase 2 · small molecule · active

    1 trial →

48. J1R-MC-GZFD

    Eli Lilly Co.

    Type 2 Diabetes

    phase 2 · small molecule · active

    1 trial →

Frequently asked questions