Neurology & CNS · Phase II

Top sponsors

• BRIGHT MINDS BIOSCIENCES 13 programs
• United Therapeutics Europe 12 programs
• Chinese Academy of 11 programs
• Teva Pharma 11 programs
• Jazz Pharmaceuticals Ireland 10 programs
• Acadia Pharmaceuticals 9 programs
• HOFFMANN-LA ROCHE 9 programs
• George Institute for 8 programs
• SUPERNUS PHARMACEUTICALS 8 programs
• Cognition Therapeutics 7 programs
• Takeda 7 programs
• Anaxis Pharma 6 programs

1. TAK-653

   Takeda

   Treatment-Resistant Depression

   phase 2 · small molecule · terminated

   1 trial →

2. TAK-935

   Takeda

   Epilepsy

   phase 2 · small molecule · completed

   2 trials →

3. TMP-18122023-58

   Lacuna Pharma Pty Ltd

   Adults with ADHD and moderate to severe depression

   phase 2 · small molecule · active

   1 trial →

4. TNX-601 ER

   Tonix Pharmaceuticals Holding

   Depression

   phase 2 · small molecule · completed

   1 trial →

5. TPM XR

   SUPERNUS PHARMACEUTICALS, INC.

   Epilepsy

   phase 2 · small molecule · completed

   1 trial →

6. Talampanel

   Teva Pharma GmbH

   Epilepsy

   phase 2 · small molecule · completed

   1 trial →

7. TolDec

   The George Institute

   Multiple sclerosis

   phase 2 · small molecule · active

   1 trial →

8. UB-311

   United Therapeutics Europe Ltd

   Alzheimer's Disease

   phase 2 · mab · terminated

   3 trials →

9. Ublituximab

   TG THERAPEUTICS, INC.

   multiple sclerosis

   phase 2 · small molecule · active

   1 trial →

10. Ublituximab

    TG THERAPEUTICS, INC.

    Relapsing Remitting Multiple Sclerosis

    phase 2 · mab · completed

    1 trial →

11. VX-765

    Vertex Pharmaceuticals (Australia) Pty.

    Partial Epilepsy

    phase 2 · small molecule · completed

    1 trial →

12. VX-765 Part A

    Vertex Pharmaceuticals (Australia) Pty.

    Epilepsy

    phase 2 · small molecule · terminated

    1 trial →

13. VY7523

    Voyager Therapeutics

    Alzheimer's Disease (AD)

    phase 2 · small molecule · active

    1 trial →

14. Venlafaxine

    BRIGHT MINDS BIOSCIENCES INC.

    Depression

    phase 2 · small molecule · completed

    1 trial →

15. Vitamin D3

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 · other · completed

    1 trial →

16. WA39085

    Hoffmann-La Roche

    Relapsing-Remitting Multiple Sclerosis (RRMS)

    phase 2 · small molecule · active

    1 trial →

17. Wei Li Bai capsules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Alzheimer Disease

    phase 2 · small molecule · terminated

    1 trial →

18. XPF-008-201

    Xenon Pharmaceuticals

    Adult focal (partial onset) epilepsy

    phase 2 · small molecule · active

    1 trial →

19. ZB012-02-002

    Zenas BioPharma

    RELAPSING MULTIPLE SCLEROSIS

    phase 2 · small molecule · active

    1 trial →

20. [123I] 5-IA

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 · small molecule · completed

    1 trial →

21. [123I]B-CIT

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 · small molecule · completed

    1 trial →

22. [123I]β-CIT

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 · small molecule · active

    1 trial →

23. [18F]PI-2620

    The George Institute

    Down Syndrome., Alzheimer´s Disease.

    phase 2 · small molecule · active

    1 trial →

24. [18F]PI-2620

    The George Institute

    Down Syndrome, Alzheimer disease

    phase 2 · small molecule · active

    1 trial →

25. [18F]PI-2620

    The George Institute

    Progressive supranuclear palsy, Parkinson's disease

    phase 2 · small molecule · active

    1 trial →

26. armodafinil

    Teva Pharma GmbH

    Schizophrenia

    phase 2 · small molecule · completed

    2 trials →

27. ataluren

    PTC THERAPEUTICS, INC.

    Epilepsy

    phase 2 · small molecule · completed

    1 trial →

28. fetal nigral transplantation

    Ultragenyx UK Limited

    Parkinson Disease

    phase 2 · other · completed

    1 trial →

29. glatiramer acetate 20 mg

    Teva Pharma GmbH

    Relapse-Remitting Multiple Sclerosis

    phase 2 · small molecule · completed

    1 trial →

30. glatiramer acetate 20 mg

    Teva Pharma GmbH

    Relapsing Remitting Multiple Sclerosis

    phase 2 · small molecule · completed

    1 trial →

31. glatiramer acetate with minocycline

    Teva Pharma GmbH

    Relapse Remitting Multiple Sclerosis

    phase 2 · small molecule · completed

    1 trial →

32. laquinimod 0.3

    Teva Pharma GmbH

    Relapsing Remitting Multiple Sclerosis

    phase 2 · small molecule · completed

    1 trial →

33. levodopa

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 · small molecule · completed

    1 trial →

34. methylprednisolone

    Teva Pharma GmbH

    Multiple Sclerosis (MS)

    phase 2 · small molecule · terminated

    1 trial →

35. mutual support group

    Hong Kong Baptist University

    Schizophrenia

    phase 2 · other · completed

    1 trial →

36. pallidotomy

    Ultragenyx UK Limited

    Parkinson Disease

    phase 2 · other · completed

    1 trial →

37. pioglitazone

    Takeda

    Alzheimer Disease

    phase 2 · small molecule · completed

    1 trial →

38. sabirnetug

    Acumen Pharmaceuticals

    Alzheimer Disease

    phase 2 · small molecule · active

    1 trial →

39. sarcosine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenia

    phase 2 · small molecule · completed

    1 trial →

40. sodium oxybate

    Jazz Pharmaceuticals Ireland Limited

    Parkinson Disease

    phase 2 · small molecule · completed

    1 trial →

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