Neurology & CNS · Phase II

Top sponsors

• BRIGHT MINDS BIOSCIENCES 13 programs
• United Therapeutics Europe 12 programs
• Chinese Academy of 11 programs
• Teva Pharma 11 programs
• Jazz Pharmaceuticals Ireland 10 programs
• Acadia Pharmaceuticals 9 programs
• HOFFMANN-LA ROCHE 9 programs
• George Institute for 8 programs
• SUPERNUS PHARMACEUTICALS 8 programs
• Cognition Therapeutics 7 programs
• Takeda 7 programs
• Anaxis Pharma 6 programs

1. CBD-ESPRIT

   The George Institute

   Remitted early phase schizophrenia

   phase 2 · small molecule · active

   1 trial →

2. CERE-110: Adeno-Associated Virus injection Surgery

   SANGAMO THERAPEUTICS, INC

   Alzheimer's Disease

   phase 2 · small molecule · completed

   1 trial →

3. CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN])

   SANGAMO THERAPEUTICS, INC

   Idiopathic Parkinson's Disease

   phase 2 · small molecule · completed

   1 trial →

4. CERE-120: Adeno-Associated Virus Delivery of Neurturin

   SANGAMO THERAPEUTICS, INC

   Idiopathic Parkinson's Disease

   phase 2 · mab · completed

   1 trial →

5. CET/PT

   BRIGHT MINDS BIOSCIENCES INC.

   Schizophrenia

   phase 2 · other · completed

   1 trial →

6. CGXV813B12201

   Novartis Pharmaceuticals

   Schizophrenia

   phase 2 · small molecule · active

   1 trial →

7. CN008-0003

   Bristol-Myers Squibb Australia Pty Ltd

   Early Alzheimer’s Disease

   phase 2 · small molecule · active

   1 trial →

8. CN45320

   Hoffmann-La Roche

   Multiple Sclerosis (MS)

   phase 2 · small molecule · active

   1 trial →

9. CNSA-001

   PTC THERAPEUTICS, INC.

   Gastroparesis

   phase 2 · small molecule · completed

   1 trial →

10. CO40778

    Hoffmann-La Roche

    Pediatric Solid tumors and primary central nervous system (CNS) tumors

    phase 2 · small molecule · active

    1 trial →

11. CT1812

    COGNITION THERAPEUTICS INC

    Alzheimer Disease

    phase 2 · small molecule · completed

    3 trials →

12. CT1812

    COGNITION THERAPEUTICS INC

    Mild to Moderate Alzheimer's Disease

    phase 2 · small molecule · completed

    1 trial →

13. CT1812

    COGNITION THERAPEUTICS INC

    Alzheimer's Disease

    phase 2 · small molecule · completed

    1 trial →

14. CT1812

    COGNITION THERAPEUTICS INC

    Early Alzheimer's Disease

    phase 2 · small molecule · active

    1 trial →

15. CVHB937A12201

    Novartis Pharmaceuticals

    Alzheimer’s disease

    phase 2 · small molecule · active

    1 trial →

16. CX-8998

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 2 · small molecule · completed

    1 trial →

17. CX-8998

    Jazz Pharmaceuticals Ireland Limited

    Parkinson's Disease

    phase 2 · small molecule · terminated

    1 trial →

18. CYTB323N12101

    Novartis Pharmaceuticals

    Relapsing Multiple Sclerosis

    phase 2 · small molecule · active

    1 trial →

19. CYTB323R12101

    Novartis Pharmaceuticals

    Non-active Progressive Multiple Sclerosis (PMS)

    phase 2 · small molecule · active

    1 trial →

20. Clonazepam

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 2 · small molecule · completed

    1 trial →

21. D20-P012

    Pari Pharma GmbH

    Alzheimer Disease

    phase 2 · small molecule · active

    1 trial →

22. D24-P003

    Pari Pharma GmbH

    Treatment-resistant depression

    phase 2 · small molecule · active

    1 trial →

23. DAAOI-P

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Parkinson's Disease With Dementia

    phase 2 · small molecule · completed

    1 trial →

24. DMTs + taurine

    The First People's Hospital of Lianyungang

    Multiple Sclerosis (MS) Relapsing Remitting

    phase 2 · small molecule · active

    1 trial →

25. DR220204

    Tour Hekla

    psychiatry

    phase 2 · small molecule · active

    1 trial →

26. Dexmedetomidine

    COGNITION THERAPEUTICS INC

    Alzheimer Disease

    phase 2 · small molecule · completed

    1 trial →

27. Diazepam Buccal Film

    Aquestive Therapeutics

    Epilepsy

    phase 2 · small molecule · completed

    2 trials →

28. Diazepam Buccal Film 12.5 mg

    Aquestive Therapeutics

    Epilepsy

    phase 2 · small molecule · completed

    1 trial →

29. E2007-G000-236

    Eisai Co.,

    Childhood Epilepsy

    phase 2 · small molecule · active

    1 trial →

30. EBVALLO

    Pierre Fabre Medicament

    EBV+ primary imunodeficiency lymphoproliferative disease (LPD), EBV+ post-transplant LPD where standard first line therapy (rituximab or chemotherapy) is inappropriate, including CD20-negative disease, EBV+ sarcomas, including leiomyosarcoma, or smooth muscle tumors, EBV+ associated post-transplant LPD involving the central nervous system (EBV+ CNS PTLD)

    phase 2 · small molecule · active

    1 trial →

31. Evaluation of the safety and efficacy of Cont... for Parkinson's disease

    Lacuna Pharma Pty Ltd

    Parkinson's disease

    phase 2 · other · active

    1 trial →

32. Everolimus

    BRIGHT MINDS BIOSCIENCES INC.

    Epilepsy

    phase 2 · small molecule · active

    1 trial →

33. ExPlas

    Wuhan Createrna Science and Technology Co., Ltd

    Early symptomatic phase Alzheimer's disease

    phase 2 · small molecule · active

    1 trial →

34. Exercise Programme

    United Therapeutics Europe Ltd

    Parkinson's Disease

    phase 2 · other · completed

    1 trial →

35. Flortaucipir, Placebo to match LY3372689

    Eli Lilly Co.

    Alzheimer Disease

    phase 2 · small molecule · active

    1 trial →

36. Fluoxetine

    The First People's Hospital of Lianyungang

    Depression

    phase 2 · small molecule · active

    1 trial →

37. GH001-TRD-201

    Elan Pharma International

    Treatment-resistant depression (TRD)

    phase 2 · small molecule · active

    1 trial →

38. GN-002

    Sana Biotechnology

    Parkinson’s Disease

    phase 2 · small molecule · active

    1 trial →

39. GN43271

    Hoffmann-La Roche

    Relapsing Multiple Sclerosis

    phase 2 · other · active

    1 trial →

40. GSK4527226

    GlaxoSmithKline

    Alzheimer's Disease

    phase 2 · small molecule · active

    1 trial →

41. GWP42003-P

    Jazz Pharmaceuticals Ireland Limited

    Schizophrenia

    phase 2 · small molecule · terminated

    1 trial →

42. GWP42003-P 5 mg/kg/day Dose

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 2 · small molecule · completed

    1 trial →

43. GWP42006

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 2 · small molecule · completed

    2 trials →

44. Glatiramer Acetate, N-Acetylcysteine

    Teva Pharma GmbH

    Relapse Remitting Multiple Sclerosis

    phase 2 · small molecule · completed

    1 trial →

45. GlyT-1 inhibitor-1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenia

    phase 2 · small molecule · completed

    1 trial →

46. Green Tea Polyphenols (EGCG/ECG)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Parkinson's Disease

    phase 2 · small molecule · completed

    1 trial →

47. I5T-MC-AACI

    Eli Lilly Co.

    Alzheimer Disease

    phase 2 · small molecule · active

    1 trial →

48. IC 2019-02

    The George Institute

    Primary Central Nervous System Lymphoma (PCNSL)

    phase 2 · other · active

    1 trial →

Frequently asked questions