Friday, July 10, 2026

Intelligence · Clinical pipeline

Autoimmune & immunology R&D Pipeline

Autoimmune, rheumatology, and immunology biologics in clinical development.

Programs 985

Quick answer

Autoimmune & immunology: NovaPharmaNews indexes 985 autoimmune & immunology clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. Autoimmune, rheumatology, and immunology biologics in clinical development.

Top sponsors

Pipeline programs

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  1. GRT-1C101

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 other active

    1 trial
  2. GRT-1C102

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 other active

    1 trial
  3. GS-0272

    Gilead Sciences Ireland UC

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial
  4. HN2301 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Systemic Lupus Erythematosus

    phase 1 small molecule active

    1 trial
  5. HN2302 Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Disease

    phase 1 small molecule active

    1 trial
  6. Human Umbilical Mesenchymal Stem Cells

    The First People's Hospital of Lianyungang

    Osteoarthritis, Knee

    phase 1 mab active

    1 trial
  7. Humanized TNFα monoclonal antibody

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial
  8. IASO206 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 mab active

    1 trial
  9. IM034-1000

    Bristol-Myers Squibb Australia Pty Ltd

    Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus, Systemic Lupus Erythematosus

    phase 1 other active

    1 trial
  10. IM060-0001

    Bristol-Myers Squibb Australia Pty Ltd

    Systemic Sclerosis, Idiopathic Inflammatory Myopathy, Rheumatoid Arthritis, Systemic Lupus Erythematosus

    phase 1 other active

    1 trial
  11. Ixazomib

    Takeda

    Lupus Nephritis

    phase 1 small molecule terminated

    1 trial
  12. JADE201

    Jade Biosciences

    Rhematoid Arthritis

    phase 1 small molecule active

    1 trial
  13. JANX011

    Janux Therapeutics

    Autoimmune

    phase 1 small molecule active

    1 trial
  14. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab terminated

    1 trial
  15. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 mab active

    1 trial
  16. LD and GC012F CAR-T Cell Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial
  17. LUCAR-DKS1 NK cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab active

    1 trial
  18. LUCAR-G79 T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab active

    1 trial
  19. LUCAR-G79D T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 mab active

    1 trial
  20. LVIVO-TaVec400 product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)

    phase 1 mab active

    1 trial
  21. LX3305

    LEXICON PHARMACEUTICALS, INC.

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial
  22. Linperlisib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 small molecule terminated

    1 trial
  23. M25-433

    AbbVie Deutschland GmbH & Co. KG

    Systemic Lupus Erythematosus, Sjogren's disease

    phase 1 other active

    1 trial
  24. MC-1-50

    Chongqing Precision Biotech Co., Ltd

    Systemic Lupus Erythematosus (SLE)

    phase 1 mab active

    1 trial
  25. MDGN-002

    Avalo Therapeutics

    Crohn Disease

    phase 1 small molecule terminated

    1 trial
  26. MESAL-02-25

    Lacuna Pharma Pty Ltd

    ulcerative colitis

    phase 1 other active

    1 trial
  27. MESAL-03-25

    Lacuna Pharma Pty Ltd

    ulcerative colitis

    phase 1 other active

    1 trial
  28. MESAL-19-24

    Lacuna Pharma Pty Ltd

    ulcerative colitis

    phase 1 other active

    1 trial
  29. MESAL-20-24

    Lacuna Pharma Pty Ltd

    ulcerative colitis

    phase 1 other active

    1 trial
  30. MK-1045-004

    Merck Sharp and Dohme

    Systemic lupus erythematosus, Rheumatoid arthritis

    phase 1 other active

    1 trial
  31. MK-2420 SAD Study

    Merck Sharp and Dohme

    Rheumatoid arthritis

    phase 1 other active

    1 trial
  32. Methotrexate

    Sana Biotechnology

    Chronic Plaque Psoriasis

    phase 1 small molecule active

    1 trial
  33. Methotrexate - Amneal

    Amneal Pharma Europe Ltd

    Psoriasis

    phase 1 small molecule active

    1 trial
  34. Methotrexate PK (in combination with Novobiocin) in RA patients

    Lacuna Pharma Pty Ltd

    Rheumatoid arthritis

    phase 1 other active

    1 trial
  35. Modified Gegen Qinlian Decoction

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Ulcerative Colitis

    phase 1 small molecule active

    1 trial
  36. No Intervention

    Takeda

    Rheumatoid Arthritis

    phase 1 other completed

    1 trial
  37. O3R-5671-CL-101

    Lacuna Pharma Pty Ltd

    Inflammatory bowel diseases and psoriasis.

    phase 1 other active

    1 trial
  38. Obecabtagene autoleucel (obe-cel)

    Autolus GmbH

    Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial
  39. PH-F8IL10INTRA-03/24

    Philogen S.p.A.

    Patients with Rheumatoid Arthritis (RA) who, despite treatment with stable doses (for at least 3 months) of disease-modifying antirheumatic drugs (DMARDs, conventional, biologic and/or targeted synthetic), present arthritis flare(s) suitable for intra-articular (IA) injection in a knee, shoulder, ankle, wrist or elbow.

    phase 1 other active

    1 trial
  40. PIPE-791

    Contineum Therapeutics

    Chronic Osteoarthritis Pain

    phase 1 small molecule completed

    1 trial
  41. PTOC1

    Chongqing Precision Biotech Co., Ltd

    Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial
  42. Phase 1 study on SAR443122 bioavailability and food effect in healthy adults

    Sanofi-aventis Healthcare Pty Ltd

    Colitis ulcerative

    phase 1 other active

    1 trial
  43. Placebo

    Nektar Therapeutics UK Limited

    Psoriasis

    phase 1 small molecule completed

    1 trial
  44. QT-019C

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    SLE - Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial
  45. R5459-1979-LN-2459

    Lacuna Pharma Pty Ltd

    Lupus Nephritis

    phase 1 other active

    1 trial
  46. RA-TL011-101

    Teva Pharma GmbH

    Rheumatoid Arthritis

    phase 1 mab completed

    1 trial
  47. REGN88

    Regeneron UK Limited

    Rheumatoid Arthritis

    phase 1 mab completed

    3 trials
  48. RO7507062

    Hoffmann-La Roche

    Systemic Lupus Erythematosus

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many autoimmune & immunology pipeline programs are tracked?

985 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.