Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Autoimmune & immunology R&D Pipeline

Autoimmune, rheumatology, and immunology biologics in clinical development.

Programs 985

Quick answer

Autoimmune & immunology: NovaPharmaNews indexes 985 autoimmune & immunology clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. Autoimmune, rheumatology, and immunology biologics in clinical development.

Top sponsors

Pipeline programs

Page 13 of 21

  1. ORKA-001, Placebo for ORKA-001

    Oruka Therapeutics

    Moderate-to-Severe Plaque Psoriasis

    phase 2 small molecule active

    1 trial

  2. ORKA-002

    Oruka Therapeutics

    Plaque Psoriasis

    phase 2 small molecule active

    1 trial

  3. Obecabtagene autoleucel

    Autolus GmbH

    Lupus Nephritis

    phase 2 mab active

    1 trial

  4. Obexelimab

    Zenas BioPharma

    Systemic Lupus Erythematosus

    phase 2 small molecule active

    1 trial

  5. Ocrelizumab

    Hoffmann-La Roche

    Rheumatoid Arthritis

    phase 2 small molecule terminated

    1 trial

  6. Oral Chinese Herbal Medicine of Clearing heat and Cooling blood therapy

    The First People's Hospital of Lianyungang

    Psoriasis

    phase 2 small molecule active

    1 trial

  7. P38 Inhibitor (4) 150mg

    Hoffmann-La Roche

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  8. PF-00547659

    Takeda

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  9. PF-00547659 SC injection

    Takeda

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  10. PF-04236921 SC injection

    Pfizer

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  11. PF-06650833

    Pfizer

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  12. PH-10 (0.001% Rose Bengal)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 small molecule completed

    1 trial

  13. PH-10 (0.002% Rose Bengal)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 small molecule completed

    1 trial

  14. PH-10 (rose bengal disodium 0.001%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Plaque Psoriasis

    phase 2 small molecule terminated

    1 trial

  15. PN-943

    Protagonist Therapeutics, Inc

    Ulcerative Colitis Chronic Moderate

    phase 2 small molecule completed

    1 trial

  16. PTG-100

    Protagonist Therapeutics, Inc

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial

  17. Placebo

    Takeda

    Ulcerative Colitis

    phase 2 small molecule completed

    1 trial

  18. Placebo

    Serono Europe Limited

    Systemic Lupus Erythematosus

    phase 2 small molecule terminated

    1 trial

  19. Placebo

    Theravance Biopharma Ireland Umited

    Crohn's Disease

    phase 2 small molecule terminated

    1 trial

  20. Placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  21. Placebo for MK-7240, tulisokibart

    Merck Sharp and Dohme

    Radiographic axial spondyloarthritis (as known as ankylosing spondylitis)

    phase 2 small molecule active

    1 trial

  22. Placebo oral capsule

    United Therapeutics Europe Ltd

    Osteoarthritis, Knee

    phase 2 small molecule completed

    1 trial

  23. Povetacicept

    Vertex Pharmaceuticals (Australia) Pty.

    Myasthenia Gravis, Generalized

    phase 2 small molecule active

    1 trial

  24. R788

    RIGEL PHARMACEUTICALS INC

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  25. R932333

    RIGEL PHARMACEUTICALS INC

    Lupus Erythematosus, Discoid

    phase 2 small molecule completed

    1 trial

  26. REGN475

    Regeneron UK Limited

    Osteoarthritis of the Knee

    phase 2 small molecule completed

    1 trial

  27. REGN475

    Regeneron UK Limited

    Osteoarthritis

    phase 2 mab terminated

    1 trial

  28. REGN5069

    Regeneron UK Limited

    Osteoarthritis of the Knee

    phase 2 small molecule terminated

    1 trial

  29. RF-2021-12375251

    Fondazione Telethon ETS

    Refractory Systemic Autoimmune Diseases

    phase 2 small molecule active

    1 trial

  30. RO7790121 placebo, RO7790121

    Hoffmann-La Roche

    Moderate to Severe Rheumatoid Arthritis (RA)

    phase 2 small molecule active

    1 trial

  31. Recombinant Anti-IL-17A Humanized Monoclonal Antibody Injection

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Psoriasis

    phase 2 small molecule active

    1 trial

  32. Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 100 mg

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Gout Arthritis

    phase 2 small molecule active

    1 trial

  33. Rilzabrutinib

    Sanofi-aventis Healthcare Pty Ltd

    Warm autoimmune hemolytic anemia

    phase 2 small molecule active

    1 trial

  34. Roflumilast

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial

  35. Roflumilast Cream 0.3%

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial

  36. Roflumilast foam 0.3%

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial

  37. SAR441566

    Sanofi Pasteur

    Crohn's Disease

    phase 2 small molecule active

    1 trial

  38. SAR442970, NANOBODY® Placebo

    Sanofi-aventis Healthcare Pty Ltd

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  39. SAR443122

    Sanofi Pasteur

    Colitis Ulcerative

    phase 2 small molecule active

    1 trial

  40. SCD-044-19-14

    Lacuna Pharma Pty Ltd

    moderate to severe plaque psoriasis

    phase 2 small molecule active

    1 trial

  41. SPD476-202

    Takeda

    Colitis, Ulcerative

    phase 2 small molecule completed

    1 trial

  42. SPI-62-CL-2003

    Lacuna Pharma Pty Ltd

    Polymyalgia rheumatica (PMR)

    phase 2 small molecule active

    1 trial

  43. SPY001

    Spyre Therapeutics

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  44. SPY002-072

    Spyre Therapeutics

    Rheumatoid Arthritis

    phase 2 small molecule active

    1 trial

  45. SPY123-201

    Spyre Therapeutics

    Moderately to Severely Active Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  46. SPYPBO-101 Placebo to SPY072, SPY072

    Spyre Therapeutics

    Moderately to Severely Active Rheumatologic Disease

    phase 2 small molecule active

    1 trial

  47. Sargramostim

    Hospital Authority, Hong Kong

    Pulmonary Alveolar Proteinosis, Autoimmune

    phase 2 small molecule completed

    1 trial

  48. Sarilumab

    Regeneron UK Limited

    Juvenile Idiopathic Arthritis

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many autoimmune & immunology pipeline programs are tracked?

985 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.